7MYO
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![BU of 7myo by Molmil](/molmil-images/mine/7myo) | Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719 | Descriptor: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | Deposit date: | 2021-05-21 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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3JCS
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![BU of 3jcs by Molmil](/molmil-images/mine/3jcs) | 2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania | Descriptor: | 26S alpha ribosomal RNA, 26S delta ribosomal RNA, 26S epsilon ribosomal RNA, ... | Authors: | Shalev-Benami, M, Zhang, Y, Matzov, D, Halfon, Y, Zackay, A, Rozenberg, H, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. | Deposit date: | 2016-01-21 | Release date: | 2016-07-20 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania. Cell Rep, 16, 2016
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3JA8
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![BU of 3ja8 by Molmil](/molmil-images/mine/3ja8) | Cryo-EM structure of the MCM2-7 double hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ... | Authors: | Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N. | Deposit date: | 2015-05-09 | Release date: | 2015-08-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the eukaryotic MCM complex at 3.8 angstrom Nature, 524, 2015
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2LD7
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![BU of 2ld7 by Molmil](/molmil-images/mine/2ld7) | Solution structure of the mSin3A PAH3-SAP30 SID complex | Descriptor: | Histone deacetylase complex subunit SAP30, Paired amphipathic helix protein Sin3a | Authors: | Xie, T, He, Y, Korkeamaki, H, Zhang, Y, Imhoff, R, Lohi, O, Radhakrishnan, I. | Deposit date: | 2011-05-16 | Release date: | 2011-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the 30-kDa Sin3-associated protein (SAP30) in complex with the mammalian Sin3A corepressor and its role in nucleic acid binding. J.Biol.Chem., 286, 2011
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3JSF
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3JSG
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3JTU
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8H02
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4HX1
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![BU of 4hx1 by Molmil](/molmil-images/mine/4hx1) | Structure of HLA-A68 complexed with a tumor antigen derived peptide | Descriptor: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2012-11-09 | Release date: | 2013-10-02 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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4I48
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![BU of 4i48 by Molmil](/molmil-images/mine/4i48) | Structure of HLA-A68 complexed with an HIV Env derived peptide | Descriptor: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2012-11-27 | Release date: | 2013-10-02 | Method: | X-RAY DIFFRACTION (2.799 Å) | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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4HWZ
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![BU of 4hwz by Molmil](/molmil-images/mine/4hwz) | Structure of HLA-A68 complexed with an HIV derived peptide | Descriptor: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2012-11-09 | Release date: | 2013-10-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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3ORW
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![BU of 3orw by Molmil](/molmil-images/mine/3orw) | Crystal structure of thermophilic phosphotriesterase from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | Zheng, B.S, Yu, S.S, Zhang, Y, Lou, Z.Y, Feng, Y. | Deposit date: | 2010-09-07 | Release date: | 2011-09-21 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of thermophilic phosphotriesterase from Geobacillus kaustophilus HTA426 To be Published
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3L5R
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3L5U
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3L5S
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3L5V
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3L5P
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5I2D
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![BU of 5i2d by Molmil](/molmil-images/mine/5i2d) | Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo | Descriptor: | DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Feng, Y, Zhang, Y, Ebright, R.H. | Deposit date: | 2016-02-08 | Release date: | 2016-06-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.405 Å) | Cite: | Structural basis of transcription activation. Science, 352, 2016
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1L3K
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![BU of 1l3k by Molmil](/molmil-images/mine/1l3k) | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | Descriptor: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | Authors: | Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. | Deposit date: | 2002-02-27 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Res., 30, 2002
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1K4V
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![BU of 1k4v by Molmil](/molmil-images/mine/1k4v) | 1.53 A Crystal Structure of the Beta-Galactoside-alpha-1,3-galactosyltransferase in Complex with UDP | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | Authors: | Boix, E, Swaminathan, G.J, Zhang, Y, Natesh, R, Brew, K, Acharya, K.R. | Deposit date: | 2001-10-09 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus. J.Biol.Chem., 276, 2001
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5HN7
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5HNA
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5HN8
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![BU of 5hn8 by Molmil](/molmil-images/mine/5hn8) | Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1182 | Descriptor: | 2-{[3-hydroxy-5-(octyloxy)benzyl]sulfanyl}benzoic acid, Farnesyl pyrophosphate synthase, putative, ... | Authors: | Liu, Y.-L, Zhang, Y, Oldfield, E. | Deposit date: | 2016-01-18 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016
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5HN9
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8H9I
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![BU of 8h9i by Molmil](/molmil-images/mine/8h9i) | Human ATP synthase F1 domain, state2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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