7FGT

Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)

Summary for 7FGT

• Entry DOI: 10.2210/pdb7fgt/pdb
• Related PRD ID: PRD_002367
• Descriptor: DNA (5'-D(*AP*AP*GP*AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*CP*TP*T)-3'), ~{N}-[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]-1-methyl-4-[3-[[1-methyl-4-[[1-methyl-4-[3-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazole-2-carboxamide (3 entities in total)
• Functional Keywords: friedreich's ataxia pip, dna
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 6383.63

Authors

Takase, N.,Kawai, G.,Igarashi, W.,Katagiri, T. (deposition date: 2021-07-28, release date: 2022-08-03, Last modification date: 2023-06-14)

• Primary citation: Igarashi, W.,Takase, N.,Kawai, G.,Katagiri, T.; Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA); To be published,

Experimental method

SOLUTION NMR