4KXV
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![BU of 4kxv by Molmil](/molmil-images/mine/4kxv) | Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, D-XYLITOL-5-PHOSPHATE, ... | Authors: | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | Deposit date: | 2013-05-28 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
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3OE1
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![BU of 3oe1 by Molmil](/molmil-images/mine/3oe1) | Pyruvate decarboxylase variant Glu473Asp from Z. mobilis in complex with reaction intermediate 2-lactyl-ThDP | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, GLYCEROL, MAGNESIUM ION, ... | Authors: | Meyer, D, Neumann, P, Parthier, C, Tittmann, K. | Deposit date: | 2010-08-12 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.985 Å) | Cite: | Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate . Biochemistry, 49, 2010
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2JNR
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![BU of 2jnr by Molmil](/molmil-images/mine/2jnr) | Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | Descriptor: | ENV polyprotein, VIR165 | Authors: | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | Deposit date: | 2007-02-01 | Release date: | 2007-05-08 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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1DIP
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![BU of 1dip by Molmil](/molmil-images/mine/1dip) | THE SOLUTION STRUCTURE OF PORCINE DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE, NMR, 10 STRUCTURES | Descriptor: | DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE | Authors: | Roesch, P, Seidel, G, Adermann, K, Schindler, T, Ejchart, A, Jaenicke, R, Forssmann, W.G. | Deposit date: | 1997-04-09 | Release date: | 1997-10-15 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine delta sleep-inducing peptide immunoreactive peptide A homolog of the shortsighted gene product. J.Biol.Chem., 272, 1997
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7OIY
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![BU of 7oiy by Molmil](/molmil-images/mine/7oiy) | Crystal structure of the ZUFSP family member Mug105 | Descriptor: | SODIUM ION, Ubiquitin carboxyl-terminal hydrolase mug105 | Authors: | Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2021-05-12 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
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7OJE
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![BU of 7oje by Molmil](/molmil-images/mine/7oje) | Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ... | Authors: | Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2021-05-14 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
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4ZP1
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![BU of 4zp1 by Molmil](/molmil-images/mine/4zp1) | Crystal structure of Zymomonas mobilis pyruvate decarboxylase variant Glu473Ala | Descriptor: | GLYCEROL, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Wechsler, C, Neumann, P, Tittmann, K. | Deposit date: | 2015-05-07 | Release date: | 2015-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.205 Å) | Cite: | Tuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot Spot. Chembiochem, 16, 2015
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1B89
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![BU of 1b89 by Molmil](/molmil-images/mine/1b89) | CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) | Descriptor: | PROTEIN (CLATHRIN HEAVY CHAIN) | Authors: | Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K. | Deposit date: | 1999-05-27 | Release date: | 1999-06-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature, 399, 1999
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1BWX
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![BU of 1bwx by Molmil](/molmil-images/mine/1bwx) | THE SOLUTION STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 1-39, NMR, 10 STRUCTURES | Descriptor: | PARATHYROID HORMONE | Authors: | Marx, U.C, Roesch, P, Adermann, K, Bayer, P, Forssmann, W.-G. | Deposit date: | 1998-09-29 | Release date: | 2000-01-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37). Biochem.Biophys.Res.Commun., 267, 2000
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1UYA
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![BU of 1uya by Molmil](/molmil-images/mine/1uya) | THE SOLUTION STRUCTURE OF THE A-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES | Descriptor: | UROGUANYLIN-16, ISOMER A | Authors: | Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P. | Deposit date: | 1997-09-11 | Release date: | 1998-03-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers. J.Pept.Res., 52, 1998
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1UYB
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![BU of 1uyb by Molmil](/molmil-images/mine/1uyb) | THE SOLUTION STRUCTURE OF THE B-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES | Descriptor: | UROGUANYLIN-16, ISOMER B | Authors: | Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P. | Deposit date: | 1997-09-11 | Release date: | 1998-03-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers. J.Pept.Res., 52, 1998
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6YI1
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![BU of 6yi1 by Molmil](/molmil-images/mine/6yi1) | Crystal structure of human glutaminyl cyclase in complex with Glu(gamma-hydrazide)-Phe-Ala | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kupski, O, Sautner, V, Tittmann, K. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. Biochemistry, 59, 2020
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8ADD
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![BU of 8add by Molmil](/molmil-images/mine/8add) | Viral tegument-like DUBs | Descriptor: | ATP-dependent DNA helicase | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
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6YR3
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![BU of 6yr3 by Molmil](/molmil-images/mine/6yr3) | |
6YRH
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![BU of 6yrh by Molmil](/molmil-images/mine/6yrh) | |
6YRT
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![BU of 6yrt by Molmil](/molmil-images/mine/6yrt) | |
6YS0
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![BU of 6ys0 by Molmil](/molmil-images/mine/6ys0) | |
6YRE
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![BU of 6yre by Molmil](/molmil-images/mine/6yre) | Transaldolase variant T30C/D211C from T. acidophilum | Descriptor: | ACETATE ION, GLYCEROL, Probable transaldolase | Authors: | Sautner, V, Lietzow, T.H, Tittmann, K. | Deposit date: | 2020-04-20 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release To Be Published
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6YRM
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6ZWJ
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![BU of 6zwj by Molmil](/molmil-images/mine/6zwj) | Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution | Descriptor: | CITRIC ACID, GLYCEROL, Transaldolase | Authors: | Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZWF
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![BU of 6zwf by Molmil](/molmil-images/mine/6zwf) | Neisseria gonorrhoeae transaldolase | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ... | Authors: | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZWH
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![BU of 6zwh by Molmil](/molmil-images/mine/6zwh) | Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | Authors: | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | Deposit date: | 2020-07-28 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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6ZX4
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![BU of 6zx4 by Molmil](/molmil-images/mine/6zx4) | Neisseria gonorrhoeae transaldolase | Descriptor: | CITRIC ACID, GLYCEROL, Transaldolase | Authors: | Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K. | Deposit date: | 2020-07-29 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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3OC4
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![BU of 3oc4 by Molmil](/molmil-images/mine/3oc4) | Crystal Structure of a pyridine nucleotide-disulfide family oxidoreductase from the Enterococcus faecalis V583 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Oxidoreductase, pyridine nucleotide-disulfide family, ... | Authors: | Kumaran, D, Baumann, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-08-09 | Release date: | 2010-10-06 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of a pyridine nucleotide-disulfide family oxidoreductase from the Enterococcus faecalis V583 To be Published
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7B0L
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![BU of 7b0l by Molmil](/molmil-images/mine/7b0l) | |