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8JPA
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BU of 8jpa by Molmil
De novo design cavitated protein without predefined topology
Descriptor: De novo design cavitated protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-06-11
Release date:2023-06-28
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:De novo design of cavity-containing proteins with a backbone-centered neural network energy function.
Structure, 32, 2024
8JSW
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BU of 8jsw by Molmil
Human VMAT2 complex with serotonin
Descriptor: SEROTONIN, Synaptic vesicular amine transporter
Authors:Jiang, D.H, Wu, D.
Deposit date:2023-06-20
Release date:2023-11-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Transport and inhibition mechanisms of human VMAT2.
Nature, 626, 2024
8JTC
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BU of 8jtc by Molmil
Human VMAT2 complex with reserpine
Descriptor: Synaptic vesicular amine transporter, reserpine
Authors:Jiang, D.H, Wu, D.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Transport and inhibition mechanisms of human VMAT2.
Nature, 626, 2024
8JT9
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BU of 8jt9 by Molmil
Human VMAT2 complex with ketanserin
Descriptor: 3-[2-[4-(4-fluorophenyl)carbonylpiperidin-1-yl]ethyl]-1~{H}-quinazoline-2,4-dione, Synaptic vesicular amine transporter
Authors:Jiang, D.H, Wu, D.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Transport and inhibition mechanisms of human VMAT2.
Nature, 626, 2024
8JTA
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BU of 8jta by Molmil
Human VMAT2 complex with tetrabenazine
Descriptor: Synaptic vesicular amine transporter, tetrabenazine
Authors:Jiang, D.H, Wu, D.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Transport and inhibition mechanisms of human VMAT2.
Nature, 626, 2024
8J1X
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BU of 8j1x by Molmil
A near-infrared fluorescent protein of de novo backbone design
Descriptor: near-infrared fluorescent protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-04-13
Release date:2023-10-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024
8J1W
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BU of 8j1w by Molmil
A near-infrared fluorescent protein of de novo backbone design
Descriptor: near-infrared fluorescent protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-04-13
Release date:2023-10-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024
7DJS
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BU of 7djs by Molmil
Crystal structure of isopiperitenol dehydrogenase from Pseudomonas aeruginosa complexed with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family oxidoreductase
Authors:Zhan, J.R, Zheng, Y.C.
Deposit date:2020-11-21
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery and Engineering of Bacterial (-)-Isopiperitenol Dehydrogenases to Enhance (-)-Menthol Precursor Biosynthesis.
Adv.Synth.Catal., 363, 2021
7DKK
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BU of 7dkk by Molmil
De novo design protein XM2H
Descriptor: De novo design protein XM2H
Authors:Bin, H.
Deposit date:2020-11-24
Release date:2021-12-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A backbone-centred energy function of neural networks for protein design.
Nature, 602, 2022
7DKO
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BU of 7dko by Molmil
De novo design protein AM2M
Descriptor: de novo designed protein AM2M
Authors:Bin, H.
Deposit date:2020-11-25
Release date:2021-12-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A backbone-centred energy function of neural networks for protein design.
Nature, 602, 2022
7DMF
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BU of 7dmf by Molmil
A de novo protein that rigidly extends the structure of tVHS-like domain in tepsin with a new designed domain
Descriptor: Designed protein EXTD-3
Authors:Xu, Y.
Deposit date:2020-12-03
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:A backbone-centred energy function of neural networks for protein design.
Nature, 602, 2022
7EGN
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BU of 7egn by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2021-03-24
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:H-Bonding Networks Dictate the Molecular Mechanism of H2O2 Activation by P450
Acs Catalysis, 11, 2021
7V6X
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BU of 7v6x by Molmil
Crystal structure of HPPD complexed with Y18556
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, 5-methyl-3-[(2-methylphenyl)methyl]-6-[(1~{R},2~{S})-2-oxidanyl-6-oxidanylidene-cyclohexyl]carbonyl-1,2,3-benzotriazin-4-one, COBALT (II) ION
Authors:Lin, H.Y, Yang, G.F.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pharmacophore-Oriented Discovery of Novel 1,2,3-Benzotriazine-4-one Derivatives as Potent 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
J.Agric.Food Chem., 70, 2022
7V90
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BU of 7v90 by Molmil
Telomeric mononucleosome
Descriptor: DNA (145-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-24
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7VA4
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BU of 7va4 by Molmil
Telomeric tetranucleosome in open state
Descriptor: DNA (539-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-27
Release date:2022-07-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9J
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BU of 7v9j by Molmil
Telomeric trinucleosome
Descriptor: DNA (408-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-25
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9S
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BU of 7v9s by Molmil
Telomeric trinucleosome in open state
Descriptor: DNA (408-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-26
Release date:2022-07-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9C
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BU of 7v9c by Molmil
Telomeric Dinucleosome in open state
Descriptor: DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-24
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V96
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BU of 7v96 by Molmil
Telomeric Dinucleosome
Descriptor: DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-24
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7WKS
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BU of 7wks by Molmil
Apo state of AtPIN3
Descriptor: Auxin efflux carrier component 3
Authors:Su, N.
Deposit date:2022-01-11
Release date:2022-08-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
7WKW
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BU of 7wkw by Molmil
NPA bound state of AtPIN3
Descriptor: 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3
Authors:Su, N.
Deposit date:2022-01-11
Release date:2022-08-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
7V9K
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BU of 7v9k by Molmil
Telomeric tetranucleosome
Descriptor: DNA (539-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Soman, A.
Deposit date:2021-08-25
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7Y63
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BU of 7y63 by Molmil
ApoSIDT2-pH7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2, ...
Authors:Gong, D.S.
Deposit date:2022-06-18
Release date:2023-06-21
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.
Nat Commun, 14, 2023
7Y68
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BU of 7y68 by Molmil
SIDT2-pH5.5 plus miRNA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2, ...
Authors:Gong, D.S.
Deposit date:2022-06-18
Release date:2023-06-21
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.
Nat Commun, 14, 2023
7Y69
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BU of 7y69 by Molmil
ApoSIDT2-pH5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2, ...
Authors:Gong, D.S.
Deposit date:2022-06-18
Release date:2023-06-21
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.
Nat Commun, 14, 2023

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数据于2024-10-16公开中

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