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6FR9
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BU of 6fr9 by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR7
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BU of 6fr7 by Molmil
HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, T-Cell Receptor alpha chain, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUP
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BU of 6fup by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUQ
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BU of 6fuq by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Human F11 T-Cell Receptor, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR6
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BU of 6fr6 by Molmil
HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101
Descriptor: Human T-Cell Receptor Alpha Chain, Human T-cell Receptor Beta Chain, SULFATE ION
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FRB
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BU of 6frb by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
Descriptor: Human T-Cell Receptor F11 alpha chain, Human T-Cell Receptor F11 beta Chain
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUR
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BU of 6fur by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Human F11 T-Cell Receptor, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
4MJI
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BU of 4mji by Molmil
T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01
Descriptor: Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M.
Deposit date:2013-09-03
Release date:2014-05-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01
J.Immunol., 192, 2014
4QOK
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BU of 4qok by Molmil
Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2014-06-20
Release date:2014-12-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.
Eur.J.Immunol., 45, 2015
4U1I
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BU of 4u1i by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1H
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BU of 4u1h by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1L
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BU of 4u1l by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1J
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BU of 4u1j by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1N
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BU of 4u1n by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1S
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BU of 4u1s by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-16
Release date:2015-04-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1K
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BU of 4u1k by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4Z77
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BU of 4z77 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
To Be Published
4Z76
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BU of 4z76 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
5BS0
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BU of 5bs0 by Molmil
MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K.
Deposit date:2015-06-01
Release date:2016-03-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
4Z78
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BU of 4z78 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
5BRZ
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BU of 5brz by Molmil
MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1
Descriptor: Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ...
Authors:Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K.
Deposit date:2015-06-01
Release date:2016-03-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
3UTS
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BU of 3uts by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Monoclinic
Descriptor: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTT
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BU of 3utt by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Triclinic
Descriptor: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M, Rossjohn, J, Gras, S.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTP
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BU of 3utp by Molmil
1E6 TCR specific for HLA-A*0201-ALWGPDPAAA
Descriptor: 1E6 TCR alpha chain, 1E6 TCR beta chain, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012

238582

数据于2025-07-09公开中

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