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8FH2
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BU of 8fh2 by Molmil
Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION
Authors:Doamekpor, S.K, Tong, L.
Deposit date:2022-12-13
Release date:2023-04-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
Acta Crystallogr.,Sect.F, 79, 2023
8FGZ
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BU of 8fgz by Molmil
Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y/F877L with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION
Authors:Doamekpor, S.K, Tong, L.
Deposit date:2022-12-13
Release date:2023-04-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
Acta Crystallogr.,Sect.F, 79, 2023
8FGY
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BU of 8fgy by Molmil
Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y/F877L/T878A with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor
Authors:Doamekpor, S.K, Tong, L.
Deposit date:2022-12-13
Release date:2023-04-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
Acta Crystallogr.,Sect.F, 79, 2023
8FH0
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BU of 8fh0 by Molmil
Crystal structure of mutant Androgen Receptor ligand binding domain H875Y/F877L/T878A with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION
Authors:Doamekpor, S.K, Tong, L.
Deposit date:2022-12-13
Release date:2023-04-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
Acta Crystallogr.,Sect.F, 79, 2023
8FH1
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BU of 8fh1 by Molmil
Crystal structure of mutant Androgen Receptor ligand binding domain F877L/T878A with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION
Authors:Doamekpor, S.K, Tong, L.
Deposit date:2022-12-13
Release date:2023-04-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
Acta Crystallogr.,Sect.F, 79, 2023
2I7X
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BU of 2i7x by Molmil
Structure of Yeast CPSF-100 (Ydh1p)
Descriptor: Protein CFT2
Authors:Mandel, C.R, Zhang, H, Gebauer, D, Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
1TO0
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BU of 1to0 by Molmil
X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis
Descriptor: Hypothetical UPF0247 protein yyda
Authors:Kuzin, A.P, Edstrom, W, Vorobiev, S.M, Shastry, R, Ma, L.-C, Xiao, R, Acton, T, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-06-11
Release date:2004-07-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis
To be Published
3K94
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BU of 3k94 by Molmil
Crystal Structure of Thiamin pyrophosphokinase from Geobacillus thermodenitrificans, Northeast Structural Genomics Consortium Target GtR2
Descriptor: Thiamin pyrophosphokinase
Authors:Kuzin, A, Su, M, Seetharaman, J, Janjua, J, Xiao, R, Patel, D.J, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-15
Release date:2010-02-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Northeast Structural Genomics Consortium Target GtR2
To be Published
1TZA
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BU of 1tza by Molmil
X-ray structure of Northeast Structural Genomics Consortium target SoR45
Descriptor: CACODYLATE ION, apaG protein
Authors:Kuzin, A.P, Vorobiev, S.M, Edstrom, W, Acton, T.B, Shastry, R, Ma, L.-C, Cooper, B, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-07-09
Release date:2004-07-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure of Northeast Structural Genomics Consortium target SoR45
To be Published
3KAT
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BU of 3kat by Molmil
Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E
Descriptor: NACHT, LRR and PYD domains-containing protein 1
Authors:Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-19
Release date:2009-10-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Northeast Structural Genomics Consortium Target HR3486E
To be Published
1U1W
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BU of 1u1w by Molmil
Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79
Descriptor: 3-HYDROXYANTHRANILIC ACID, ACETATE ION, GLYCEROL, ...
Authors:Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V.
Deposit date:2004-07-16
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens.
Proc.Natl.Acad.Sci.USA, 101, 2004
2IBO
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BU of 2ibo by Molmil
X-ray Crystal Structure of Protein SP2199 from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR31
Descriptor: Hypothetical protein SP2199
Authors:Seetharaman, J, Abashidze, M, Forouhar, F, Shastry, R, Conover, K, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-09-11
Release date:2006-10-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the hypothetical protein SP2199 from Streptococcus pneumoniae, Northeast structural genomics target SpR31
To be Published
2I2L
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BU of 2i2l by Molmil
X-ray Crystal Structure of Protein yopX from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR411.
Descriptor: YopX protein
Authors:Vorobiev, S.M, Zhou, W, Seetharaman, J, Forouhar, F, Kuzin, A.A, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Acton, T, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-08-16
Release date:2006-08-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the hypothetical protein yopX from Bacillus subtilis
To be Published
1U1X
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BU of 1u1x by Molmil
Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79
Descriptor: (2S,3S)-TRANS-2,3-DIHYDRO-3-HYDROXYANTHRANILIC ACID, Phenazine biosynthesis protein phzF
Authors:Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V.
Deposit date:2004-07-16
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens.
Proc.Natl.Acad.Sci.USA, 101, 2004
1TWD
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BU of 1twd by Molmil
Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
Descriptor: Copper homeostasis protein cutC
Authors:Forouhar, F, Lee, I, Vorobiev, S.M, Ma, L.-C, Shastry, R, Conover, K, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-06-30
Release date:2004-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
To be Published
1TZ9
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BU of 1tz9 by Molmil
Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41
Descriptor: Mannonate dehydratase
Authors:Forouhar, F, Chen, Y, Xiao, R, Cooper, B, Shastry, R, Acton, T.A, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-07-09
Release date:2004-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41
To be Published
2IFT
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BU of 2ift by Molmil
Crystal structure of putative methylase HI0767 from Haemophilus influenzae. NESG target IR102.
Descriptor: Putative methylase HI0767
Authors:Vorobiev, S.M, Su, M, Seetharaman, J, Shastry, R, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-09-21
Release date:2006-10-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the putative methylase HI0767 from Haemophilus influenzae.
To be Published
2IMJ
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BU of 2imj by Molmil
X-ray Crystal Structure of Protein PFL_3262 from Pseudomonas fluorescens. Northeast Structural Genomics Consortium Target PlR14.
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Hypothetical protein DUF1348
Authors:Zhou, W, Forouhar, F, Seetharaman, J, Chen, C.X, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-10-04
Release date:2006-10-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the hypothetical protein (DUF1348) from Pseudomonas fluorescens, Northeast Structural Genomics target PlR14.
TO BE PUBLISHED
2IN5
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BU of 2in5 by Molmil
Crystal Structure of the hypothetical lipoprotein YmcC from Escherichia coli (K12), Northeast Structural Genomics target ER552.
Descriptor: Hypothetical lipoprotein ymcC
Authors:Zhou, W, Forouhar, F, Seetharaman, J, Chen, C.X, Cunningham, K, Ma, L.-C, Janjua, H, Xiao, R, Baran, M.C, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-10-05
Release date:2006-11-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the hypothetical lipoprotein YmcC from Escherichia coli (K12), Northeast Structural Genomics target ER552.
TO BE PUBLISHED
1U1V
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BU of 1u1v by Molmil
Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79
Descriptor: GLYCEROL, Phenazine biosynthesis protein phzF, SULFATE ION
Authors:Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V.
Deposit date:2004-07-16
Release date:2004-11-02
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens.
Proc.Natl.Acad.Sci.USA, 101, 2004
3D5N
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BU of 3d5n by Molmil
Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125.
Descriptor: Q97W15_SULSO
Authors:Vorobiev, S.M, Chen, Y, Seetharaman, J, Lee, D, Foote, R.E, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-05-16
Release date:2008-07-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125.
To be Published
3CGW
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BU of 3cgw by Molmil
Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei. Northeast Structural Genomics Consortium target MaR46
Descriptor: LPPG:FO 2-phospho-L-lactate transferase
Authors:Forouhar, F, Abashidze, M, Seetharaman, J, Vorobiev, S.M, Ciao, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-03-06
Release date:2008-03-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular insights into the biosynthesis of the f420 coenzyme.
J.Biol.Chem., 283, 2008
5DTJ
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BU of 5dtj by Molmil
Crystal Structure of dfp-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134
Descriptor: 1-[5-(2,4-dichlorophenoxy)pentyl]-1H-imidazole, Acetylcholinesterase
Authors:Tran, T.H, Tong, L.
Deposit date:2015-09-18
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Chembiochem, 16, 2015
8T1R
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BU of 8t1r by Molmil
Crystal structure of human CPSF73 catalytic segment in complex with compound 2
Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(3-methoxyphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ...
Authors:Huang, J, Tong, L.
Deposit date:2023-06-02
Release date:2023-11-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Cell Chem Biol, 31, 2024
8T1Q
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BU of 8t1q by Molmil
Crystal structure of human CPSF73 catalytic segment in complex with compound 1
Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ...
Authors:Huang, J, Tong, L.
Deposit date:2023-06-02
Release date:2023-11-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Cell Chem Biol, 31, 2024

238582

数据于2025-07-09公开中

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