3BUN
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![BU of 3bun by Molmil](/molmil-images/mine/3bun) | Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4 | Descriptor: | 13-meric peptide from Protein sprouty homolog 4, E3 ubiquitin-protein ligase CBL | Authors: | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | Deposit date: | 2008-01-03 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUX
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![BU of 3bux by Molmil](/molmil-images/mine/3bux) | Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met | Descriptor: | 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL | Authors: | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | Deposit date: | 2008-01-03 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUM
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![BU of 3bum by Molmil](/molmil-images/mine/3bum) | Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2 | Descriptor: | E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2 | Authors: | Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J. | Deposit date: | 2008-01-03 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUW
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![BU of 3buw by Molmil](/molmil-images/mine/3buw) | Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk | Descriptor: | 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL | Authors: | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | Deposit date: | 2008-01-03 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUO
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![BU of 3buo by Molmil](/molmil-images/mine/3buo) | Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor' | Descriptor: | 13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL | Authors: | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | Deposit date: | 2008-01-03 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3HJ6
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![BU of 3hj6 by Molmil](/molmil-images/mine/3hj6) | Structure of Halothermothrix orenii fructokinase (FRK) | Descriptor: | Fructokinase | Authors: | Chua, T.K, Seetharaman, J, Kasprzak, J.M, Ng, C, Patel, B.K, Love, C, Bujnicki, J.M, Sivaraman, J. | Deposit date: | 2009-05-21 | Release date: | 2010-06-09 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a fructokinase homolog from Halothermothrix orenii J.Struct.Biol., 171, 2010
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3EM6
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![BU of 3em6 by Molmil](/molmil-images/mine/3em6) | Crystal structure of I50L/A71V mutant of hiv-1 protease in complex with inhibitor darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, PHOSPHATE ION, ... | Authors: | Royer, C.J, King, N.M, Prabu-Jeyabalan, M, Ng, C, Nalivaika, E.A, Schiffer, C.A. | Deposit date: | 2008-09-23 | Release date: | 2009-09-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and structural studies on atazanavir specific I50L drug-resistant HIV-1 protease mutant. To be Published
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7K3Q
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![BU of 7k3q by Molmil](/molmil-images/mine/7k3q) | An ultra-potent human neutralizing antibody locks the SARS-CoV-2 spike in the closed conformation | Descriptor: | 1,2-ETHANEDIOL, Fab fragment of S2E12 monoclonal antibody, heavy chain, ... | Authors: | Snell, G, Czudnochowski, N, Ng, C. | Deposit date: | 2020-09-12 | Release date: | 2020-10-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020
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4K7P
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![BU of 4k7p by Molmil](/molmil-images/mine/4k7p) | |
1A1W
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![BU of 1a1w by Molmil](/molmil-images/mine/1a1w) | FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | Descriptor: | FADD PROTEIN | Authors: | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | Deposit date: | 1997-12-18 | Release date: | 1998-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature, 392, 1998
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1A1Z
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![BU of 1a1z by Molmil](/molmil-images/mine/1a1z) | FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | Descriptor: | FADD PROTEIN | Authors: | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | Deposit date: | 1997-12-18 | Release date: | 1998-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature, 392, 1998
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3VK6
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![BU of 3vk6 by Molmil](/molmil-images/mine/3vk6) | |
6VBH
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![BU of 6vbh by Molmil](/molmil-images/mine/6vbh) | Human XPG endonuclease catalytic domain | Descriptor: | DNA repair protein complementing XP-G cells,Flap endonuclease 1, SULFATE ION | Authors: | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | Deposit date: | 2019-12-18 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc.Natl.Acad.Sci.USA, 117, 2020
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3PLF
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![BU of 3plf by Molmil](/molmil-images/mine/3plf) | Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain | Descriptor: | CALCIUM ION, CHLORIDE ION, E3 ubiquitin-protein ligase CBL, ... | Authors: | Sun, Q, Sivaraman, J. | Deposit date: | 2010-11-15 | Release date: | 2010-12-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding Febs Lett., 585, 2011
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3OB1
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![BU of 3ob1 by Molmil](/molmil-images/mine/3ob1) | |
3OB2
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![BU of 3ob2 by Molmil](/molmil-images/mine/3ob2) | |
7K43
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![BU of 7k43 by Molmil](/molmil-images/mine/7k43) | |
7K45
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![BU of 7k45 by Molmil](/molmil-images/mine/7k45) | |
7K4N
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![BU of 7k4n by Molmil](/molmil-images/mine/7k4n) | |