4WO2
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4WO3
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![BU of 4wo3 by Molmil](/molmil-images/mine/4wo3) | THE SECOND C-KIT DNA QUADRUPLEX CRYSTAL STRUCTURE | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION | Authors: | Wei, D, Neidle, S. | Deposit date: | 2014-10-15 | Release date: | 2014-10-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | THE SECOND C-KIT1 DNA QUADRUPLEX CRYSTAL STRUCTURE TO BE PUBLISHED
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4H29
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![BU of 4h29 by Molmil](/molmil-images/mine/4h29) | B-raf dimer DNA quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*GP*GP*AP*GP*GP*GP*GP*GP*AP*AP*GP*GP*GP*A)-3'), POTASSIUM ION | Authors: | Wei, D, Parkinson, G, Neidle, S. | Deposit date: | 2012-09-12 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex. J.Am.Chem.Soc., 135, 2013
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2JTU
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![BU of 2jtu by Molmil](/molmil-images/mine/2jtu) | NMR structure of iota-RXIA(38) | Descriptor: | I-superfamily conotoxin r11a | Authors: | Wei, D, Norton, R. | Deposit date: | 2007-08-06 | Release date: | 2008-08-19 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | NMR structure of iota-RXIA(38) To be Published
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3QXR
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4QKX
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![BU of 4qkx by Molmil](/molmil-images/mine/4qkx) | Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody | Descriptor: | 4-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(2-sulfanylethoxy)phenyl]ethyl}amino)ethyl]benzene-1,2-diol, Beta-2 adrenergic receptor, R9 protein, ... | Authors: | Weichert, D, Kruse, A.C, Manglik, A, Hiller, C, Zhang, C, Huebner, H, Kobilka, B.K, Gmeiner, P. | Deposit date: | 2014-06-10 | Release date: | 2014-07-23 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Covalent agonists for studying G protein-coupled receptor activation. Proc.Natl.Acad.Sci.USA, 111, 2014
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1A6X
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![BU of 1a6x by Molmil](/molmil-images/mine/1a6x) | STRUCTURE OF THE APO-BIOTIN CARBOXYL CARRIER PROTEIN (APO-BCCP87) OF ESCHERICHIA COLI ACETYL-COA CARBOXYLASE, NMR, 49 STRUCTURES | Descriptor: | APO-BIOTIN CARBOXYL CARRIER PROTEIN OF ACETYL-COA CARBOXYLASE | Authors: | Yao, X, Wei, D, Soden Junior, C, Summers, M.F, Beckett, D. | Deposit date: | 1998-03-04 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the carboxy-terminal fragment of the apo-biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase. Biochemistry, 36, 1997
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1WM7
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![BU of 1wm7 by Molmil](/molmil-images/mine/1wm7) | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch, 9 structures | Descriptor: | Neurotoxin BmP01 | Authors: | Wu, G, Li, Y, Wei, D, He, F, Jiang, S, Hu, G, Wu, H, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 276, 2000
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3VZ1
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3VZ2
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3VZ3
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![BU of 3vz3 by Molmil](/molmil-images/mine/3vz3) | Structural insights into substrate and cofactor selection by sp2771 | Descriptor: | 4-oxobutanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase | Authors: | Yuan, Y.A, Yuan, Z, Yin, B, Wei, D. | Deposit date: | 2012-10-09 | Release date: | 2013-07-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase J.Struct.Biol., 182, 2013
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3VZ0
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![BU of 3vz0 by Molmil](/molmil-images/mine/3vz0) | Structural insights into cofactor and substrate selection by Gox0499 | Descriptor: | NONAETHYLENE GLYCOL, Putative NAD-dependent aldehyde dehydrogenase | Authors: | Yuan, Y.A, Yuan, Z, Yin, B, Wei, D. | Deposit date: | 2012-10-09 | Release date: | 2013-07-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase J.Struct.Biol., 182, 2013
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7YPN
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![BU of 7ypn by Molmil](/molmil-images/mine/7ypn) | Crystal structure of transaminase CC1012 mutant M9 complexed with PLP | Descriptor: | 1,2-ETHANEDIOL, Aspartate aminotransferase family protein, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yang, L, Wang, H, Wei, D. | Deposit date: | 2022-08-03 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.049 Å) | Cite: | Mechanism-Guided Computational Design of omega-Transaminase by Reprograming of High-Energy-Barrier Steps. Angew.Chem.Int.Ed.Engl., 61, 2022
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7YPM
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![BU of 7ypm by Molmil](/molmil-images/mine/7ypm) | Crystal structure of transaminase CC1012 complexed with PLP and L-alanine | Descriptor: | 1,2-ETHANEDIOL, ALANINE, Aspartate aminotransferase family protein, ... | Authors: | Yang, L, Wang, H, Wei, D. | Deposit date: | 2022-08-03 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.984 Å) | Cite: | Mechanism-Guided Computational Design of omega-Transaminase by Reprograming of High-Energy-Barrier Steps. Angew.Chem.Int.Ed.Engl., 61, 2022
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4EHR
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![BU of 4ehr by Molmil](/molmil-images/mine/4ehr) | Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide | Descriptor: | 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide, Bcl-2-like protein 1, IMIDAZOLE | Authors: | Schroeder, G.M, Wei, D, Banfi, P, Cai, Z, Lippy, J, Menichincheri, M, Modugno, M, Naglich, J, Penhallow, B, Perez, H.L, Sack, J, Schmidt, R.J, Tebben, A, Yan, C, Zhang, L, Galvani, A, Lombardo, L.J, Borzilleri, R.M. | Deposit date: | 2012-04-03 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorg.Med.Chem.Lett., 22, 2012
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2JRY
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![BU of 2jry by Molmil](/molmil-images/mine/2jry) | Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin | Descriptor: | I-superfamily conotoxin r11a | Authors: | Buczek, O, Wei, D, Babon, J, Yang, X, Fiedler, B, Chen, P, Yoshikami, D, Olivera, B, Bulaj, G, Norton, R. | Deposit date: | 2007-06-29 | Release date: | 2007-10-23 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure and sodium channel activity of an excitatory I1-superfamily conotoxin. Biochemistry, 46, 2007
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6Z6F
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![BU of 6z6f by Molmil](/molmil-images/mine/6z6f) | HDAC-PC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6Z6O
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![BU of 6z6o by Molmil](/molmil-images/mine/6z6o) | HDAC-TC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6Z6H
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![BU of 6z6h by Molmil](/molmil-images/mine/6z6h) | HDAC-DC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (8.55 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6Z6P
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![BU of 6z6p by Molmil](/molmil-images/mine/6z6p) | HDAC-PC-Nuc | Descriptor: | DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (4.43 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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5D70
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![BU of 5d70 by Molmil](/molmil-images/mine/5d70) | Crystal structure of MOR03929, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF | Descriptor: | Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, heavy chain, ... | Authors: | Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. | Deposit date: | 2015-08-13 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
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5D7S
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![BU of 5d7s by Molmil](/molmil-images/mine/5d7s) | Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment | Descriptor: | (2S,3S)-butane-2,3-diol, Immunglobulin G1 Fab fragment, heavy chain, ... | Authors: | Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. | Deposit date: | 2015-08-14 | Release date: | 2015-10-14 | Last modified: | 2016-01-13 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
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5D72
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![BU of 5d72 by Molmil](/molmil-images/mine/5d72) | Crystal structure of MOR04252, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF | Descriptor: | DI(HYDROXYETHYL)ETHER, Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, ... | Authors: | Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. | Deposit date: | 2015-08-13 | Release date: | 2015-10-14 | Last modified: | 2016-01-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
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3HKF
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![BU of 3hkf by Molmil](/molmil-images/mine/3hkf) | Murine unglycosylated IgG Fc fragment | Descriptor: | CHLORIDE ION, Igh protein, MAGNESIUM ION | Authors: | Feige, M.J, Nath, S, Catharino, S.R, Weinfurtner, D, Steinbacher, S, Buchner, J. | Deposit date: | 2009-05-23 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the murine unglycosylated IgG1 Fc fragment J.Mol.Biol., 391, 2009
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1CGL
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![BU of 1cgl by Molmil](/molmil-images/mine/1cgl) | Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor | Descriptor: | CALCIUM ION, FIBROBLAST COLLAGENASE, N-[(1S)-3-{[(benzyloxy)carbonyl]amino}-1-carboxypropyl]-L-leucyl-N-(2-morpholin-4-ylethyl)-L-phenylalaninamide, ... | Authors: | Lovejoy, B, Cleasby, A, Hassell, A.M, Longley, K, Luther, M.A, Weigl, D, Mcgeehan, G, Mcelroy, A.B, Drewry, D, Lambert, M.H, Jordan, S.R. | Deposit date: | 1993-11-17 | Release date: | 1995-02-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor. Science, 263, 1994
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