7VKK
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![BU of 7vkk by Molmil](/molmil-images/mine/7vkk) | Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION | Authors: | Zhang, T, Ding, J. | Deposit date: | 2021-09-30 | Release date: | 2022-07-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling. Sci Adv, 8, 2022
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7VKR
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7VKQ
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5GYZ
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![BU of 5gyz by Molmil](/molmil-images/mine/5gyz) | luciferase AMP/7-cy-L complex | Descriptor: | (4S)-2-[6-(azepan-1-yl)-1,3-benzothiazol-2-yl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Su, J, Wang, F. | Deposit date: | 2016-09-26 | Release date: | 2017-09-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of luciferase with AMP/7-cy-L at 2.4 Angstroms resolution To Be Published
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4O8C
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![BU of 4o8c by Molmil](/molmil-images/mine/4o8c) | Structure of the H170Y mutant of thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus | Descriptor: | MAGNESIUM ION, SULFATE ION, Thermostable NPPase | Authors: | Shen, T, Guo, Z, Wang, F, Gong, W, Ji, C. | Deposit date: | 2013-12-27 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a His170Tyr mutant of thermostable pNPPase from Geobacillus stearothermophilus. Acta Crystallogr.,Sect.F, 70, 2014
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7E1T
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![BU of 7e1t by Molmil](/molmil-images/mine/7e1t) | Crystal structure of Rab9A-GTP-Nde1 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Isoform 2 of Nuclear distribution protein nudE homolog 1, MAGNESIUM ION, ... | Authors: | Zhang, Y, Zhang, T, Ding, J. | Deposit date: | 2021-02-03 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex. Structure, 30, 2022
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7EPZ
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![BU of 7epz by Molmil](/molmil-images/mine/7epz) | Overall structure of Erastin-bound xCT-4F2hc complex | Descriptor: | 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-04-28 | Release date: | 2022-04-06 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Res., 32, 2022
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4CLC
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![BU of 4clc by Molmil](/molmil-images/mine/4clc) | Crystal structure of Ybr137w protein | Descriptor: | UPF0303 PROTEIN YBR137W | Authors: | Yeh, Y.-H, Lin, T.-W, Lin, C.-Y, Hsiao, C.-D. | Deposit date: | 2014-01-14 | Release date: | 2014-11-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Functional Characterization of Ybr137Wp Implicate its Involvement in the Targeting of Tail-Anchored Proteins to Membranes. Mol.Cell.Biol., 34, 2014
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7TZO
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![BU of 7tzo by Molmil](/molmil-images/mine/7tzo) | The apo structure of human mTORC2 complex | Descriptor: | Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ... | Authors: | Yu, Z, Chen, J, Pearce, D. | Deposit date: | 2022-02-16 | Release date: | 2023-01-11 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. J.Biol.Chem., 298, 2022
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7WB5
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![BU of 7wb5 by Molmil](/molmil-images/mine/7wb5) | local structure of hu33 and spike | Descriptor: | Surface glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hu33 heavy chain, ... | Authors: | Pulan, L. | Deposit date: | 2021-12-15 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants. Signal Transduct Target Ther, 7, 2022
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7WBH
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![BU of 7wbh by Molmil](/molmil-images/mine/7wbh) | overall structure of hu33 and spike | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Pulan, L. | Deposit date: | 2021-12-16 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants. Signal Transduct Target Ther, 7, 2022
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7WL2
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7WL9
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![BU of 7wl9 by Molmil](/molmil-images/mine/7wl9) | Mouse Pendrin in chloride and bicarbonate in asymmetric state | Descriptor: | CHLORIDE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-12 | Release date: | 2023-04-12 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
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7WLE
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7WLA
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7WK1
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![BU of 7wk1 by Molmil](/molmil-images/mine/7wk1) | Mouse Pendrin bound chloride in inward state | Descriptor: | CHLORIDE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-08 | Release date: | 2023-04-12 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
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7WL7
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7WK7
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![BU of 7wk7 by Molmil](/molmil-images/mine/7wk7) | Mouse Pendrin bound bicarbonate in inward state | Descriptor: | BICARBONATE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-08 | Release date: | 2023-05-17 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
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7WLB
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7WL8
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3C27
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![BU of 3c27 by Molmil](/molmil-images/mine/3c27) | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors | Descriptor: | Hirudin-3A, N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide, Thrombin heavy chain, ... | Authors: | Spurlino, J.C, McMillan, M, Lewandowski, F, Milligan, C. | Deposit date: | 2008-01-24 | Release date: | 2009-02-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.182 Å) | Cite: | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors To be Published
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7KM6
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![BU of 7km6 by Molmil](/molmil-images/mine/7km6) | APOBEC3B antibody 5G7 Fv-clasp | Descriptor: | 1,2-ETHANEDIOL, 5G7 human monoclonal FAB heavy chain, 5G7 human monoclonal FAB light chain, ... | Authors: | Tang, H, Shi, K, Aihara, H. | Deposit date: | 2020-11-02 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural Characterization of a Minimal Antibody against Human APOBEC3B. Viruses, 13, 2021
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7KHM
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![BU of 7khm by Molmil](/molmil-images/mine/7khm) | Crystal structure of hDHHS20 bound to palmitoyl CoA | Descriptor: | Isoform 4 of Palmitoyltransferase ZDHHC20, PHOSPHATE ION, Palmitoyl-CoA, ... | Authors: | Lee, C.-J, Banerjee, A. | Deposit date: | 2020-10-21 | Release date: | 2022-02-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase. Proc.Natl.Acad.Sci.USA, 119, 2022
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