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7DSQ
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BU of 7dsq by Molmil
Overall structure of the LAT1-4F2hc bound with 3,5-diiodo-L-tyrosine
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIIODOTYROSINE, ...
Authors:Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q.
Deposit date:2020-12-31
Release date:2021-03-10
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
Cell Discov, 7, 2021
7DSN
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BU of 7dsn by Molmil
Overall structure of the LAT1-4F2hc bound with JX-119
Descriptor: (2~{S})-2-azanyl-7-[[2-(1,3-benzoxazol-2-yl)phenyl]methoxy]-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q.
Deposit date:2020-12-31
Release date:2021-03-10
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
Cell Discov, 7, 2021
7DSK
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BU of 7dsk by Molmil
Overall structure of the LAT1-4F2hc bound with JX-075
Descriptor: (2~{S})-2-azanyl-7-(naphthalen-1-ylmethoxy)-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q.
Deposit date:2020-12-31
Release date:2021-03-10
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
Cell Discov, 7, 2021
8QNZ
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BU of 8qnz by Molmil
Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem
Descriptor: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1-BUTANOL, BROMIDE ION, ...
Authors:Zhou, Q, He, Y, Jin, Y.
Deposit date:2023-09-27
Release date:2023-11-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity.
Acs Cent.Sci., 9, 2023
3JCT
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BU of 3jct by Molmil
Cryo-em structure of eukaryotic pre-60S ribosomal subunits
Descriptor: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N.
Deposit date:2016-03-09
Release date:2016-06-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
7PGO
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BU of 7pgo by Molmil
Crystal Structure of a Class D Carbapenemase_R250A
Descriptor: 1-BUTANOL, BROMIDE ION, Beta-lactamase
Authors:Zhou, Q, He, Y, Jin, Y.
Deposit date:2021-08-15
Release date:2022-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity
Acs Cent.Sci., 2023
5D6P
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BU of 5d6p by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, DNA gyrase subunit B, ...
Authors:Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
Deposit date:2015-08-12
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5D6Q
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BU of 5d6q by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, DNA gyrase subunit B, ...
Authors:Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
Deposit date:2015-08-12
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5C2Y
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BU of 5c2y by Molmil
Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription)
Descriptor: GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ...
Authors:Yogesha, S.D, Irani, S, Zhang, Y.J.
Deposit date:2015-06-16
Release date:2016-05-04
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
5D7C
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BU of 5d7c by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, DNA gyrase subunit B, ...
Authors:Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
Deposit date:2015-08-13
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
1P9G
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BU of 1p9g by Molmil
Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution
Descriptor: ACETATE ION, EAFP 2
Authors:Xiang, Y, Huang, R.H, Liu, X.Z, Wang, D.C.
Deposit date:2003-05-12
Release date:2004-06-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (0.84 Å)
Cite:Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution.
J.Struct.Biol., 148, 2004
5J8V
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BU of 5j8v by Molmil
Structure of rabbit ryanodine receptor RyR1 open state activated by calcium ion
Descriptor: Ryanodine receptor 1
Authors:Wang, X, Wei, R, Yin, C, Sun, F.
Deposit date:2016-04-08
Release date:2016-09-14
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1
Cell Res., 26, 2016
8Z99
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BU of 8z99 by Molmil
Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state +I
Descriptor: RNA (49-MER), RNA (54-MER), ZINC ION, ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-04-22
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8YHD
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BU of 8yhd by Molmil
Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state I
Descriptor: RNA (35-MER), RNA (53-MER), ZINC ION, ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-02-28
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8Z9C
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BU of 8z9c by Molmil
Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state I
Descriptor: Protein structure, RNA (41-MER), RNA (48-MER), ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-04-23
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8Z4L
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BU of 8z4l by Molmil
Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state I
Descriptor: RNA (40-MER), RNA (49-MER), ZINC ION, ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-04-17
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8YHE
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BU of 8yhe by Molmil
Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state II
Descriptor: RNA (29-MER), RNA (46-MER), ZINC ION, ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-02-28
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8Z4J
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BU of 8z4j by Molmil
Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state II
Descriptor: Protein structure, RNA (34-MER), RNA (38-MER), ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-04-17
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
8Z9E
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BU of 8z9e by Molmil
Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state II
Descriptor: Protein structure, RNA (34-MER), RNA (39-MER), ...
Authors:Zhang, H, Deng, Z, Li, X.
Deposit date:2024-04-23
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 2024
5LG4
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BU of 5lg4 by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.9 angstrom resolution
Descriptor: Exocyst complex component SEC3, Protein SSO2, SULFATE ION
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-07-05
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
8HIF
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BU of 8hif by Molmil
One asymmetric unit of Singapore grouper iridovirus capsid
Descriptor: Major capsid protein, Penton protein (VP14), VP137, ...
Authors:Zhao, Z.N, Liu, C.C, Zhu, D.J, Qi, J.X, Zhang, X.Z, Gao, G.F.
Deposit date:2022-11-20
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly.
Nat Commun, 14, 2023
4FF5
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BU of 4ff5 by Molmil
Structure basis of a novel virulence factor GHIP a glycosyl hydrolase 25 of Streptococcus pneumoniae participating in host cell invasion
Descriptor: 1,2-ETHANEDIOL, Glycosyl hydrolase 25
Authors:Wang, D.
Deposit date:2012-05-31
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.
Plos One, 8, 2013
7LRS
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BU of 7lrs by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
Descriptor: Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, antibody A23-58.1 heavy chain, ...
Authors:Zhou, T, Tsybovsky, Y.
Deposit date:2021-02-17
Release date:2021-07-14
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
5M4Y
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BU of 5m4y by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.20 angstrom resolution
Descriptor: Exocyst complex component SEC3, GLYCEROL, Protein SSO2
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-10-19
Release date:2017-02-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
1FPL
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BU of 1fpl by Molmil
FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND THALLIUM IONS (10 MM)
Descriptor: 2,5-anhydro-1,6-di-O-phosphono-D-glucitol, ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE, ...
Authors:Villeret, V, Lipscomb, W.N.
Deposit date:1995-06-02
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995

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数据于2024-09-04公开中

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