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4LWO
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BU of 4lwo by Molmil
Crystal structure of PRMT6
Descriptor: Arginine N-methyltransferase, putative
Authors:Zhu, Y, Wang, C, Shi, Y, Teng, M.
Deposit date:2013-07-28
Release date:2014-02-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei
Plos One, 9, 2014
4M51
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BU of 4m51 by Molmil
Crystal structure of amidohydrolase nis_0429 (ser145ala mutant) from nitratiruptor sp. sb155-2
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Amidohydrolase family protein, BENZOIC ACID, ...
Authors:Patskovsky, Y, Toro, R, Gobble, A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-08-07
Release date:2013-09-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes.
Biochemistry, 52, 2013
4M13
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BU of 4m13 by Molmil
Crystal structure of ITK in complex with compound 8 [4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide]
Descriptor: 4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4LWS
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BU of 4lws by Molmil
EsxA : EsxB (SeMet) hetero-dimer from Thermomonospora curvata
Descriptor: ACETATE ION, GLYCEROL, Uncharacterized protein
Authors:Dovala, D.L, Cox, J.S, Stroud, R.M, Rosenberg, O.S.
Deposit date:2013-07-28
Release date:2015-02-04
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
4M0Z
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BU of 4m0z by Molmil
Crystal structure of ITK in complex with compound 5 {4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide}
Descriptor: 4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M12
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BU of 4m12 by Molmil
Crystal structure of ITK in complex with compound 7 [4-(carbamoylamino)-1-(7-ethoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide]
Descriptor: 4-(carbamoylamino)-1-(7-ethoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4MBJ
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BU of 4mbj by Molmil
Human B-Raf Kinase Domain in Complex with an Imidazopyridine-based Inhibitor
Descriptor: 2,6-difluoro-N-(1H-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf
Authors:Voegtli, W.C.
Deposit date:2013-08-19
Release date:2013-10-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase.
Bioorg.Med.Chem.Lett., 23, 2013
4MKI
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BU of 4mki by Molmil
Cobalt transporter ATP-binding subunit
Descriptor: DODECYL-BETA-D-MALTOSIDE, Energy-coupling factor transporter ATP-binding protein EcfA2, SULFATE ION
Authors:Yu, Y, Zhang, L, Chai, C.L, Heymann, D.
Deposit date:2013-09-05
Release date:2013-10-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for a homodimeric ATPase subunit of an ECF transporter
Protein Cell, 4, 2013
5H5Z
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BU of 5h5z by Molmil
Crystal structure of bony fish MHC class I, peptide and B2m II
Descriptor: Beta-2-microglobulin, MHC class I antigen, peptide chain
Authors:Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C.
Deposit date:2016-11-10
Release date:2017-11-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish.
Iscience, 23, 2020
4MWH
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BU of 4mwh by Molmil
Crystal structure of scCK2 alpha in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Casein kinase II subunit alpha, MAGNESIUM ION, ...
Authors:Liu, H.
Deposit date:2013-09-24
Release date:2013-11-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4NUX
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BU of 4nux by Molmil
Structure of receptor A
Descriptor: Interleukin-17 receptor A
Authors:Zhang, B, Han, Y, Deng, J.
Deposit date:2013-12-04
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved alpha-helix for Act1 binding and IL-17 signaling.
Acta Crystallogr.,Sect.D, 70, 2014
7VOJ
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BU of 7voj by Molmil
Al-bound structure of the AtALMT1 mutant M60A
Descriptor: ACETIC ACID, ALUMINUM ION, Aluminum-activated malate transporter 1
Authors:Wang, J.
Deposit date:2021-10-14
Release date:2021-12-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.
Cell Res., 32, 2022
7VQ3
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BU of 7vq3 by Molmil
The apo-state AtALMT1 structures at pH 5 (ALMT1apo/pH5)
Descriptor: Aluminum-activated malate transporter 1
Authors:Wang, J.Q.
Deposit date:2021-10-19
Release date:2021-12-01
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.
Cell Res., 32, 2022
7VQ4
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BU of 7vq4 by Molmil
The apo-state AtALMT1 structure at pH 7.5(ALMT1apo/pH7.5)
Descriptor: Aluminum-activated malate transporter 1
Authors:Wang, J.Q.
Deposit date:2021-10-19
Release date:2021-12-01
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.
Cell Res., 32, 2022
7VQ7
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BU of 7vq7 by Molmil
The Al-bound AtALMT1 structure at pH 5 (ALMT1Al/pH5)
Descriptor: ALUMINUM ION, Aluminum-activated malate transporter 1
Authors:Wang, J.Q.
Deposit date:2021-10-19
Release date:2021-12-01
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.
Cell Res., 32, 2022
7VQ5
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BU of 7vq5 by Molmil
The malate-bound AtALMT1 structure at pH 7.5 (ALMT1malate/pH7.5)
Descriptor: (2S)-2-hydroxybutanedioic acid, Aluminum-activated malate transporter 1
Authors:Wang, J.Q.
Deposit date:2021-10-19
Release date:2021-12-01
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.
Cell Res., 32, 2022
7VCF
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BU of 7vcf by Molmil
Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
Descriptor: 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wu, J, Yan, Z, Jin, Z, Zhang, Y.
Deposit date:2021-09-02
Release date:2022-11-30
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Cell, 185, 2022
4LYA
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BU of 4lya by Molmil
EssC (ATPases 2 and 3) from Geobacillus thermodenitrificans (SeMet)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein
Authors:Dovala, D.L, Bendebury, A, Cox, J.S, Stroud, R.M, Rosenberg, O.S.
Deposit date:2013-07-30
Release date:2015-02-04
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
4M14
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BU of 4m14 by Molmil
Crystal structure of ITK in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide]
Descriptor: 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M15
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BU of 4m15 by Molmil
Crystal structure of ITK in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide] and ADP
Descriptor: 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
6K2Z
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BU of 6k2z by Molmil
Human Galectin-14 with lactose
Descriptor: Placental protein 13-like, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.
Deposit date:2019-05-15
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-function studies of galectin-14, an important effector molecule in embryology.
Febs J., 288, 2021
7XK2
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BU of 7xk2 by Molmil
Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex
Descriptor: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, DiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J.
Deposit date:2022-04-19
Release date:2023-02-22
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
4OK6
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BU of 4ok6 by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 13 [[1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid]
Descriptor: CALCIUM ION, Serine protease NS3, [1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
4OK3
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BU of 4ok3 by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 7 [[1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid]
Descriptor: CALCIUM ION, Serine protease NS3, [1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
8Z8Z
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BU of 8z8z by Molmil
Cryo-EM structure of LYCHOS
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Xiong, Q, Zhu, Z, Li, T, Zhou, Z, Chao, Y, Qu, Q, Li, D.
Deposit date:2024-04-22
Release date:2025-01-01
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Molecular architecture of human LYCHOS involved in lysosomal cholesterol signaling.
Nat.Struct.Mol.Biol., 32, 2025

238582

数据于2025-07-09公开中

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