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1JYO
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BU of 1jyo by Molmil
Structure of the Salmonella Virulence Effector SptP in Complex with its Secretion Chaperone SicP
Descriptor: SicP, protein tyrosine phosphatase SptP
Authors:Stebbins, C.E, Galan, J.E.
Deposit date:2001-09-12
Release date:2001-11-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Maintenance of an unfolded polypeptide by a cognate chaperone in bacterial type III secretion.
Nature, 414, 2001
1VCB
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BU of 1vcb by Molmil
THE VHL-ELONGINC-ELONGINB STRUCTURE
Descriptor: PROTEIN (ELONGIN B), PROTEIN (ELONGIN C), PROTEIN (VHL)
Authors:Stebbins, C.E, Kaelin, W.G, Pavletich, N.P.
Deposit date:1999-03-13
Release date:1999-04-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function.
Science, 284, 1999
1YET
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BU of 1yet by Molmil
GELDANAMYCIN BOUND TO THE HSP90 GELDANAMYCIN-BINDING DOMAIN
Descriptor: GELDANAMYCIN, HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YER
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BU of 1yer by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION
Descriptor: HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YES
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BU of 1yes by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "OPEN" CONFORMATION
Descriptor: HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1G4U
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BU of 1g4u by Molmil
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Stebbins, C.E, Galan, J.E.
Deposit date:2000-10-28
Release date:2001-01-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Mol.Cell, 6, 2000
1G4W
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BU of 1g4w by Molmil
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP
Descriptor: PROTEIN TYROSINE PHOSPHATASE SPTP
Authors:Stebbins, C.E, Galan, J.E.
Deposit date:2000-10-28
Release date:2001-01-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Mol.Cell, 6, 2000
6ELC
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BU of 6elc by Molmil
Crystal Structure of O-linked Glycosylated VSG3
Descriptor: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Stebbins, C.E.
Deposit date:2017-09-28
Release date:2018-07-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat.
Nat Microbiol, 3, 2018
7AQX
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BU of 7aqx by Molmil
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB9)
Descriptor: CITRIC ACID, Nanobody VSG2(NB9), SODIUM ION, ...
Authors:Stebbins, C.E, Hempelmann, A.
Deposit date:2020-10-23
Release date:2021-11-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.
Cell Rep, 37, 2021
7AQY
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BU of 7aqy by Molmil
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB11)
Descriptor: Nanobody VSG2(NB11), Variant surface glycoprotein MITAT 1.2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Stebbins, C.E, Hempelmann, A, VanStraaten, M.
Deposit date:2020-10-23
Release date:2021-11-03
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.
Cell Rep, 37, 2021
7AR0
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BU of 7ar0 by Molmil
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB19)
Descriptor: Nanobody VSG2(NB19), Variant surface glycoprotein MITAT 1.2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Stebbins, C.E, Hempelmann, A.
Deposit date:2020-10-23
Release date:2021-11-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.139 Å)
Cite:Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.
Cell Rep, 37, 2021
7AQZ
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BU of 7aqz by Molmil
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB14)
Descriptor: CITRIC ACID, Nanobody VSG2(NB14), SODIUM ION, ...
Authors:Stebbins, C.E, Hempelmann, A, VanStraaten, M.
Deposit date:2020-10-23
Release date:2021-11-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.
Cell Rep, 37, 2021
3EFY
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BU of 3efy by Molmil
Structure of the Cyclomodulin Cif from Pathogenic Escherichia coli
Descriptor: Cif (Cell cycle inhibiting factor)
Authors:Stebbins, C.E, Hsu, Y.
Deposit date:2008-09-10
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the cyclomodulin Cif from pathogenic Escherichia coli.
J.Mol.Biol., 384, 2008
1GRJ
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BU of 1grj by Molmil
GREA TRANSCRIPT CLEAVAGE FACTOR FROM ESCHERICHIA COLI
Descriptor: GREA PROTEIN
Authors:Darst, S.A, Stebbins, C.E.
Deposit date:1995-05-02
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the GreA transcript cleavage factor from Escherichia coli.
Nature, 373, 1995
4G29
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BU of 4g29 by Molmil
Structure of the Catalytic Domain of the Salmonella Virulence Factor SseI
Descriptor: Secreted effector protein sseI
Authors:Stebbins, C.E, Bhaskaran, S.S.
Deposit date:2012-07-11
Release date:2012-11-28
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the catalytic domain of the Salmonella virulence factor SseI.
Acta Crystallogr.,Sect.D, 68, 2012
4GF3
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BU of 4gf3 by Molmil
Structure of a SycH-YopH Chaperone-Effector Complex
Descriptor: Putative yopH targeting protein, Tyrosine-protein phosphatase yopH
Authors:Stebbins, C.E, Vujanac, M.
Deposit date:2012-08-02
Release date:2013-03-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Context-dependent protein folding of a virulence peptide in the bacterial and host environments: structure of an SycH-YopH chaperone-effector complex.
Acta Crystallogr.,Sect.D, 69, 2013
3IEC
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BU of 3iec by Molmil
Helicobacter pylori CagA Inhibits PAR1/MARK Family Kinases by Mimicking Host Substrates
Descriptor: Cytotoxicity-associated immunodominant antigen, Serine/threonine-protein kinase MARK2
Authors:Stebbins, C.E, Nesic, D, Miller, M.
Deposit date:2009-07-22
Release date:2009-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates.
Nat.Struct.Mol.Biol., 17, 2010
3LW9
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BU of 3lw9 by Molmil
Structure of a Cytoplasmic Domain of Salmonella InvA
Descriptor: Invasion protein invA
Authors:Stebbins, C.E, Lilic, M, Quezada, C.M.
Deposit date:2010-02-23
Release date:2010-05-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved domain in type III secretion links the cytoplasmic domain of InvA to elements of the basal body.
Acta Crystallogr.,Sect.D, 66, 2010
1Q5Z
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BU of 1q5z by Molmil
Crystal Structure of the C-terminal Actin Binding Domain of Salmonella Invasion Protein A (SipA)
Descriptor: SipA
Authors:Stebbins, C.E, Lilic, M, Galkin, V.E, Orlova, A, VanLoock, M.S, Egelman, E.H.
Deposit date:2003-08-11
Release date:2003-10-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms.
Science, 301, 2003
6Z8H
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BU of 6z8h by Molmil
Crystal structure of Variant Surface Glycoprotein VSG13
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variant surface glycoprotein MITat 1.13, ...
Authors:Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J.
Deposit date:2020-06-02
Release date:2021-03-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z8G
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BU of 6z8g by Molmil
Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure.
Descriptor: BROMIDE ION, SULFATE ION, Variant surface glycoprotein MITat 1.13, ...
Authors:Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J.
Deposit date:2020-06-02
Release date:2021-03-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
4IRV
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BU of 4irv by Molmil
Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
Descriptor: Apoptosis-stimulating of p53 protein 2, Cytotoxicity-associated immunodominant antigen
Authors:Stebbins, C.E, Nesic, D.
Deposit date:2013-01-15
Release date:2014-01-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
Proc.Natl.Acad.Sci.USA, 111, 2014
4G6T
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BU of 4g6t by Molmil
Structure of the HopA1-SchA Chaperone-Effector Complex
Descriptor: Type III chaperone protein ShcA, Type III effector HopA1
Authors:Stebbins, C.E, Janjusevic, R, Quezada, C.M.
Deposit date:2012-07-19
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structure of the HopA1(21-102)-ShcA chaperone-effector complex of Pseudomonas syringae reveals conservation of a virulence factor binding motif from animal to plant pathogens.
J.Bacteriol., 195, 2013
4G2B
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BU of 4g2b by Molmil
Structure of the Catalytic Domain of the Salmonella Virulence Factor SseI
Descriptor: Secreted effector protein sseI
Authors:Stebbins, C.E, Bhaskaran, S.S.
Deposit date:2012-07-11
Release date:2012-11-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the catalytic domain of the Salmonella virulence factor SseI.
Acta Crystallogr.,Sect.D, 68, 2012
2GWK
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BU of 2gwk by Molmil
SpvB ADP-ribosylated actin: orthorhombic crystal form
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006

 

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