7YK7
| Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | Authors: | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Xu, H.E, Yang, D.H, Liu, H, Wang, M.W. | Deposit date: | 2022-07-21 | Release date: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14, 2023
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5E9U
| Crystal structure of GtfA/B complex bound to UDP and GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, ... | Authors: | Chen, Y, Rapoport, T.A. | Deposit date: | 2015-10-15 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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5E9T
| Crystal structure of GtfA/B complex | Descriptor: | Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, MAGNESIUM ION | Authors: | Chen, Y, Rapoport, T.A. | Deposit date: | 2015-10-15 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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6K28
| Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE | Descriptor: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION | Authors: | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | Deposit date: | 2019-05-13 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae. Biochem.Biophys.Res.Commun., 518, 2019
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6JYY
| Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia | Descriptor: | Hydroxyethylthiazole kinase | Authors: | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | Deposit date: | 2019-04-29 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae. Biochem.Biophys.Res.Commun., 518, 2019
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5FX8
| Complete structure of manganese lipoxygenase of Gaeumannomyces graminis and partial structure of zonadhesin of Komagataella pastoris | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, Y, Wennman, A, Karkehanadi, S, Engstrom, A, Oliw, E.H. | Deposit date: | 2016-02-25 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Linoleate 13R-Manganese Lipoxygenase and an Adhesion Protein J.Lipid Res., 57, 2016
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6KOR
| Crystal structure of the RRM domain of SYNCRIP | Descriptor: | Heterogeneous nuclear ribonucleoprotein Q | Authors: | Chen, Y, Chan, J, Chen, W, Jobichen, C. | Deposit date: | 2019-08-12 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | SYNCRIP, a new player in pri-let-7a processing. Rna, 26, 2020
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7DDC
| Crystal structure of SARS-CoV-2 main protease in complex with Tafenoquine | Descriptor: | 3C-like proteinase, Tafenoquine | Authors: | Chen, Y, Wang, Y.C, Yang, C.S, Hung, M.C. | Deposit date: | 2020-10-28 | Release date: | 2021-11-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.175 Å) | Cite: | Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2. J.Biol.Chem., 298, 2022
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6KZW
| Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum | Descriptor: | PHOSPHATE ION, Pyridoxal phosphate homeostasis protein | Authors: | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | Deposit date: | 2019-09-25 | Release date: | 2019-10-16 | Last modified: | 2021-01-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum To Be Published
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5X8F
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5X8G
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7FJF
| Cryo-EM structure of a membrane protein(CS) | Descriptor: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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7FJE
| Cryo-EM structure of a membrane protein(LL) | Descriptor: | CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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7FJD
| Cryo-EM structure of a membrane protein(WT) | Descriptor: | CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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7WVI
| Crystal structure of SIA28 | Descriptor: | Heavy chain of SIA28, Light chain of SIA28 | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7WVG
| Crystal structure of H18 complexed with SIA28 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7WVD
| Crystal structure of H14 complexed with SIA28 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7CVH
| Human Fructose-1,6-bisphosphatase 1 in complex with geranylgeranyl diphosphate | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | Authors: | Chen, Y, Zhang, J, Li, C, Cao, Y. | Deposit date: | 2020-08-26 | Release date: | 2021-09-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The structural basis for GGPP activation on the enzymatic activities FBP1 To Be Published
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7D1G
| Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii | Descriptor: | BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION | Authors: | Chen, Y, Lan, J, Liu, W, Wang, L, Xu, Y. | Deposit date: | 2020-09-14 | Release date: | 2021-03-17 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii To Be Published
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7WVB
| Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state | Descriptor: | Fructose-1,6-bisphosphatase 1 | Authors: | Chen, Y, Zhang, J, Li, C, Cao, Y. | Deposit date: | 2022-02-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state To Be Published
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7UL1
| Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing IGHV3-53-encoded antibody EH3 isolated from a nonvaccinated pediatric patient | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH3, Light chain of EH3, ... | Authors: | Chen, Y, Tolbert, W.D, Pazgier, M. | Deposit date: | 2022-04-03 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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7UL0
| Crystal structure of SARS-CoV-2 RBD in complex with the ridge-binding nAb EH8 isolated from a nonvaccinated pediatric patient | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH8, ... | Authors: | Chen, Y, Tolbert, W.D, Bai, X, Pazgier, M. | Deposit date: | 2022-04-03 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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7D54
| Crstal structure MsGATase with Gln | Descriptor: | GLUTAMINE, Glutamine amidotransferase class-I | Authors: | Chen, Y, Zhang, Q, Bartlam, M. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and mechanism of the gamma-glutamyl-gamma-aminobutyrate hydrolase SpuA from Pseudomonas aeruginosa. Acta Crystallogr D Struct Biol, 77, 2021
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7D53
| SpuA mutant - H221N with Glu | Descriptor: | GLUTAMIC ACID, MAGNESIUM ION, Probable glutamine amidotransferase | Authors: | Chen, Y, Zhang, Q, Bartlam, M. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and mechanism of the gamma-glutamyl-gamma-aminobutyrate hydrolase SpuA from Pseudomonas aeruginosa. Acta Crystallogr D Struct Biol, 77, 2021
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7D4R
| SpuA native structure | Descriptor: | MAGNESIUM ION, Probable glutamine amidotransferase | Authors: | Chen, Y, Zhang, Q, Bartlam, M. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and mechanism of the gamma-glutamyl-gamma-aminobutyrate hydrolase SpuA from Pseudomonas aeruginosa. Acta Crystallogr D Struct Biol, 77, 2021
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