7NDK
 
 | | Crystal structure of ZC3H12C PIN catalytic mutant | | Descriptor: | Probable ribonuclease ZC3H12C, SODIUM ION | | Authors: | Garg, A, Heinemann, U. | | Deposit date: | 2021-02-01 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
|
|
7NDH
 | | Crystal structure of ZC3H12C PIN domain | | Descriptor: | 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, SODIUM ION | | Authors: | Garg, A, Heinemann, U. | | Deposit date: | 2021-02-01 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
|
|
2IW2
 | | Crystal structure of human Prolidase | | Descriptor: | SODIUM ION, XAA-PRO DIPEPTIDASE | | Authors: | Mueller, U, Niesen, F.H, Roske, Y, Goetz, F, Behlke, J, Buessow, K, Heinemann, U. | | Deposit date: | 2006-06-24 | | Release date: | 2006-07-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Crystal Structure of Human Prolidase: The Molecular Basis of Pd Disease
To be Published
|
|
2JJZ
 | | Crystal Structure of Human Iba2, orthorhombic crystal form | | Descriptor: | ACETATE ION, CHLORIDE ION, IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2, ... | | Authors: | Schulze, J.O, Quedenau, C, Roske, Y, Turnbull, A, Mueller, U, Heinemann, U, Buessow, K. | | Deposit date: | 2008-05-15 | | Release date: | 2009-07-14 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and Functional Characterization of Human Iba Proteins.
FEBS J., 275, 2008
|
|
6Q3V
 | |
3TH0
 | | P22 Tailspike complexed with S.Paratyphi O antigen octasaccharide | | Descriptor: | Bifunctional tail protein, GLYCEROL, alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose | | Authors: | Andres, D, Gohlke, U, Heinemann, U, Seckler, R, Barbirz, S. | | Deposit date: | 2011-08-18 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Glycobiology, 23, 2013
|
|
1ONI
 | | Crystal structure of a human p14.5, a translational inhibitor reveals different mode of ligand binding near the invariant residues of the Yjgf/UK114 protein family | | Descriptor: | 14.5 kDa translational inhibitor protein, BENZOIC ACID | | Authors: | Manjasetty, B.A, Delbrueck, H, Mueller, U, Erdmann, M.F, Heinemann, U. | | Deposit date: | 2003-02-28 | | Release date: | 2003-04-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of Homo sapiens protein hp14.5.
Proteins, 54, 2004
|
|
1NEG
 | | Crystal Structure Analysis of N-and C-terminal labeled SH3-domain of alpha-Chicken Spectrin | | Descriptor: | AZIDE ION, Spectrin alpha chain, brain | | Authors: | Mueller, U, Buessow, K, Diehl, A, Niesen, F.H, Nyarsik, L, Heinemann, U. | | Deposit date: | 2002-12-11 | | Release date: | 2003-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags
J.STRUCT.FUNCT.GENOM., 4, 2003
|
|
1RGL
 | | RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 | | Authors: | Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. | | Deposit date: | 1992-02-19 | | Release date: | 1993-01-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite.
J.Mol.Biol., 225, 1992
|
|
6H0X
 | | Crystal Structure of KDM4D with tetrazolylhydrazide ligand AA040 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... | | Authors: | Malecki, P.H, Weiss, M.S, Heinemann, U, Link, A. | | Deposit date: | 2018-07-10 | | Release date: | 2020-01-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Crystal Structure of KDM4D with tetrazolylhydrazide ligand AA040
To be published
|
|
6H11
 | | Crystal Structure of KDM4D with tetrazolylhydrazide ligand AA028 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... | | Authors: | Malecki, P.H, Weiss, M.S, Heinemann, U, Link, A. | | Deposit date: | 2018-07-10 | | Release date: | 2020-01-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.516 Å) | | Cite: | Crystal Structure of KDM4D with tetrazolylhydrazide ligand AA028
To be published
|
|
6H0W
 | | Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035 | | Descriptor: | (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Malecki, P.H, Weiss, M.S, Heinemann, U, Link, A. | | Deposit date: | 2018-07-10 | | Release date: | 2020-01-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035
To be published
|
|
2XKW
 | | LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST PIOGLITAZONE | | Descriptor: | (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Mueller, J.J, Schupp, M, Unger, T, Kintscher, U, Heinemann, U. | | Deposit date: | 2010-07-14 | | Release date: | 2011-08-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Binding Diversity of Pioglitazone by Peroxisome Proliferator-Activated Receptor-Gamma
To be Published
|
|
6HQC
 | |
3FIL
 | |
122D
 | |
123D
 | |
4ZP3
 | | AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA | | Descriptor: | A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, cAMP-dependent protein kinase type II-alpha regulatory subunit | | Authors: | Goetz, F, Roske, Y, Faelber, K, Zuehlke, K, Autenrieth, K, Kreuchwig, A, Krause, G, Herberg, F.W, Daumke, O, Heinemann, U, Klussmann, E. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Biochem.J., 473, 2016
|
|
5IFW
 | |
3PR6
 | |
5IFS
 | | Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | Authors: | Roske, Y, Arumughan, A, Heinemann, U, Wanker, E. | | Deposit date: | 2016-02-26 | | Release date: | 2016-10-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun, 7, 2016
|
|
1GZU
 | | Crystal Structure of Human Nicotinamide Mononucleotide Adenylyltransferase in Complex with NMN | | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE | | Authors: | Werner, E, Ziegler, M, Lerner, F, Schweiger, M, Heinemann, U. | | Deposit date: | 2002-06-06 | | Release date: | 2002-07-05 | | Last modified: | 2018-06-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN.
FEBS Lett., 516, 2002
|
|
1GPP
 | |
1XCR
 | | Crystal Structure of Longer Splice Variant of PTD012 from Homo sapiens reveals a novel Zinc-containing fold | | Descriptor: | ACETIC ACID, ZINC ION, hypothetical protein PTD012 | | Authors: | Manjasetty, B.A, Fieber-Erdmann, M, Roske, Y, Goetz, F, Buessow, K, Heinemann, U. | | Deposit date: | 2004-09-03 | | Release date: | 2005-09-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold
Protein Sci., 15, 2006
|
|
1RGK
 | | RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE | | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1 | | Authors: | Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. | | Deposit date: | 1992-02-19 | | Release date: | 1993-01-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite.
J.Mol.Biol., 225, 1992
|
|
