1SLP

FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, 16 STRUCTURES

Summary for 1SLP

• Entry DOI: 10.2210/pdb1slp/pdb
• Descriptor: RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3') (1 entity in total)
• Functional Keywords: splice donor site, stem-loop, ribonucleic acid, rna
• Biological source: Caenorhabditis elegans
• Total number of polymer chains: 1
• Total formula weight: 6063.64

Authors

Greenbaum, N.L.,Radhakrishnan, I.,Patel, D.J.,Hirsh, D. (deposition date: 1996-05-24, release date: 1997-04-21, Last modification date: 2024-05-22)

Primary citation

Greenbaum, N.L.,Radhakrishnan, I.,Patel, D.J.,Hirsh, D.
Solution structure of the donor site of a trans-splicing RNA.
Structure, 4:725-733, 1996

PubMed Abstract: RNA splicing is both ubiquitous and essential for the maturation of precursor mRNA molecules in eukaryotes. The process of trans-splicing involves the transfer of a short spliced leader (SL) RNA sequence to a consensus acceptor site on a separate pre-mRNA transcript. In Caenorhabditis elegans, a majority of pre-mRNA transcripts receive the 22-nucleotide SL from the SL1 RNA. Very little is known about the various roles that RNA structures play in the complex conformational rearrangements and reactions involved in premRNA splicing.

PubMed: 8805553
DOI: 10.1016/S0969-2126(96)00078-0

Experimental method

SOLUTION NMR