8XOO
 
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8XN4
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8Y5W
 | | human NaS1 intermediate state 2 | | Descriptor: | SODIUM ION, SULFATE ION, Solute carrier family 13 member 1 | | Authors: | Zhang, S.S. | | Deposit date: | 2024-02-01 | | Release date: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
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8Y5Z
 | | human NaS1 inward state | | Descriptor: | SODIUM ION, SULFATE ION, Solute carrier family 13 member 1 | | Authors: | Zhang, S.S. | | Deposit date: | 2024-02-01 | | Release date: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
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8Y5Y
 | | human NaS1 outward state | | Descriptor: | SULFATE ION, Solute carrier family 13 member 1 | | Authors: | Zhang, S.S. | | Deposit date: | 2024-02-01 | | Release date: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
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8Y5X
 | | human NaS1 intermediate state 3 | | Descriptor: | SODIUM ION, SULFATE ION, Solute carrier family 13 member 1 | | Authors: | Zhang, S.S. | | Deposit date: | 2024-02-01 | | Release date: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
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7XYD
 | | Crystal structure of TMPRSS2 in complex with Nafamostat | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | | Authors: | Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-12-06 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
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7Y0F
 | | Crystal structure of TMPRSS2 in complex with UK-371804 | | Descriptor: | 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | | Deposit date: | 2022-06-04 | | Release date: | 2023-12-06 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
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7Y0E
 | | Crystal structure of TMPRSS2 in complex with Camostat | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | | Authors: | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | | Deposit date: | 2022-06-04 | | Release date: | 2023-12-06 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
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8Z7M
 | | The crystal structure of AFM-1 | | Descriptor: | Metallo-beta-lactamase type 2, ZINC ION | | Authors: | Xiao, Y.J, Wang, Z.F. | | Deposit date: | 2024-04-20 | | Release date: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insight into the subclass B1 metallo-beta-lactamase AFM-1.
Biochem.Biophys.Res.Commun., 720, 2024
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8XH7
 | | Structure of EBV LMP1 oligomer | | Descriptor: | Latent membrane protein 1 | | Authors: | Gao, P, Huang, J.F. | | Deposit date: | 2023-12-17 | | Release date: | 2024-06-26 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Assembly and activation of EBV latent membrane protein 1.
Cell, 187, 2024
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8XH6
 | | Structure of EBV LMP1 dimer | | Descriptor: | Latent membrane protein 1 | | Authors: | Gao, P, Huang, J.F. | | Deposit date: | 2023-12-17 | | Release date: | 2024-06-26 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Assembly and activation of EBV latent membrane protein 1.
Cell, 187, 2024
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8ZFZ
 | | cryo-EM structure of Gs-coupled zebrafish GPR4 at pH 6.5 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Ma, Y, Tang, M, Ru, H, Song, G. | | Deposit date: | 2024-05-08 | | Release date: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of an activated GPR4-Gs signaling complex.
Nat Commun, 16, 2025
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7VCP
 | | Frischella perrara beta-fructofuranosidase in complex with fructose | | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Sucrose-6-phosphate hydrolase, ... | | Authors: | Tonozuka, T. | | Deposit date: | 2021-09-03 | | Release date: | 2022-03-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Enzymatic and structural characterization of beta-fructofuranosidase from the honeybee gut bacterium Frischella perrara.
Appl.Microbiol.Biotechnol., 106, 2022
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7VCO
 | | Frischella perrara beta-fructofuranosidase | | Descriptor: | DI(HYDROXYETHYL)ETHER, Sucrose-6-phosphate hydrolase, TRIETHYLENE GLYCOL | | Authors: | Tonozuka, T. | | Deposit date: | 2021-09-03 | | Release date: | 2022-03-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Enzymatic and structural characterization of beta-fructofuranosidase from the honeybee gut bacterium Frischella perrara.
Appl.Microbiol.Biotechnol., 106, 2022
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7UN5
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7UMQ
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7V48
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7V47
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7V49
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7CKI
 | | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP | | Descriptor: | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lyu, G, Fan, S, Jin, Y, Liu, J, Zou, S, Wu, G, Yang, Z. | | Deposit date: | 2020-07-17 | | Release date: | 2021-07-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP
To Be Published
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7DRK
 | | Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ... | | Authors: | Yang, B.W, Liu, Z.F. | | Deposit date: | 2020-12-28 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.
Curr Res Struct Biol, 3, 2021
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7DRJ
 | | Crystal structure of phosphatidylglycerol phosphate synthase in complex with phosphatidylglycerol phosphate | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, ACETIC ACID, ... | | Authors: | Yang, B.W, Liu, Z.F. | | Deposit date: | 2020-12-28 | | Release date: | 2021-12-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.
Curr Res Struct Biol, 3, 2021
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7C1D
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7EG4
 | | Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex | | Descriptor: | MAGNESIUM ION, Parvine, Schlafen family member 12, ... | | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | | Deposit date: | 2021-03-24 | | Release date: | 2021-09-29 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells.
Nat Commun, 12, 2021
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