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6UGU
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BU of 6ugu by Molmil
Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a C-centered orthorhombic crystal form, Lot C
Descriptor: PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain
Authors:Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGS
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BU of 6ugs by Molmil
Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A
Descriptor: Infliximab (Remicade) Fab Heavy Chain, Infliximab (Remicade) Fab Light Chain
Authors:Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGX
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BU of 6ugx by Molmil
Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a primative orthorhombic crystal form, Lot A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mayclin, S.J, Edwards, T.E.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
5K85
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BU of 5k85 by Molmil
Crystal Structure of Acetyl-CoA Synthetase in Complex with Adenosine-5'-propylphosphate and Coenzyme A from Cryptococcus neoformans H99
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-MONOPHOSPHATE-PROPYL ESTER, Acetyl-coenzyme A synthetase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D, Delker, S.L, Potts, K.T, Lorimer, D.D, Edwards, T.E, Mutz, M.W, SSGCID
Deposit date:2016-05-27
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CRYSTAL STRUCTURE OF ACETYL-COA SYNTHETASE IN COMPLEX WITH ADENOSINE-5'-PROPYLPHOSPHATE AND COENZYME A FROM CRYPTOCOCCUS NEOFORMANS H99
To Be Published
5K8F
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BU of 5k8f by Molmil
Crystal structure of Acetyl-CoA Synthetase in complex with ATP and Acetyl-AMP from Cryptococcus neoformans H99
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Acetyl-coenzyme A synthetase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D, Delker, S.L, Potts, K.T, Lorimer, D.D, Edwards, T.E, Mutz, M.W.
Deposit date:2016-05-30
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Acetyl-CoA Synthetase in complex with ATP and Acetyl-AMP from Cryptococcus neoformans H99
To Be Published
5KLX
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BU of 5klx by Molmil
Crystal Structure of SMT Fusion Peptidyl-Prolyl Cis-Trans Isomerase from Burkholderia Pseudomallei Complexed with SF110
Descriptor: 2-[(2~{S})-1-(phenylmethyl)sulfonylpiperidin-2-yl]carbonyloxyethyl pyridine-3-carboxylate, Chimera protein of Ubiquitin-like protein SMT3 and Peptidyl-prolyl cis-trans isomerase, DI(HYDROXYETHYL)ETHER, ...
Authors:Fox III, D, Edwards, T.E.
Deposit date:2016-06-26
Release date:2017-05-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of SMT Fusion Peptidyl-Prolyl Cis-Trans Isomerase from Burkholderia Pseudomallei Complexed with SF110
To Be Published
4WHX
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BU of 4whx by Molmil
X-ray Crystal Structure of an Amino Acid Aminotransferase from Burkholderia pseudomallei Bound to the Co-factor Pyridoxal Phosphate
Descriptor: 1,2-ETHANEDIOL, ALANINE, Branched-chain-amino-acid transaminase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fairman, J.W, Dranow, D.M, Taylor, B.M, Lorimer, D, Edwards, T.E.
Deposit date:2014-09-23
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray Crystal Structure of an Amino Acid Aminotransferase from Burkholderia pseudomallei Bound to the Co-factor Pyridoxal Phosphate
to be published
4WJB
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BU of 4wjb by Molmil
X-ray crystal structure of a putative amidohydrolase/peptidase from Burkholderia cenocepacia
Descriptor: 1,2-ETHANEDIOL, Putative amidohydrolase/peptidase, SULFATE ION, ...
Authors:Lukacs, C.M, Dranow, D.M, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-09-29
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:X-ray crystal structure of a putative amidohydrolase/peptidase from Burkholderia cenocepacia
To Be Published
4YET
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BU of 4yet by Molmil
X-ray crystal structure of superoxide dismutase from Babesia bovis solved by Sulfur SAD
Descriptor: FE (III) ION, Superoxide dismutase
Authors:Fairman, J.W, Clifton, M.C, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-02-24
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Acta Crystallogr.,Sect.F, 71, 2015
4ZBN
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BU of 4zbn by Molmil
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-nerve growth factor, DNA (28-MER)
Authors:Davies, D.R, Edwards, T.E.
Deposit date:2015-04-15
Release date:2015-06-10
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Structure, 23, 2015
8DGD
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BU of 8dgd by Molmil
Crystal Structure of GAF domain-containing protein, from Klebsiella pneumoniae
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GAF domain-containing protein, ZINC ION
Authors:Seattle Structural Genomics Center for Infectious Disease, Delker, S.L, Weiss, M.J, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-06-23
Release date:2023-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of GAF domain-containing protein, from Klebsiella pneumoniae
to be published
4G7F
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BU of 4g7f by Molmil
Crystal Structure of Enolase from Trypanosoma Cruzi
Descriptor: 1,2-ETHANEDIOL, Enolase, MAGNESIUM ION
Authors:Craig, T.K, Edwards, T.E, Staker, B, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-07-20
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Enolase from Trypanosoma Cruzi
To be Published
4H4G
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BU of 4h4g by Molmil
Crystal Structure of (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase from Burkholderia thailandensis E264
Descriptor: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Authors:Craig, T.K, Edwards, T.E, Staker, B, Stewart, L, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-09-17
Release date:2012-10-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4HQX
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BU of 4hqx by Molmil
CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A Modified nucleotide aptamer (SOMAmer SL4)
Descriptor: MAGNESIUM ION, Platelet-derived growth factor subunit B, SODIUM ION, ...
Authors:Davies, D.R, Edwards, T.E, Janjic, N, Gelinas, A.D, Zhang, C, Jarvis, T.C.
Deposit date:2012-10-26
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HQU
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BU of 4hqu by Molmil
Crystal structure of human PDGF-BB in complex with a modified nucleotide aptamer (SOMAmer SL5)
Descriptor: MAGNESIUM ION, Platelet-derived growth factor subunit B, SODIUM ION, ...
Authors:Davies, D.R, Edwards, T.E, Janjic, N, Gelinas, A.D, Zhang, C, Jarvis, T.C.
Deposit date:2012-10-26
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
4KMS
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BU of 4kms by Molmil
Crystal structure of Acetoacetyl-CoA reductase from Rickettsia felis
Descriptor: Acetoacetyl-CoA reductase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J, Lukacs, C, Edwards, T.E, Lorimer, D.
Deposit date:2013-05-08
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis.
Acta Crystallogr.,Sect.F, 77, 2021
6UGY
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BU of 6ugy by Molmil
Crystal structure of the Fc fragment of anti-TNFa antibody infliximab (Remicade) in a primative orthorhombic crystal form, Lot C
Descriptor: ACETATE ION, Remicade Fc, ZINC ION, ...
Authors:Mayclin, S.J, Edwards, T.E.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGT
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BU of 6ugt by Molmil
Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a I-centered orthorhombic crystal form, Lot A
Descriptor: 1,2-ETHANEDIOL, PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain
Authors:Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGV
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BU of 6ugv by Molmil
Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C
Descriptor: 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ...
Authors:Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGW
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BU of 6ugw by Molmil
Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A
Descriptor: ACETATE ION, PF-06438179/GP1111 Fc, ZINC ION, ...
Authors:Mayclin, S.J, Edwards, T.E.
Deposit date:2019-09-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
5IFI
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BU of 5ifi by Molmil
CRYSTAL STRUCTURE OF ACETYL-COA SYNTHETASE IN COMPLEX WITH ADENOSINE-5'-PROPYLPHOSPHATE FROM CRYPTOCOCCUS NEOFORMANS H99
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-MONOPHOSPHATE-PROPYL ESTER, Acetyl-coenzyme A synthetase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), SSGCID, Fox III, D, Edwards, T.E, Lorimer, D.D, Mutz, M.W.
Deposit date:2016-02-26
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Acetyl-CoA Synthetase in complex with Adenosine-5'-propylphosphate from Cryptococcus neoformans H99
To Be Published
5DLC
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BU of 5dlc by Molmil
X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa
Descriptor: PHOSPHATE ION, Pyridoxine 5'-phosphate synthase
Authors:Fairman, J.W, Abendroth, J, Lorimer, D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-09-04
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa
To Be Published
3EGZ
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BU of 3egz by Molmil
Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
Descriptor: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ...
Authors:Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2008-09-11
Release date:2008-10-28
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch
Chem.Biol., 15, 2008
3FU2
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BU of 3fu2 by Molmil
Cocrystal structure of a class-I preQ1 riboswitch
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, CALCIUM ION, PreQ1 riboswitch
Authors:Klein, D.J, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2009-01-13
Release date:2009-03-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase
Nat.Struct.Mol.Biol., 16, 2009
4DGQ
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BU of 4dgq by Molmil
Crystal structure of Non-heme chloroperoxidase from Burkholderia cenocepacia
Descriptor: 1,2-ETHANEDIOL, Non-heme chloroperoxidase
Authors:Gardberg, A.S, Edwards, T.E, Abendroth, J.A, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-01-26
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Non-heme chloroperoxidase from Burkholderia cenocepacia
To be Published

221051

数据于2024-06-12公开中

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