Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8SRX
DownloadVisualize
BU of 8srx by Molmil
Crystal structure of BAK-BAX heterodimer with lysoPC
Descriptor: 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2 homologous antagonist/killer, ...
Authors:Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S.
Deposit date:2023-05-07
Release date:2023-12-27
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
8SRY
DownloadVisualize
BU of 8sry by Molmil
Crystal structure of BAK-BAX heterodimer with C12E8
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, ...
Authors:Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S.
Deposit date:2023-05-08
Release date:2023-12-27
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
6LG9
DownloadVisualize
BU of 6lg9 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2143
Descriptor: 2-azanyl-7-bromanyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG8
DownloadVisualize
BU of 6lg8 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2138
Descriptor: 2-azanyl-5-fluoranyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y, Zhang, H.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
7U72
DownloadVisualize
BU of 7u72 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U76
DownloadVisualize
BU of 7u76 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 300s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*())-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U74
DownloadVisualize
BU of 7u74 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 30s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U75
DownloadVisualize
BU of 7u75 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 90s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7C
DownloadVisualize
BU of 7u7c by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7J
DownloadVisualize
BU of 7u7j by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 300s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7W
DownloadVisualize
BU of 7u7w by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 1.0 mM Mg2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7A
DownloadVisualize
BU of 7u7a by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 200s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7D
DownloadVisualize
BU of 7u7d by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 30s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U78
DownloadVisualize
BU of 7u78 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 80s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7F
DownloadVisualize
BU of 7u7f by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 90s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7R
DownloadVisualize
BU of 7u7r by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex:no Me2+ soaking
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7Y
DownloadVisualize
BU of 7u7y by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.06 mM Mn2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7T
DownloadVisualize
BU of 7u7t by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.05 mM Mg2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U80
DownloadVisualize
BU of 7u80 by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.25 mM Mn2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7K
DownloadVisualize
BU of 7u7k by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 600s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7E
DownloadVisualize
BU of 7u7e by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 60s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7L
DownloadVisualize
BU of 7u7l by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s with flipped-out product
Descriptor: DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7Z
DownloadVisualize
BU of 7u7z by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.12 mM Mn2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7X
DownloadVisualize
BU of 7u7x by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 2.0 mM Mg2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U83
DownloadVisualize
BU of 7u83 by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 3.0 mM Mn2+ for 600s
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-03-07
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022

227111

数据于2024-11-06公开中

PDB statisticsPDBj update infoContact PDBjnumon