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6UKE
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BU of 6uke by Molmil
HhaI endonuclease in Complex with Iodine-Labelled DNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6TKZ
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BU of 6tkz by Molmil
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL, ...
Authors:Barford, D.
Deposit date:2019-11-29
Release date:2020-01-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
6UKA
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BU of 6uka by Molmil
Crystal structure of RHOG and ELMO complex
Descriptor: Engulfment and cell motility protein 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Jo, C.H, Killoran, R.C, Smith, M.J.
Deposit date:2019-10-04
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
6UKH
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BU of 6ukh by Molmil
HhaI endonuclease in Complex with DNA in space group P41212 (pH 6.0)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*G)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6D02
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BU of 6d02 by Molmil
Cross-alpha Amyloid-like Structure alphaAmL, 2nd form
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CARBONATE ION, PHOSPHATE ION, ...
Authors:Zhang, S.-Q, Liu, L, Degrado, W.F.
Deposit date:2018-04-10
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
6DDI
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BU of 6ddi by Molmil
Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue
Descriptor: 1,2-ETHANEDIOL, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, Bromodomain-containing protein 2, ...
Authors:White, S.W, Yun, M.
Deposit date:2018-05-10
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer.
Cancer Res., 80, 2020
6TNT
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BU of 6tnt by Molmil
SUMOylated apoAPC/C with repositioned APC2 WHB domain
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Barford, D, Yatskevich, S.
Deposit date:2019-12-10
Release date:2021-01-13
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
7JM5
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BU of 7jm5 by Molmil
Crystal structure of KDM4B in complex with QC6352
Descriptor: 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4B, NICKEL (II) ION, ...
Authors:White, S.W, Yun, M.
Deposit date:2020-07-31
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.
Sci Transl Med, 14, 2022
5Z9R
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BU of 5z9r by Molmil
NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
Descriptor: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
Authors:Dou, S, Ma, X, Li, D, Liu, C.
Deposit date:2018-02-05
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau.
Elife, 9, 2020
8H2H
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BU of 8h2h by Molmil
Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase
Descriptor: Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3')
Authors:Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2022-10-06
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Functionalized graphene grids with various charges for single-particle cryo-EM.
Nat Commun, 13, 2022
8WKS
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BU of 8wks by Molmil
Cryo-EM structure of DSR2-TUBE complex
Descriptor: SIR2-like domain-containing protein, TUBE
Authors:Gao, A, Huang, J, Zhu, K.
Deposit date:2023-09-28
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
8WKX
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BU of 8wkx by Molmil
Cryo-EM structure of DSR2
Descriptor: SIR2-like domain-containing protein
Authors:Gao, A, Huang, J, Zhu, K.
Deposit date:2023-09-28
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
8WKT
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BU of 8wkt by Molmil
Cryo-EM structure of DSR2-DSAD1 complex
Descriptor: SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI
Authors:Gao, A, Huang, J, Zhu, K.
Deposit date:2023-09-28
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
3BYY
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BU of 3byy by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Descriptor: Enterotoxin type C-3, SULFATE ION, T cell receptor beta chain 8.2
Authors:Cho, S, Eric, J.S.
Deposit date:2008-01-16
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
3BZD
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BU of 3bzd by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Descriptor: Enterotoxin type C-3, SULFATE ION, T cell receptor beta chain 8.2
Authors:Cho, S.
Deposit date:2008-01-17
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
3CB8
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BU of 3cb8 by Molmil
4Fe-4S-Pyruvate formate-lyase activating enzyme in complex with AdoMet and a peptide substrate
Descriptor: FORMIC ACID, IRON/SULFUR CLUSTER, Pyruvate formate-lyase 1-activating enzyme, ...
Authors:Vey, J.L, Drennan, C.L.
Deposit date:2008-02-21
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BYT
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BU of 3byt by Molmil
A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2
Descriptor: Enterotoxin type C-3, T cell receptor beta chain 8.2
Authors:Cho, S, Eric, J.S.
Deposit date:2008-01-16
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
7F2B
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BU of 7f2b by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal RNA binding domain at 2.0A resolution
Descriptor: CHLORIDE ION, Nucleoprotein, PHOSPHATE ION
Authors:Liu, C, Chen, Y.W.
Deposit date:2021-06-10
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the SARS-CoV-2 nucleocapsid protein C-terminal domain and development of nucleocapsid-targeting nanobodies.
Febs J., 289, 2022
3BVM
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BU of 3bvm by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Descriptor: Enterotoxin type C-3, ZINC ION
Authors:Cho, S.
Deposit date:2008-01-07
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
3BVZ
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BU of 3bvz by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Descriptor: Enterotoxin type C-3, ZINC ION
Authors:Cho, S.
Deposit date:2008-01-07
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
7F2E
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BU of 7f2e by Molmil
SARS-CoV-2 nucleocapsid protein C-terminal domain (dodecamer)
Descriptor: Nucleoprotein, PHOSPHATE ION
Authors:Liu, C, Jiang, H.
Deposit date:2021-06-10
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of the SARS-CoV-2 nucleocapsid protein C-terminal domain and development of nucleocapsid-targeting nanobodies.
Febs J., 289, 2022
3BVG
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BU of 3bvg by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Descriptor: Enterotoxin type C-3, ZINC ION
Authors:Cho, S, Eric, J.S.
Deposit date:2008-01-07
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Assessing energetic contributions to binding from a disordered region in a protein-protein interaction
Biochemistry, 49, 2010
3C8F
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BU of 3c8f by Molmil
4Fe-4S-Pyruvate formate-lyase Activating Enzyme with partially disordered AdoMet
Descriptor: IRON/SULFUR CLUSTER, Pyruvate formate-lyase 1-activating enzyme, TRIETHYLENE GLYCOL, ...
Authors:Vey, J.L, Drennan, C.L.
Deposit date:2008-02-11
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ZI0
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BU of 2zi0 by Molmil
Crystal structure of Tav2b/siRNA complex
Descriptor: Protein 2b, RNA (5'-D(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3')
Authors:Yuan, Y.A, Chen, H.-Y.
Deposit date:2008-02-12
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis for RNA-silencing suppression by Tomato aspermy virus protein 2b
Embo Rep., 9, 2008
5Z34
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BU of 5z34 by Molmil
The structure of a chitin deacetylase from Bombyx mori provide the first insight into insect chitin deacetylation mechanism
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin deacetylase, ZINC ION
Authors:Liu, L, Zhou, Y, Yang, Q.
Deposit date:2018-01-05
Release date:2019-02-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:The structure of a chitin deacetylase from Bombyx mori provide the first insight into insect chitin deacetylation mechanism
To Be Published

225399

数据于2024-09-25公开中

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