8FGY

Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y/F877L/T878A with DHT

Summary for 8FGY

Entry DOI	10.2210/pdb8fgy/pdb
Descriptor	Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE (3 entities in total)
Functional Keywords	ar, androgen receptor, dht, steroid receptor, gene regulation
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	30370.58
Authors	Doamekpor, S.K.,Tong, L. (deposition date: 2022-12-13, release date: 2023-04-12)
Primary citation	Doamekpor, S.K.,Peng, P.,Xu, R.,Ma, L.,Tong, Y.,Tong, L. A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations. Acta Crystallogr.,Sect.F, 79:95-104, 2023 Cited by PubMed: 36995121 DOI: 10.1107/S2053230X23002224 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation