7D6Y
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![BU of 7d6y by Molmil](/molmil-images/mine/7d6y) | eIF4E in Complex with a Disulphide-Free Autonomous VH Domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Eukaryotic translation initiation factor 4E, VH Domain (1C5), ... | Authors: | Brown, C.J, Frosi, Y, Jiang, S, Lin, Y.C. | Deposit date: | 2020-10-02 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.668 Å) | Cite: | Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways To Be Published
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5MH3
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5MH1
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![BU of 5mh1 by Molmil](/molmil-images/mine/5mh1) | Crystal structure of a DM9 domain containing protein from Crassostrea gigas | Descriptor: | GLYCEROL, MAGNESIUM ION, Natterin-3, ... | Authors: | Weinert, T, Warkentin, E, Pang, G. | Deposit date: | 2016-11-22 | Release date: | 2017-12-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum. Front Immunol, 8, 2017
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4JAC
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![BU of 4jac by Molmil](/molmil-images/mine/4jac) | Dehaloperoxidase-Hemoglobin T56S | Descriptor: | AZIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Franzen, S, Swartz, P.D. | Deposit date: | 2013-02-18 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.934 Å) | Cite: | The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata. Biochim.Biophys.Acta, 1834, 2013
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5MH2
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![BU of 5mh2 by Molmil](/molmil-images/mine/5mh2) | |
5MH0
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![BU of 5mh0 by Molmil](/molmil-images/mine/5mh0) | |
6KZU
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![BU of 6kzu by Molmil](/molmil-images/mine/6kzu) | |
6KYA
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![BU of 6kya by Molmil](/molmil-images/mine/6kya) | Crystal structure of human TLR8 in complex TH1027 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,4-triazol-3-yl]propan-1-ol, ... | Authors: | Tanji, H, Sakaniwa, K, Ohto, U, Shimizu, T. | Deposit date: | 2019-09-17 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein Interface. J.Med.Chem., 63, 2020
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8H9D
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![BU of 8h9d by Molmil](/molmil-images/mine/8h9d) | Crystal structure of Cas12a protein | Descriptor: | Cas12A, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3'), ... | Authors: | Jianwei, L, Jobichen, C, Sivaraman, J. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21, 2023
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8I54
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![BU of 8i54 by Molmil](/molmil-images/mine/8i54) | Lb2Cas12a RNA DNA complex | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*TP*GP*CP*TP*TP*TP*A)-3'), Lb2Cas12a, ... | Authors: | Li, J, Sivaraman, J, Satoru, M. | Deposit date: | 2023-01-24 | Release date: | 2023-02-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21, 2023
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7C29
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![BU of 7c29 by Molmil](/molmil-images/mine/7c29) | Esterase CrmE10 mutant-D178A | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Li, Z, Li, J. | Deposit date: | 2020-05-07 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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7C82
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![BU of 7c82 by Molmil](/molmil-images/mine/7c82) | Crystal structure of AlinE4, a SGNH-hydrolase family esterase | Descriptor: | ACETATE ION, ALANINE, CADMIUM ION, ... | Authors: | Li, Z, Li, J. | Deposit date: | 2020-05-28 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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7C84
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![BU of 7c84 by Molmil](/molmil-images/mine/7c84) | Esterase AlinE4 mutant, D162A | Descriptor: | ACETATE ION, CADMIUM ION, GLYCEROL, ... | Authors: | Li, Z, Li, J. | Deposit date: | 2020-05-28 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.552 Å) | Cite: | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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7C85
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![BU of 7c85 by Molmil](/molmil-images/mine/7c85) | Esterase AlinE4 mutant-S13A | Descriptor: | ACETATE ION, CADMIUM ION, SGNH-hydrolase family esterase | Authors: | Li, Z, Li, J. | Deposit date: | 2020-05-28 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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7C23
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![BU of 7c23 by Molmil](/molmil-images/mine/7c23) | Crystal structure of CrmE10, a SGNH-hydrolase family esterase | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Li, Z, Li, J. | Deposit date: | 2020-05-07 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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5ZLU
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![BU of 5zlu by Molmil](/molmil-images/mine/5zlu) | Ribosome Structure bound to ABC-F protein. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Su, W.X, Kumar, V, Ero, R, Andrew, S.W.W, Jian, S, Yong-Gui, G. | Deposit date: | 2018-03-29 | Release date: | 2018-08-01 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ribosome protection by antibiotic resistance ATP-binding cassette protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1QR9
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![BU of 1qr9 by Molmil](/molmil-images/mine/1qr9) | INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION | Descriptor: | GP41 ENVELOPE PROTEIN | Authors: | Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M. | Deposit date: | 1999-06-18 | Release date: | 1999-11-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion. J.Virol., 73, 1999
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1QR8
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![BU of 1qr8 by Molmil](/molmil-images/mine/1qr8) | INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION | Descriptor: | GP41 ENVELOPE PROTEIN | Authors: | Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M. | Deposit date: | 1999-06-18 | Release date: | 1999-11-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion. J.Virol., 73, 1999
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5J9U
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![BU of 5j9u by Molmil](/molmil-images/mine/5j9u) | Crystal structure of the NuA4 core complex | Descriptor: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | Authors: | Chen, Z.C, Xu, P. | Deposit date: | 2016-04-11 | Release date: | 2016-10-26 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism Mol.Cell, 63, 2016
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5XR8
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![BU of 5xr8 by Molmil](/molmil-images/mine/5xr8) | Crystal structure of the human CB1 in complex with agonist AM841 | Descriptor: | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, CHOLESTEROL, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | Authors: | Hua, T, Vemuri, K, Nikas, P.S, Laprairie, R.B, Wu, Y, Qu, L, Pu, M, Korde, A, Shan, J, Ho, J.H, Han, G.W, Ding, K, Li, X, Liu, H, Hanson, M.A, Zhao, S, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | Deposit date: | 2017-06-07 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature, 547, 2017
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5XNV
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![BU of 5xnv by Molmil](/molmil-images/mine/5xnv) | Crystal structure of YEATS2 YEATS bound to H3K27ac peptide | Descriptor: | ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... | Authors: | Li, H.T, Guan, H.P, Zhao, D. | Deposit date: | 2017-05-24 | Release date: | 2017-11-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nat Commun, 8, 2017
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8GU0
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![BU of 8gu0 by Molmil](/molmil-images/mine/8gu0) | Crystal structure of a fungal halogenase RadH | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Non-heme halogenase radH, ... | Authors: | Jiang, S.M, Brown, C.J. | Deposit date: | 2022-09-09 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Further Characterization of Fungal Halogenase RadH and Its Homologs. Biomolecules, 13, 2023
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6RCI
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![BU of 6rci by Molmil](/molmil-images/mine/6rci) | Crystal structure of REXO2 | Descriptor: | Oligoribonuclease, mitochondrial | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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6RCN
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![BU of 6rcn by Molmil](/molmil-images/mine/6rcn) | Crystal structure of REXO2-D199A-dAdA | Descriptor: | DNA (5'-D(P*AP*A)-3'), MAGNESIUM ION, Oligoribonuclease, ... | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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6RCL
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![BU of 6rcl by Molmil](/molmil-images/mine/6rcl) | Crystal structure of REXO2-D199A-AA | Descriptor: | MAGNESIUM ION, Oligoribonuclease, mitochondrial, ... | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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