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Structure of human KCNQ4-ML213 complex with PIP2
Descriptor:	(1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ...
Authors:	Xu, F, Zheng, Y.
Deposit date:	2021-10-11
Release date:	2021-12-01
Last modified:	2024-06-19
Method:	ELECTRON MICROSCOPY (2.79 Å)
Cite:	Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022

7VCF

Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
Descriptor:	1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:	Wu, J, Yan, Z, Jin, Z, Zhang, Y.
Deposit date:	2021-09-02
Release date:	2022-11-30
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (2.5 Å)
Cite:	Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes. Cell, 185, 2022

7WN0

Structure of PfENT1(Y190A) in complex with nanobody 19
Descriptor:	Equilibrative nucleoside/nucleobase transporter, nanobody19
Authors:	Wang, C, Deng, D, Ren, R.B, Yu, L.Y.
Deposit date:	2022-01-17
Release date:	2023-02-01
Last modified:	2023-08-16
Method:	ELECTRON MICROSCOPY (3.64 Å)
Cite:	Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023

7WN1

Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine
Descriptor:	Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48
Authors:	Wang, C, Deng, D, Ren, R.B, Yu, L.Y.
Deposit date:	2022-01-17
Release date:	2023-02-01
Last modified:	2023-08-16
Method:	ELECTRON MICROSCOPY (3.11 Å)
Cite:	Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023

7C53

Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor:	CALCIUM ION, Spike protein S2',pan-CoVs inhibitor EK1
Authors:	Zhu, Y, Yang, X, Sun, F.
Deposit date:	2020-05-19
Release date:	2021-05-19
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.278 Å)
Cite:	Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation. Signal Transduct Target Ther, 6, 2021

7DMP

Mouse radial spoke complex
Descriptor:	Radial spoke head 1 homolog, Radial spoke head protein 4 homolog A, Radial spoke head protein 9 homolog
Authors:	Zheng, W, Cong, Y.
Deposit date:	2020-12-05
Release date:	2021-07-21
Last modified:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM Proc.Natl.Acad.Sci.USA, 118, 2021

2IYC

SENP1 native structure
Descriptor:	SENTRIN-SPECIFIC PROTEASE 1
Authors:	Dong, C, Naismith, J.H.
Deposit date:	2006-07-14
Release date:	2006-08-08
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Senp1 Native Structure To be Published

2IYD

SENP1 covalent complex with SUMO-2
Descriptor:	SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 2
Authors:	Dong, C, Naismith, J.H.
Deposit date:	2006-07-14
Release date:	2006-08-08
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Senp1 Native Structure To be Published

7E8O

Crystal structure of proteinaceous RNase P(PRORP) from Planctomycetes bacterium GWF2_40_8 complexed with Escherichia coli histidine pre-tRNA
Descriptor:	CALCIUM ION, RNA-free ribonuclease P, histidine pre-tRNA
Authors:	Li, Y.Y, Gan, J.H.
Deposit date:	2021-03-02
Release date:	2022-03-02
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.804 Å)
Cite:	Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. Nat Commun, 13, 2022

7E8K

Crystal structure of Proteinaceous RNase P (PRORP) from Planctomycetes bacterium GWF2_40_8
Descriptor:	RNA-free ribonuclease P, SULFATE ION
Authors:	Li, Y.Y, Gan, J.H.
Deposit date:	2021-03-02
Release date:	2022-03-02
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. Nat Commun, 13, 2022

7E8J

Crystal structure of Proteinaceous RNase P (PRORP) from Thermococcus celer
Descriptor:	RNA-free ribonuclease P
Authors:	Li, Y.Y, Gan, J.H.
Deposit date:	2021-03-02
Release date:	2022-03-02
Last modified:	2024-05-29
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. Nat Commun, 13, 2022

7CRH

Cryo-EM structure of SKF83959 bound dopamine receptor DRD1-Gs signaling complex
Descriptor:	(1S)-6-chloranyl-3-methyl-1-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:	Yan, W, Shao, Z.H.
Deposit date:	2020-08-13
Release date:	2021-03-03
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184, 2021

7CKW

Cryo-EM structure of Fenoldopam bound dopamine receptor DRD1-Gs signaling complex
Descriptor:	(1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:	Yan, W, Shao, W.
Deposit date:	2020-07-20
Release date:	2021-03-03
Method:	ELECTRON MICROSCOPY (3.22 Å)
Cite:	Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184, 2021

7CKZ

Cryo-EM structure of Dopamine and LY3154207 bound dopamine receptor DRD1-Gs signaling complex
Descriptor:	2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:	Yan, W, Shao, Z.
Deposit date:	2020-07-20
Release date:	2021-03-03
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184, 2021

7CKY

Cryo-EM structure of PW0464 bound dopamine receptor DRD1-Gs signaling complex
Descriptor:	6-[4-[3-[bis(fluoranyl)methoxy]pyridin-2-yl]oxy-2-methyl-phenyl]-1,5-dimethyl-pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:	Yan, W, Shao, Z.
Deposit date:	2020-07-20
Release date:	2021-03-03
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184, 2021

7CKX

Cryo-EM structure of A77636 bound dopamine receptor DRD1-Gs signaling complex
Descriptor:	(1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:	Yan, W, Shao, Z.
Deposit date:	2020-07-20
Release date:	2021-03-03
Method:	ELECTRON MICROSCOPY (3.54 Å)
Cite:	Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184, 2021

7C43

The crystal structure of Trypanosoma brucei RNase D : AMP complex
Descriptor:	ADENOSINE MONOPHOSPHATE, CCHC-type domain-containing protein, MANGANESE (II) ION, ...
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-14
Release date:	2021-04-07
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7C4C

The crystal structure of Trypanosoma brucei RNase D : GMP complex
Descriptor:	CCHC-type domain-containing protein, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-15
Release date:	2021-04-07
Method:	X-RAY DIFFRACTION (2.265 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7C4B

The crystal structure of Trypanosoma brucei RNase D : UMP complex
Descriptor:	CCHC-type domain-containing protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-15
Release date:	2021-04-07
Last modified:	2024-05-29
Method:	X-RAY DIFFRACTION (2.101 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7C45

The crystal structure of Trypanosoma brucei RNase D complex with RNA U12
Descriptor:	CALCIUM ION, CCHC-type domain-containing protein, RNA (5'-R(UPUPUPUPUPUPUPUPUPU)-3'), ...
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-15
Release date:	2021-04-07
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (1.769 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7C47

The crystal structure of Trypanosoma brucei RNase D : CMP complex
Descriptor:	CCHC-type domain-containing protein, CYTIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-15
Release date:	2021-04-07
Last modified:	2024-05-29
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7C42

The crystal structure of Trypanosoma brucei RNase D
Descriptor:	CCHC-type domain-containing protein, ZINC ION
Authors:	Gao, Y.Q, Gan, J.H.
Deposit date:	2020-05-14
Release date:	2021-04-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021

7DD1

Crystal structure of SRPK1 in complex with a peptide inhibitor
Descriptor:	ARG-GLU-ARG-ALA-ARG-THR-ARG, SRSF protein kinase 1,SRSF protein kinase 1
Authors:	Li, Q.Y, Yung, K.W.Y, Ngo, J.C.K.
Deposit date:	2020-10-27
Release date:	2021-04-21
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis. Iscience, 24, 2021

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Displayed results:	23
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