7D6Y
eIF4E in Complex with a Disulphide-Free Autonomous VH Domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Eukaryotic translation initiation factor 4E | polymer | 217 | 25130.2 | 1 | UniProt (P06730) Pfam (PF01652) | Homo sapiens (Human) | eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein |
2 | B (B) | VH Domain (1C5) | polymer | 161 | 17154.8 | 1 | Homo sapiens | ||
3 | C (A) | [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE | non-polymer | 537.2 | 1 | Chemie (MGO) | |||
4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
5 | E, F (A, B) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42285.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 732.5 | |
All* | Total formula weight | 43017.5 |