2IHD

Crystal structure of Human Regulator of G-protein signaling 8, RGS8

Summary for 2IHD

• Entry DOI: 10.2210/pdb2ihd/pdb
• Descriptor: Regulator of G-protein signaling 8, CHLORIDE ION (3 entities in total)
• Functional Keywords: rgs8; rgs; signaling protein, structural genomics, structural genomics consortium, sgc, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 18268.06

Authors

Turnbull, A.P.,Papagrigoriou, E.,Ugochukwu, E.,Salah, E.,Gileadi, C.,Burgess, N.,Bhatia, C.,Gileadi, O.,Bray, J.,Elkins, J.,von Delft, F.,Weigelt, J.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2006-09-26, release date: 2006-11-21, Last modification date: 2023-08-30)

• Primary citation: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

Experimental method

X-RAY DIFFRACTION (1.7 Å)