5CU3
 
 | | Crystal structure of CK2alpha bound to CAM4066 | | Descriptor: | ACETATE ION, Casein kinase II subunit alpha, DIMETHYL SULFOXIDE, ... | | Authors: | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | | Deposit date: | 2015-07-24 | | Release date: | 2016-07-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.787 Å) | | Cite: | Specific inhibition of CK2 alpha from an anchor outside the active site.
Chem Sci, 7, 2016
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5CSH
 | | Crystal Structure of CK2alpha with Compound 4 bound | | Descriptor: | 1-(2-chlorobiphenyl-4-yl)methanamine, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | | Deposit date: | 2015-07-23 | | Release date: | 2016-07-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Specific inhibition of CK2 alpha from an anchor outside the active site.
Chem Sci, 7, 2016
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1L0V
 | | Quinol-Fumarate Reductase with Menaquinol Molecules | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Iverson, T.M, Luna-Chavez, C, Croal, L.R, Cecchini, G, Rees, D.C. | | Deposit date: | 2002-02-13 | | Release date: | 2002-03-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site.
J.Biol.Chem., 277, 2002
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4UEG
 | | Crystal structure of human glycogenin-2 catalytic domain | | Descriptor: | GLYCOGENIN-2, MAGNESIUM ION | | Authors: | Fairhead, M, Strain-Damerell, C, Krojer, T, Froese, D.S, Kopec, J, Nowak, R, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | | Deposit date: | 2014-12-17 | | Release date: | 2014-12-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal Structure of Human Glycogenin-2 Catalytic Domain
To be Published
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8I22
 | | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | | Descriptor: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-13 | | Release date: | 2024-01-17 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.15 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase
Nat.Struct.Mol.Biol., 2025
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3JW1
 | | Crystal Structure of Bovine Pancreatic Ribonuclease Complexed with Uridine-5'-monophosphate at 1.60 A Resolution | | Descriptor: | Ribonuclease pancreatic, URIDINE-5'-MONOPHOSPHATE | | Authors: | Larson, S.B, Day, J.S, Nguyen, C, Cudney, R, Mcpherson, A, Center for High-Throughput Structural Biology (CHTSB) | | Deposit date: | 2009-09-17 | | Release date: | 2009-10-06 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of bovine pancreatic ribonuclease complexed with uridine 5'-monophosphate at 1.60 A resolution.
Acta Crystallogr.,Sect.F, 66, 2010
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2ISY
 | | Crystal structure of the nickel-activated two-domain iron-dependent regulator (IdeR) | | Descriptor: | Iron-dependent repressor ideR, NICKEL (II) ION, PHOSPHATE ION | | Authors: | Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. | | Deposit date: | 2006-10-18 | | Release date: | 2007-02-13 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.955 Å) | | Cite: | Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
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8I35
 | | Acyl-ACP synthetase structure bound to oleic acid | | Descriptor: | Acyl-acyl carrier protein synthetase, OLEIC ACID | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-16 | | Release date: | 2024-01-24 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8I3I
 | | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 | | Descriptor: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-17 | | Release date: | 2024-01-24 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8I6M
 | | Acyl-ACP synthetase structure bound to AMP-C18:1 | | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-28 | | Release date: | 2024-01-31 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8HZX
 | | Acyl-ACP synthetase structure-2 | | Descriptor: | Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-09 | | Release date: | 2024-01-24 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8I51
 | | Acyl-ACP synthetase structure bound to AMP-MC7 | | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-21 | | Release date: | 2024-01-24 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8I49
 | | Acyl-ACP synthetase structure bound to ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-18 | | Release date: | 2024-01-24 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.41 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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8I8D
 | | Acyl-ACP synthetase structure bound to MC7-ACP | | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-02-03 | | Release date: | 2024-02-07 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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2IXQ
 | | The solution structure of the invasive tip complex from Afa-Dr fibrils | | Descriptor: | Afimbrial adhesin AFA-III, Protein AfaD | | Authors: | Cota, E, Jones, C, Simpson, P, Altroff, H, Anderson, K.L, du Merle, L, Guignot, J, Servin, A, Le Bouguenec, C, Mardon, H, Matthews, S. | | Deposit date: | 2006-07-10 | | Release date: | 2006-09-20 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the invasive tip complex from Afa/Dr fibrils.
Mol. Microbiol., 62, 2006
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8I8E
 | | Acyl-ACP synthetase structure bound to C18:1-ACP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl carrier protein, Acyl-acyl carrier protein synthetase, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-02-04 | | Release date: | 2024-02-07 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Nat.Struct.Mol.Biol., 2025
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2J3H
 | | Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Apo form | | Descriptor: | NADP-DEPENDENT OXIDOREDUCTASE P1 | | Authors: | Youn, B, Kim, S.J, Moinuddin, S.G, Lee, C, Bedgar, D.L, Harper, A.R, Davin, L.B, Lewis, N.G, Kang, C. | | Deposit date: | 2006-08-21 | | Release date: | 2006-10-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanistic and Structural Studies of Apoform, Binary, and Ternary Complexes of the Arabidopsis Alkenal Double Bond Reductase at5G16970.
J.Biol.Chem., 281, 2006
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1LQ7
 | | De Novo Designed Protein Model of Radical Enzymes | | Descriptor: | Alpha3W | | Authors: | Dai, Q.-H, Tommos, C, Fuentes, E.J, Blomberg, M, Dutton, P.L, Wand, A.J. | | Deposit date: | 2002-05-09 | | Release date: | 2002-06-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a De Novo Designed Protein Model of Radical Enzymes
J.Am.Chem.Soc., 124, 2002
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2IHD
 | | Crystal structure of Human Regulator of G-protein signaling 8, RGS8 | | Descriptor: | CHLORIDE ION, Regulator of G-protein signaling 8 | | Authors: | Turnbull, A.P, Papagrigoriou, E, Ugochukwu, E, Salah, E, Gileadi, C, Burgess, N, Bhatia, C, Gileadi, O, Bray, J, Elkins, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-09-26 | | Release date: | 2006-11-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5CVH
 | | Crystal Structure of CK2alpha | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Casein kinase II subunit alpha, ... | | Authors: | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | | Deposit date: | 2015-07-26 | | Release date: | 2016-07-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.848 Å) | | Cite: | Specific inhibition of CK2 alpha from an anchor outside the active site.
Chem Sci, 7, 2016
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5CVF
 | | Crystal Structure of CK2alpha with Compound 5 bound | | Descriptor: | 1-[3-chloro-4-(trifluoromethoxy)phenyl]methanamine, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | | Deposit date: | 2015-07-26 | | Release date: | 2016-07-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Specific inhibition of CK2 alpha from an anchor outside the active site.
Chem Sci, 7, 2016
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5D29
 | | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU241 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2~{S})-2-carboxy-5-(oxidanylamino)-5-oxidanylidene-pentyl]benzoic acid, ... | | Authors: | Barinka, C, Novakova, Z, Pavlicek, J. | | Deposit date: | 2015-08-05 | | Release date: | 2016-04-27 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
J.Med.Chem., 59, 2016
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2J91
 | | Crystal structure of Human Adenylosuccinate Lyase in complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, CHLORIDE ION, ... | | Authors: | Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Uppsten, M, Thorsell, A.G, van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P. | | Deposit date: | 2006-11-01 | | Release date: | 2006-11-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Human Adenylosuccinate Lyase
To be Published
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8BHD
 | | N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (Tbxo4 derivative crystal structure) | | Descriptor: | GLYCEROL, Glutamate--tRNA ligase, SULFATE ION, ... | | Authors: | Benas, P, Jaramillo Ponce, J.R, Legrand, P, Frugier, M, Sauter, C. | | Deposit date: | 2022-10-31 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes.
Protein Sci., 32, 2023
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2VN6
 | | The Clostridium cellulolyticum dockerin displays a dual binding mode for its cohesin partner | | Descriptor: | CALCIUM ION, ENDOGLUCANASE A, SCAFFOLDING PROTEIN | | Authors: | Pinheiro, B.A, Prates, J.A.M, Proctor, M.R, Gilbert, H.J, Davies, G.J, Money, V.A, Martinez-Fleites, C, Bayer, E.A, Fontes, C.M.G.A, Fierobe, H.P. | | Deposit date: | 2008-01-31 | | Release date: | 2008-05-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | The Clostridium Cellulolyticum Dockerin Displays a Dual Binding Mode for its Cohesin Partner.
J.Biol.Chem., 283, 2008
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