7D6Y

eIF4E in Complex with a Disulphide-Free Autonomous VH Domain

Summary for 7D6Y

• Entry DOI: 10.2210/pdb7d6y/pdb
• Descriptor: Eukaryotic translation initiation factor 4E, VH Domain (1C5), [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE, ... (5 entities in total)
• Functional Keywords: vh domain, cap-dependent translation, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43017.48

Authors

Brown, C.J.,Frosi, Y.,Jiang, S.,Lin, Y.C. (deposition date: 2020-10-02, release date: 2021-10-06, Last modification date: 2023-11-29)

• Primary citation: Frosi, Y.,Lin, Y.C.,Jiang, S.,Ramlan, S.R.,Hew, K.,Asial, I.,Engman, A.H.,Goh, M.,Thean, D.,Nordlund, P.,Lane, D.P.,Brown, C.J.; Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.668 Å)