1D5R
| Crystal Structure of the PTEN Tumor Suppressor | Descriptor: | L(+)-TARTARIC ACID, PHOSPHOINOSITIDE PHOSPHATASE PTEN | Authors: | Lee, J.O, Yang, H, Georgescu, M.-M, Di Cristofano, A, Pavletich, N.P. | Deposit date: | 1999-10-11 | Release date: | 1999-11-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell(Cambridge,Mass.), 99, 1999
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1GUX
| RB POCKET BOUND TO E7 LXCXE MOTIF | Descriptor: | ONCOPROTEIN, RETINOBLASTOMA PROTEIN | Authors: | Lee, J.O, Russo, A.A, Pavletich, N.P. | Deposit date: | 1997-11-15 | Release date: | 1998-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature, 391, 1998
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2Z82
| Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | Descriptor: | (2R)-3-{[(2R)-2-AMINO-3-HYDROXYPROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | Deposit date: | 2007-08-30 | Release date: | 2007-10-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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2Z7X
| Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | Authors: | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | Deposit date: | 2007-08-29 | Release date: | 2007-10-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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2Z81
| Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | Descriptor: | (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, ... | Authors: | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | Deposit date: | 2007-08-30 | Release date: | 2007-10-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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2Z80
| Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, Variable lymphocyte receptor B | Authors: | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | Deposit date: | 2007-08-30 | Release date: | 2007-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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6K65
| Application of anti-helix antibodies in protein structure determination (9014-1P4B) | Descriptor: | 1P4B variable heavy chain, 1P4B variable light chain, Immunoglobulin G-binding protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K6B
| Application of anti-helix antibodies in protein structure determination (8496-3LRH) | Descriptor: | 3LRH intrabody, Protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-02 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K3M
| Application of anti-helix antibodies in protein structure determination (8189-3LRH) | Descriptor: | 3LRH intrabody, SpA IgG-binding domain protein,Protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-05-20 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K67
| Application of anti-helix antibodies in protein structure determination (9011-3LRH) | Descriptor: | 3LRH introbody, CALCIUM ION, Engineered calmodulin | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K64
| Application of anti-helix antibodies in protein structure determination (8188-3LRH) | Descriptor: | 3LRH intrabody, Protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.933 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K6A
| Application of anti-helix antibodies in protein structure determination (8188cys-3LRHcys) | Descriptor: | 3LRH intrabody, Engineered Protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-02 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K69
| Application of anti-helix antibodies in protein structure determination (9213-3LRH) | Descriptor: | 3LRH intrabody, Engineered T4 lysozyme | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6K68
| Application of anti-helix antibodies in protein structure determination (8420-3MNZ) | Descriptor: | 3MNZ Variable heavy chain, 3MNZ Variable light chain, Protein A | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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3Q8W
| A b-aminoacyl containing thiazolidine derivative and DPPIV complex | Descriptor: | Dipeptidyl peptidase 4, N-(4-{[({(2R)-3-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,3-thiazolidin-2-yl}carbonyl)amino]methyl}phenyl)-D-valine | Authors: | Lee, J.O, Song, D.H. | Deposit date: | 2011-01-07 | Release date: | 2011-03-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | Discovery of b-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors To be Published
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2O6S
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2O6Q
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2O6R
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5CBO
| Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus | Descriptor: | mbp3-16,Immunoglobulin G-binding protein A | Authors: | Jeong, W.H, Lee, H, Song, D.H, Lee, J.O. | Deposit date: | 2015-07-01 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker. Nat Commun, 7, 2016
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5COC
| Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus | Descriptor: | CALCIUM ION, Immunoglobulin G-binding protein A,Calmodulin | Authors: | Jeong, W.H, Lee, H, Song, D.H, Lee, J.O. | Deposit date: | 2015-07-20 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6691 Å) | Cite: | Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker. Nat Commun, 7, 2016
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4M4D
| Crystal structure of lipopolysaccharide binding protein | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipopolysaccharide-binding protein | Authors: | Eckert, J.K, Kim, Y.J, Kim, J.I, Gurtler, K, Oh, D.Y, Ploeg, A.H, Pickkers, P, Lundvall, L, Hamann, L, Giamarellos-Bourboulis, E, Kubarenko, A.V, Weber, A.N, Kabesch, M, Kumpf, O, An, H.J, Lee, J.O, Schumann, R.R. | Deposit date: | 2013-08-07 | Release date: | 2013-10-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.909 Å) | Cite: | The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity. Immunity, 39, 2013
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8J26
| CryoEM structure of SARS CoV-2 RBD and Aptamer complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-4, AM047-6, ... | Authors: | Rahman, M.S, Jang, S.K, Lee, J.O. | Deposit date: | 2023-04-14 | Release date: | 2023-06-21 | Last modified: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection. Molecules, 28, 2023
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8J1Q
| CryoEM structure of SARS CoV-2 RBD and Aptamer complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-0, AM047-0, ... | Authors: | Rahman, M.S, Jang, S.K, Lee, J.O. | Deposit date: | 2023-04-13 | Release date: | 2023-06-21 | Last modified: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection. Molecules, 28, 2023
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1BI7
| MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
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1BI8
| MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
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