2JM1
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2XCZ
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![BU of 2xcz by Molmil](/molmil-images/mine/2xcz) | Crystal Structure of macrophage migration inhibitory factor homologue from Prochlorococcus marinus | Descriptor: | DI(HYDROXYETHYL)ETHER, POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN | Authors: | Wasiel, A.A, Rozeboom, H.J, Hauke, D, Baas, B.J, Zandvoort, E, Quax, W.J, Thunnissen, A.M.W.H, Poelarends, G.J. | Deposit date: | 2010-04-27 | Release date: | 2010-09-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus Marinus. Biochemistry, 49, 2010
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2XHE
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![BU of 2xhe by Molmil](/molmil-images/mine/2xhe) | Crystal structure of the Unc18-syntaxin 1 complex from Monosiga brevicollis | Descriptor: | SYNTAXIN1, UNC18 | Authors: | Burkhardt, P, Stegmann, C.M, Wahl, M.C, Fasshauer, D. | Deposit date: | 2010-06-14 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Primordial Neurosecretory Apparatus Identified in the Choanoflagellate Monosiga Brevicollis. Proc.Natl.Acad.Sci.USA, 108, 2011
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5A3O
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![BU of 5a3o by Molmil](/molmil-images/mine/5a3o) | Crystal structure of the LecB lectin from Pseudomonas aeruginosa in complex with Methyl 6-(cinnamido)-6-deoxy-alpha-D-mannopyranoside at 1.6 ansgtrom | Descriptor: | CALCIUM ION, CHLORIDE ION, CINNAMIDE, ... | Authors: | Sommer, R, Hauck, D, Varrot, A, Audfray, A, Imberty, A, Titz, A. | Deposit date: | 2015-06-02 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cinnamide Derivatives of D-Mannose as Inhibitors of the Bacterial Virulence Factor Lecb from Pseudomonas Aeruginosa Chemistryopen, 4, 2015
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2BN6
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![BU of 2bn6 by Molmil](/molmil-images/mine/2bn6) | P-Element Somatic Inhibitor Protein | Descriptor: | PSI | Authors: | Ignjatovic, T, Yang, J.C, Butler, P.J.G, Neuhaus, D, Nagai, K. | Deposit date: | 2005-03-21 | Release date: | 2005-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase. J.Mol.Biol., 351, 2005
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2BN5
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![BU of 2bn5 by Molmil](/molmil-images/mine/2bn5) | P-Element Somatic Inhibitor Protein Complex with U1-70k proline-rich peptide | Descriptor: | PSI, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA | Authors: | Ignjatovic, T, Yang, J.-C, Butler, P.J.G, Neuhaus, D, Nagai, K. | Deposit date: | 2005-03-21 | Release date: | 2005-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase. J.Mol.Biol., 351, 2005
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2BO5
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![BU of 2bo5 by Molmil](/molmil-images/mine/2bo5) | Bovine oligomycin sensitivity conferral protein N-terminal domain | Descriptor: | ATP SYNTHASE OLIGOMYCIN SENSITIVITY CONFERRAL PROTEIN | Authors: | Carbajo, R.J, Kellas, F.A, Runswick, M.J, Montgomery, M.G, Walker, J.E, Neuhaus, D. | Deposit date: | 2005-04-07 | Release date: | 2005-08-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the F1-binding domain of the stator of bovine F1Fo-ATPase and how it binds an alpha-subunit. J. Mol. Biol., 351, 2005
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1HF9
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![BU of 1hf9 by Molmil](/molmil-images/mine/1hf9) | C-Terminal Coiled-Coil Domain from Bovine IF1 | Descriptor: | ATPASE INHIBITOR (MITOCHONDRIAL) | Authors: | Gordon-Smith, D.J, Carbajo, R.J, Yang, J.-C, Videler, H, Runswick, M.J, Walker, J.E, Neuhaus, D. | Deposit date: | 2000-11-30 | Release date: | 2001-05-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase. J. Mol. Biol., 308, 2001
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1GO5
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1FHT
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![BU of 1fht by Molmil](/molmil-images/mine/1fht) | RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | Deposit date: | 1996-02-21 | Release date: | 1996-07-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding. J.Mol.Biol., 257, 1996
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1HMA
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![BU of 1hma by Molmil](/molmil-images/mine/1hma) | THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER | Descriptor: | HMG-D | Authors: | Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D. | Deposit date: | 1994-05-12 | Release date: | 1994-07-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster. Structure, 2, 1994
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1DZ5
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![BU of 1dz5 by Molmil](/molmil-images/mine/1dz5) | The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | Descriptor: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | Authors: | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | Deposit date: | 2000-02-16 | Release date: | 2000-03-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein Nat.Struct.Biol., 7, 2000
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2N1T
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![BU of 2n1t by Molmil](/molmil-images/mine/2n1t) | Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution | Descriptor: | Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ... | Authors: | Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J. | Deposit date: | 2015-04-21 | Release date: | 2015-06-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nat.Struct.Mol.Biol., 22, 2015
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6TL0
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![BU of 6tl0 by Molmil](/molmil-images/mine/6tl0) | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of VPS29 with VARP 687-747 | Descriptor: | Ankyrin repeat domain-containing protein 27, Vacuolar protein sorting-associated protein 29, ZINC ION | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Crawley-Snowdon, H. | Deposit date: | 2019-11-29 | Release date: | 2020-10-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nat Commun, 11, 2020
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8AUT
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![BU of 8aut by Molmil](/molmil-images/mine/8aut) | WelO5* L221A bound to Zn(II), Cl, 2-oxoglutarate, and 12-epi-hapalindole C | Descriptor: | 2-OXOGLUTARIC ACID, 3-[(1~{S},2~{R},3~{S},6~{S})-3-ethenyl-2-isocyano-3-methyl-6-prop-1-en-2-yl-cyclohexyl]-1~{H}-indole, CHLORIDE ION, ... | Authors: | Buller, R, Hueppi, S, Voss, M, Schaub, D. | Deposit date: | 2022-08-25 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.685 Å) | Cite: | Enzyme engineering enables inversion of substrate stereopreference of the halogenase WelO5* Chemcatchem, 2022
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6GYI
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3HGJ
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![BU of 3hgj by Molmil](/molmil-images/mine/3hgj) | Old Yellow Enzyme from Thermus scotoductus SA-01 complexed with p-hydroxy-benzaldehyde | Descriptor: | Chromate reductase, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZALDEHYDE | Authors: | Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E. | Deposit date: | 2009-05-14 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01 Biochem.Biophys.Res.Commun., 393, 2010
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6RH5
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![BU of 6rh5 by Molmil](/molmil-images/mine/6rh5) | Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain | Descriptor: | Adaptin ear-binding coat-associated protein 1 | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | Deposit date: | 2019-04-18 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6S53
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![BU of 6s53 by Molmil](/molmil-images/mine/6s53) | Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | Authors: | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | Deposit date: | 2019-06-30 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nat Commun, 10, 2019
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7AAA
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![BU of 7aaa by Molmil](/molmil-images/mine/7aaa) | Crystal structure of the catalytic domain of human PARP1 (apo) | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Underwood, E, Rawlins, P.B, Johannes, J.W, Easton, L.E, Embrey, K.J, Neuhaus, D. | Deposit date: | 2020-09-04 | Release date: | 2021-01-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
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7AAB
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![BU of 7aab by Molmil](/molmil-images/mine/7aab) | Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47 | Descriptor: | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | Deposit date: | 2020-09-04 | Release date: | 2021-01-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
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7AAD
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![BU of 7aad by Molmil](/molmil-images/mine/7aad) | Crystal structure of the catalytic domain of human PARP1 in complex with olaparib | Descriptor: | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 1, SULFATE ION | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | Deposit date: | 2020-09-04 | Release date: | 2021-01-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
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7AAC
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![BU of 7aac by Molmil](/molmil-images/mine/7aac) | Crystal structure of the catalytic domain of human PARP1 in complex with veliparib | Descriptor: | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1, SULFATE ION | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | Deposit date: | 2020-09-04 | Release date: | 2021-01-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.593 Å) | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
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6RH6
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![BU of 6rh6 by Molmil](/molmil-images/mine/6rh6) | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163 | Descriptor: | AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1 | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | Deposit date: | 2019-04-18 | Release date: | 2019-09-04 | Method: | SOLUTION NMR | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6IAV
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![BU of 6iav by Molmil](/molmil-images/mine/6iav) | |