3TH0

P22 Tailspike complexed with S.Paratyphi O antigen octasaccharide

Summary for 3TH0

• Entry DOI: 10.2210/pdb3th0/pdb
• Related: 1tyu 1tyv 1tyx
• Descriptor: Bifunctional tail protein, alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose, GLYCEROL, ... (4 entities in total)
• Functional Keywords: viral adhesion protein, receptor, endoglycosidase, carbohydrate, cell receptor, recognition, binding protein lipopolysaccharide, beta helix, host recognition, bacteriophage p22 baseplate, hydrolase, viral protein
• Biological source: Enterobacteria phage P22
• Cellular location: Virion (Potential): P12528
• Total number of polymer chains: 1
• Total formula weight: 61760.70

Authors

Andres, D.,Gohlke, U.,Heinemann, U.,Seckler, R.,Barbirz, S. (deposition date: 2011-08-18, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Andres, D.,Gohlke, U.,Broeker, N.K.,Schulze, S.,Rabsch, W.,Heinemann, U.,Barbirz, S.,Seckler, R.; An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.; Glycobiology, 23:486-494, 2013; PubMed: 23292517; DOI: 10.1093/glycob/cws224

Experimental method

X-RAY DIFFRACTION (1.75 Å)