8JP0

structure of human sodium-calciumexchanger NCX1

Summary for 8JP0

• Entry DOI: 10.2210/pdb8jp0/pdb
• EMDB information: 36465
• Descriptor: Sodium/calcium exchanger 1, 2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline (2 entities in total)
• Functional Keywords: sodium/calcium exchanger, membrane protein, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 105165.64

Authors

Dong, Y.,Zhao, Y. (deposition date: 2023-06-09, release date: 2024-01-03, Last modification date: 2024-01-24)

• Primary citation: Dong, Y.,Yu, Z.,Li, Y.,Huang, B.,Bai, Q.,Gao, Y.,Chen, Q.,Li, N.,He, L.,Zhao, Y.; Structural insight into the allosteric inhibition of human sodium-calcium exchanger NCX1 by XIP and SEA0400.; Embo J., 43:14-31, 2024; PubMed: 38177313; DOI: 10.1038/s44318-023-00013-0

Experimental method

ELECTRON MICROSCOPY (3.5 Å)