2G3R
| Crystal Structure of 53BP1 tandem tudor domains at 1.2 A resolution | Descriptor: | SULFATE ION, Tumor suppressor p53-binding protein 1 | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | Deposit date: | 2006-02-20 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127, 2006
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2FHD
| Crystal structure of Crb2 tandem tudor domains | Descriptor: | DNA repair protein rhp9/CRB2, PHOSPHATE ION | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | Deposit date: | 2005-12-23 | Release date: | 2007-01-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell(Cambridge,Mass.), 127, 2006
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3Q66
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3SZM
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5UMR
| Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 | Descriptor: | FACT complex subunit SSRP1 | Authors: | Su, D, Hu, Q, Thompson, J.R, Heroux, A, Botuyan, M.V, Mer, G. | Deposit date: | 2017-01-29 | Release date: | 2018-01-31 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 To Be Published
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8UPF
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168-UbcH5c | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-10-22 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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5UMS
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3U3Z
| Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142 | Descriptor: | GLYCEROL, Histone H2A.X peptide, Microcephalin | Authors: | Singh, N, Thompson, J.R, Heroux, A, Mer, G. | Deposit date: | 2011-10-06 | Release date: | 2012-07-25 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proc.Natl.Acad.Sci.USA, 109, 2012
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5UMU
| Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 | Descriptor: | ACETATE ION, FACT complex subunit SPT16, FORMIC ACID | Authors: | Hu, Q, Thompson, J.R, Heroux, A, Su, D, Botuyan, M.V, Mer, G. | Deposit date: | 2017-01-29 | Release date: | 2018-01-31 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 To Be Published
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5UMT
| Crystal structure of N-terminal domain of human FACT complex subunit SPT16 | Descriptor: | 1,2-ETHANEDIOL, FACT complex subunit SPT16, GLYCEROL | Authors: | Su, D, Hu, Q, Thompson, J.R, Botuyan, M.V, Mer, G. | Deposit date: | 2017-01-29 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.092 Å) | Cite: | Crystal structure of N-terminal domain of human FACT complex subunit SPT16 To Be Published
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8TXV
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-08-24 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8TXX
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-08-24 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8TXW
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-08-24 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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3Q68
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5VWE
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2QQR
| JMJD2A hybrid tudor domains | Descriptor: | JmjC domain-containing histone demethylation protein 3A, SULFATE ION | Authors: | Lee, J, Botuyan, M.V, Mer, G. | Deposit date: | 2007-07-26 | Release date: | 2007-12-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15, 2008
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3T1N
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2QQS
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3PA6
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2LH0
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2L0G
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2L0F
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2LVM
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2K2W
| Second BRCT domain of NBS1 | Descriptor: | Recombination and DNA repair protein | Authors: | Xu, C, Cui, G, Botuyan, M, Mer, G. | Deposit date: | 2008-04-14 | Release date: | 2008-06-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. J.Mol.Biol., 381, 2008
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2LY1
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