149D
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136D
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135D
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1KDX
| KIX DOMAIN OF MOUSE CBP (CREB BINDING PROTEIN) IN COMPLEX WITH PHOSPHORYLATED KINASE INDUCIBLE DOMAIN (PKID) OF RAT CREB (CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN), NMR 17 STRUCTURES | Descriptor: | CBP, CREB | Authors: | Radhakrishnan, I, Perez-Alvarado, G.C, Dyson, H.J, Wright, P.E. | Deposit date: | 1997-09-16 | Release date: | 1998-11-25 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell(Cambridge,Mass.), 91, 1997
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177D
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134D
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1S5Q
| Solution Structure of Mad1 SID-mSin3A PAH2 Complex | Descriptor: | MAD protein, Sin3a protein | Authors: | Swanson, K.A, Knoepfler, P.S, Huang, K, Kang, R.S, Cowley, S.M, Laherty, C.D, Eisenman, R.N, Radhakrishnan, I. | Deposit date: | 2004-01-21 | Release date: | 2004-07-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. Nat.Struct.Mol.Biol., 11, 2004
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7SXI
| Solution Structure of Sds3 Capped Tudor Domain | Descriptor: | Sin3 histone deacetylase corepressor complex component SDS3 | Authors: | Marcum, R.D, Radhakrishnan, I. | Deposit date: | 2021-11-23 | Release date: | 2022-01-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes. J.Biol.Chem., 298, 2022
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1S5R
| Solution Structure of HBP1 SID-mSin3A PAH2 Complex | Descriptor: | Sin3a protein, high mobility group box transcription factor 1 | Authors: | Swanson, K.A, Knoepfler, P.S, Huang, K, Kang, R.S, Cowley, S.M, Laherty, C.D, Eisenman, R.N, Radhakrishnan, I. | Deposit date: | 2004-01-21 | Release date: | 2004-07-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. Nat.Struct.Mol.Biol., 11, 2004
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2RMS
| Solution structure of the mSin3A PAH1-SAP25 SID complex | Descriptor: | MSin3A-binding protein, Paired amphipathic helix protein Sin3a | Authors: | Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. | Deposit date: | 2007-11-14 | Release date: | 2008-01-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor J.Mol.Biol., 375, 2007
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2RMR
| Solution structure of mSin3A PAH1 domain | Descriptor: | Paired amphipathic helix protein Sin3a | Authors: | Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. | Deposit date: | 2007-11-14 | Release date: | 2008-01-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor J.Mol.Biol., 375, 2007
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1SLO
| FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3') | Authors: | Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D. | Deposit date: | 1996-05-24 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the donor site of a trans-splicing RNA. Structure, 4, 1996
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1SLP
| FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, 16 STRUCTURES | Descriptor: | RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3') | Authors: | Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D. | Deposit date: | 1996-05-24 | Release date: | 1997-04-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the donor site of a trans-splicing RNA. Structure, 4, 1996
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8GA8
| Structure of the yeast (HDAC) Rpd3L complex | Descriptor: | Histone deacetylase RPD3, Transcriptional regulatory protein DEP1, Transcriptional regulatory protein PHO23, ... | Authors: | Patel, A.B, Radhakrishnan, I, He, Y. | Deposit date: | 2023-02-22 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. Nat Commun, 14, 2023
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2FF0
| Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter | Descriptor: | CTGTGGCCCTGAGCC, GGCTCAGGGCCACAG, Steroidogenic factor 1, ... | Authors: | Little, T.H, Zhang, Y, Matulis, C.K, Weck, J, Zhang, Z, Ramachandran, A, Mayo, K.E, Radhakrishnan, I. | Deposit date: | 2005-12-17 | Release date: | 2006-04-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability. Mol.Endocrinol., 20, 2006
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2G3Q
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4HTM
| Mechanism of CREB Recognition and Coactivation by the CREB Regulated Transcriptional Coactivator CRTC2 | Descriptor: | CREB-regulated transcription coactivator 2, ZINC ION | Authors: | Luo, Q, Viste, K, Urday-Zaa, J.C, Kumar, G.S, Tsai, W.-W, Talai, A, Mayo, K, Montminy, M, Radhakrishnan, I. | Deposit date: | 2012-11-01 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation Proc.Natl.Acad.Sci.USA, 2012
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2N2H
| Solution structure of Sds3 in complex with Sin3A | Descriptor: | Paired amphipathic helix protein Sin3a, Sin3 histone deacetylase corepressor complex component SDS3 | Authors: | Clark, M, Radhakrishnan, I. | Deposit date: | 2015-05-08 | Release date: | 2015-07-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex. Proc.Natl.Acad.Sci.USA, 112, 2015
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2N1D
| Solution structure of the MRG15-MRGBP complex | Descriptor: | MRG/MORF4L-binding protein, Mortality factor 4-like protein 1 | Authors: | Xie, T, Zmysloski, A.M, Zhang, Y, Radhakrishnan, I. | Deposit date: | 2015-03-27 | Release date: | 2015-05-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Multi-specificity of MRG Domains. Structure, 23, 2015
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4ZQA
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2L3M
| Solution structure of the putative copper-ion-binding protein from Bacillus anthracis str. Ames | Descriptor: | Copper-ion-binding protein | Authors: | Zhang, Y, Winsor, J, Dubrovska, I, Anderson, W, Radhakrishnan, I, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-09-16 | Release date: | 2011-01-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | To be published To be Published
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1TF3
| TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES | Descriptor: | 5S RNA GENE, TRANSCRIPTION FACTOR IIIA, ZINC ION | Authors: | Foster, M.P, Wuttke, D.S, Radhakrishnan, I, Case, D.A, Gottesfeld, J.M, Wright, P.E. | Deposit date: | 1997-07-01 | Release date: | 1997-09-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Nat.Struct.Biol., 4, 1997
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1OTR
| Solution Structure of a CUE-Ubiquitin Complex | Descriptor: | Ubiquitin, protein Cue2 | Authors: | Kang, R.S, Daniels, C.M, Salerno, W.J, Radhakrishnan, I. | Deposit date: | 2003-03-22 | Release date: | 2003-06-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of a CUE-Ubiquitin Complex Reveals a Conserved Mode
of Ubiquitin Binding Cell(Cambridge,Mass.), 113, 2003
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1Q0V
| Solution Structure of Tandem UIMs of Vps27 | Descriptor: | hydrophilic protein; has cysteine rich putative zinc finger essential for function; Vps27p | Authors: | Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I. | Deposit date: | 2003-07-17 | Release date: | 2003-12-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation. Embo J., 22, 2003
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1Q0W
| Solution structure of Vps27 amino-terminal UIM-ubiquitin complex | Descriptor: | Ubiquitin, Vacuolar protein sorting-associated protein VPS27 | Authors: | Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I. | Deposit date: | 2003-07-17 | Release date: | 2003-10-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of Vps27 UIM-Ubiquitin Complex Important for Endosomal Sorting and Receptor Downregulation Embo J., 22, 2003
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