8WO8
| Crystal Structure of an RNA-binding protein, FAU-1, from Pyrococcus furiosus | Descriptor: | Probable ribonuclease FAU-1, RNA (5'-R(P*AP*UP*A)-3') | Authors: | Kawai, G, Okada, K, Baba, S, Sato, A, Sakamoto, T, Kanai, A. | Deposit date: | 2023-10-06 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus. J.Biochem., 175, 2024
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2IP4
| Crystal Structure of Glycinamide Ribonucleotide Synthetase from Thermus thermophilus HB8 | Descriptor: | Phosphoribosylamine--glycine ligase, SULFATE ION | Authors: | Sampei, G, Baba, S, Kanagawa, M, Yanai, H, Ishii, T, Kawai, H, Fukai, Y, Ebihara, A, Nakagawa, N, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-10-11 | Release date: | 2007-10-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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2RVO
| Solution structure of a reverse transcriptase recognition site of a LINE RNA from zebrafish | Descriptor: | RNA (34-MER) | Authors: | Otsu, M, Norose, N, Arai, N, Terao, R, Kajikawa, M, Okada, N, Kawai, G. | Deposit date: | 2016-02-03 | Release date: | 2017-02-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a reverse transcriptase recognition site of a LINE RNA from zebrafish. J. Biochem., 162, 2017
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2RRC
| Solution Structure of RNA aptamer against AML1 Runt domain | Descriptor: | 5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3' | Authors: | Nomura, Y, Fujiwara, K, Chiba, M, Fukunaga, J, Tanaka, Y, Iibuchi, H, Tanaka, T, Nakamura, Y, Kawai, G, Kozu, T, Sakamoto, T. | Deposit date: | 2010-06-23 | Release date: | 2011-06-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding To be Published
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1J1H
| Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus | Descriptor: | Small Protein B | Authors: | Someya, T, Nameki, N, Hosoi, H, Suzuki, S, Hatanaka, H, Fujii, M, Terada, T, Shirouzu, M, Inoue, Y, Shibata, T, Kuramitsu, S, Yokoyama, S, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-12-04 | Release date: | 2003-02-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus FEBS Lett., 535, 2003
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3HSB
| Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer | Descriptor: | Protein hfq, RNA (5'-R(*AP*GP*AP*GP*AP*GP*A)-3') | Authors: | Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K. | Deposit date: | 2009-06-10 | Release date: | 2010-06-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq Nucleic Acids Res., 40, 2012
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6JRQ
| Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus | Descriptor: | 1,2-ETHANEDIOL, Adenylosuccinate synthetase, INOSINIC ACID | Authors: | Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2019-04-05 | Release date: | 2020-04-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus HB8 To Be Published
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3W7B
| Crystal structure of formyltetrahydrofolate deformylase from Thermus thermophilus HB8 | Descriptor: | Formyltetrahydrofolate deformylase | Authors: | Sampei, G, Yanagida, Y, Ogata, N, Kusano, M, Terao, K, Kawai, H, Fukai, Y, Kanagawa, M, Inoue, Y, Baba, S, Kawai, G. | Deposit date: | 2013-02-28 | Release date: | 2014-01-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structures and reaction mechanisms of the two related enzymes, PurN and PurU J.Biochem., 154, 2013
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6J61
| Crystal Structure of Thymidylate Synthase, Thy1, from Thermus thermophilus having an Extra C Terminal Domain | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, PHOSPHATE ION | Authors: | Ogawa, A, Sampei, G, Kawai, G. | Deposit date: | 2019-01-12 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the flavin-dependent thymidylate synthase Thy1 from Thermus thermophilus with an extra C-terminal domain. Acta Crystallogr.,Sect.F, 75, 2019
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1K2G
| Structural basis for the 3'-terminal guanosine recognition by the group I intron | Descriptor: | 5'-R(*CP*AP*GP*AP*CP*UP*UP*CP*GP*GP*UP*CP*GP*CP*AP*GP*AP*GP*AP*UP*GP*G)-3' | Authors: | Kitamura, Y, Muto, Y, Watanabe, S, Kim, I, Ito, T, Nishiya, Y, Sakamoto, K, Ohtsuki, T, Kawai, G, Watanabe, K, Hosono, K, Takaku, H, Katoh, E, Yamazaki, T, Inoue, T, Yokoyama, S. | Deposit date: | 2001-09-27 | Release date: | 2002-05-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intron. RNA, 8, 2002
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6IZP
| Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad | Descriptor: | 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER) | Authors: | Nagano, K, Shibata, T, Nakatani, K, Kawai, G. | Deposit date: | 2018-12-20 | Release date: | 2019-12-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model Nat Commun, 12, 2021
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1L1W
| NMR structure of a SRP19 binding domain in human SRP RNA | Descriptor: | SRP19 binding domain of SRP RNA | Authors: | Sakamoto, T, Morita, S, Tabata, K, Nakamura, K, Kawai, G. | Deposit date: | 2002-02-20 | Release date: | 2002-05-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a SRP19 binding domain in human SRP RNA. J.Biochem.(Tokyo), 132, 2002
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8I43
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8I44
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8I46
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8I45
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1FNX
| SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT | Descriptor: | AU-RICH RNA ELEMENT, HU ANTIGEN C | Authors: | Inoue, M, Hirao, M, Kasashima, K, Kim, I.-S, Kawai, G, Kigawa, T, Sakamoto, H, Muto, Y, Yokoyama, S. | Deposit date: | 2000-08-24 | Release date: | 2003-06-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of mouse HuC RNA-binding domains complexed with an AU-Rich element reveals determinants of neuronal differentiation To be Published, 2000
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1IT1
| Solution structures of ferrocytochrome c3 from Desulfovibrio vulgaris Miyazaki F | Descriptor: | HEME C, cytochrome c3 | Authors: | Harada, E, Fukuoka, Y, Ohmura, T, Fukunishi, A, Kawai, G, Fujiwara, T, Akutsu, H. | Deposit date: | 2001-12-29 | Release date: | 2002-07-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Redox-coupled conformational alternations in cytochrome c(3) from D. vulgaris Miyazaki F on the basis of its reduced solution structure. J.Mol.Biol., 319, 2002
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8K8B
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7FGT
| Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA) | Descriptor: | DNA (5'-D(*AP*AP*GP*AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*CP*TP*T)-3'), ~{N}-[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]-1-methyl-4-[3-[[1-methyl-4-[[1-methyl-4-[3-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazole-2-carboxamide | Authors: | Takase, N, Kawai, G, Igarashi, W, Katagiri, T. | Deposit date: | 2021-07-28 | Release date: | 2022-08-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA) To be published
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7EXY
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8JHP
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7FJ0
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7FHI
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2YRW
| Crystal structure of GAR synthetase from Geobacillus kaustophilus | Descriptor: | PHOSPHATE ION, Phosphoribosylglycinamide synthetase | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-03 | Release date: | 2007-10-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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