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1EHY
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BU of 1ehy by Molmil
X-ray structure of the epoxide hydrolase from agrobacterium radiobacter ad1
Descriptor: POTASSIUM ION, PROTEIN (SOLUBLE EPOXIDE HYDROLASE)
Authors:Nardini, M, Ridder, I.S, Rozeboom, H.J, Kalk, K.H, Rink, R, Janssen, D.B, Dijkstra, B.W.
Deposit date:1998-10-17
Release date:1999-10-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides.
J.Biol.Chem., 274, 1999
1HDE
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BU of 1hde by Molmil
HALOALKANE DEHALOGENASE MUTANT WITH PHE 172 REPLACED WITH TRP
Descriptor: HALOALKANE DEHALOGENASE
Authors:Ridder, I.S, Kalk, K.H, Dijkstra, B.W.
Deposit date:1996-08-08
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range.
Biochemistry, 35, 1996
2H1Z
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BU of 2h1z by Molmil
Structure of a dual-target spider toxin
Descriptor: Hybrid atracotoxin
Authors:Sollod, B.L, Maciejewski, M.W, KIng, G.F.
Deposit date:2006-05-17
Release date:2007-05-22
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:A dual-target, self-synergizing toxin from spider venom
To be Published
7MSQ
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BU of 7msq by Molmil
Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)
Descriptor: AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, CHLORIDE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2021-05-12
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Immunity, 54, 2021
7KZB
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BU of 7kzb by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Fab heavy chain of CR3014-C8 antibody, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2020-12-10
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
7KZC
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BU of 7kzc by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Descriptor: CHLORIDE ION, Fab heavy chain of m396-B10 antibody, Fab light chain of m396-B10 antibody
Authors:Langley, D.B, Christ, D.
Deposit date:2020-12-10
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
7KZA
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BU of 7kza by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Descriptor: CHLORIDE ION, Fab fragment heavy chain of anti-CoV2-RBD antibody variant CR3022-B6, Fab fragment light chain of anti-CoV2-RBD antibody variant CR3022-B6, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2020-12-10
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
6H9O
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BU of 6h9o by Molmil
Complex of the periplasmic domains of bacterial cell division proteins FtsQ and FtsB
Descriptor: Cell division protein FtsB, Cell division protein FtsQ
Authors:Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2018-08-05
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB.
MBio, 9, 2018
6H9N
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BU of 6h9n by Molmil
Complex of the periplasmic domains of bacterial cell division proteins FtsQ and FtsB
Descriptor: Cell division protein FtsB, Cell division protein FtsQ
Authors:Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2018-08-05
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB.
MBio, 9, 2018
7PZC
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BU of 7pzc by Molmil
Cryo-EM structure of the NLRP3 decamer bound to the inhibitor CRID3
Descriptor: 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ...
Authors:Hochheiser, I.V, Pilsl, M, Hagelueken, G, Engel, C, Geyer, M.
Deposit date:2021-10-12
Release date:2022-01-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.
Nature, 604, 2022
6P4B
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BU of 6p4b by Molmil
HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S)
Descriptor: CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P4C
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BU of 6p4c by Molmil
HyHEL10 Fab carrying four heavy chain mutations (HyHEL10-4x): L4F, Y33H, S56N, and Y58F
Descriptor: CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P4D
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BU of 6p4d by Molmil
Hen egg lysozyme (HEL) containing three point mutations (HEL3x): R21Q, R73E, and D101R
Descriptor: CHLORIDE ION, GLYCEROL, Lysozyme C, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P4A
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BU of 6p4a by Molmil
HyHEL10 Fab complexed with hen egg lysozyme carrying two mutations (HEL2x-rigid): R21Q and R73E
Descriptor: HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, Lysozyme C
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
5V8G
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BU of 5v8g by Molmil
Pekin duck lysozyme isoform I (DEL-I)
Descriptor: CHLORIDE ION, THIOCYANATE ION, lysozyme isoform I
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5V3B
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BU of 5v3b by Molmil
Human A20 OTU domain (WT) with acetamidylated C103
Descriptor: Tumor necrosis factor alpha-induced protein 3
Authors:Langley, D.B, Christ, D, Grey, S.
Deposit date:2017-03-07
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nat.Immunol., 20, 2019
5V92
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BU of 5v92 by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, lysozyme isoform III
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5V94
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BU of 5v94 by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), cubic form
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5V3P
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BU of 5v3p by Molmil
Human A20 OTU domain (I325N) with acetamidylated C103
Descriptor: Tumor necrosis factor alpha-induced protein 3
Authors:Langley, D.B, Christ, D, Grey, S.
Deposit date:2017-03-07
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nat.Immunol., 20, 2019
5VAS
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BU of 5vas by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
Descriptor: GLYCEROL, Lysozyme, PHOSPHATE ION
Authors:Christie, M, Christ, D, Langley, D.B.
Deposit date:2017-03-27
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5VJO
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BU of 5vjo by Molmil
Complex between HyHEL10 Fab fragment heavy chain mutant I29F and Pekin duck egg lysozyme isoform I (DEL-I)
Descriptor: CHLORIDE ION, HyHEL10 heavy chain Fab fragment carrying I29F mutation., HyHEL10 light chain Fab fragment, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2017-04-19
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018
5VJQ
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BU of 5vjq by Molmil
Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I)
Descriptor: CHLORIDE ION, GLYCEROL, HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2017-04-19
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018

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数据于2024-07-17公开中

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