Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1CDY
DownloadVisualize
BU of 1cdy by Molmil
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER
Descriptor: T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
4DJH
DownloadVisualize
BU of 4djh by Molmil
Structure of the human kappa opioid receptor in complex with JDTic
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CITRIC ACID, ...
Authors:Wu, H, Wacker, D, Katritch, V, Mileni, M, Han, G.W, Vardy, E, Liu, W, Thompson, A.A, Huang, X.P, Carroll, F.I, Mascarella, S.W, Westkaemper, R.B, Mosier, P.D, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2012-02-01
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:tructure of the human kappa-opioid receptor in complex with JDTic
Nature, 485, 2012
1K4B
DownloadVisualize
BU of 1k4b by Molmil
STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor: 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3'
Authors:Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1K4A
DownloadVisualize
BU of 1k4a by Molmil
STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor: 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3'
Authors:Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1T4L
DownloadVisualize
BU of 1t4l by Molmil
Solution structure of double-stranded RNA binding domain of S. cerevisiae RNase III (Rnt1p) in complex with the 5' terminal RNA hairpin of snR47 precursor
Descriptor: 5' terminal hairpin of snR47 precursor, Ribonuclease III
Authors:Wu, H, Henras, A, Chanfreau, G, Feigon, J.
Deposit date:2004-04-29
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.
Proc.Natl.Acad.Sci.USA, 101, 2004
6IDE
DownloadVisualize
BU of 6ide by Molmil
Crystal structure of the Vibrio cholera VqmA-Ligand-DNA complex provides molecular mechanisms for drug design
Descriptor: 3,5-dimethylpyrazin-2-ol, DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*AP*AP*TP*CP*CP*CP*CP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*TP*TP*TP*CP*CP*CP*CP*CP*CP*T)-3'), ...
Authors:Wu, H, Li, M.J, Guo, H.J, Zhou, H, Li, B, Xu, Q, Xu, C.Y, Yu, F, He, J.H.
Deposit date:2018-09-09
Release date:2019-01-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of theVibrio choleraeVqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design.
J. Biol. Chem., 294, 2019
6KJU
DownloadVisualize
BU of 6kju by Molmil
Huge conformation shift of Vibrio cholerae VqmA dimer in the absence of target DNA provides insight into DNA-binding mechanisms of LuxR-type receptors
Descriptor: 3,5-dimethylpyrazin-2-ol, Helix-turn-helix transcriptional regulator
Authors:Wu, H, Li, M.J, Guo, H.J, Zhou, H, Wang, W.W, Xu, Q, Xu, C.Y, Yu, F, He, J.H.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors.
Biochem.Biophys.Res.Commun., 520, 2019
2MVN
DownloadVisualize
BU of 2mvn by Molmil
Solution structure of eEF1Bdelta CAR domain in TCTP-bound state
Descriptor: Elongation factor 1-delta
Authors:Wu, H, Feng, Y.
Deposit date:2014-10-09
Release date:2015-02-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
2MVM
DownloadVisualize
BU of 2mvm by Molmil
Solution structure of eEF1Bdelta CAR domain
Descriptor: Elongation factor 1-delta
Authors:Wu, H, Feng, Y.
Deposit date:2014-10-09
Release date:2015-02-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
2N51
DownloadVisualize
BU of 2n51 by Molmil
NMR structure of the C-terminal region of human eukaryotic elongation factor 1B
Descriptor: Elongation factor 1-delta
Authors:Wu, H, Feng, Y.
Deposit date:2015-07-02
Release date:2016-05-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-terminal region of human eukaryotic elongation factor 1B delta.
J.Biomol.Nmr, 64, 2016
2P89
DownloadVisualize
BU of 2p89 by Molmil
Solution structure of the 3' pseudouridyation pocket of U65 snoRNA with bound substrate
Descriptor: 28S rRNA, U65 H/ACA snoRNA
Authors:Wu, H, Feigon, J.
Deposit date:2007-03-22
Release date:2007-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QTF
DownloadVisualize
BU of 2qtf by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus
Descriptor: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
Authors:Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2QTH
DownloadVisualize
BU of 2qth by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP
Descriptor: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
Authors:Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
4OR2
DownloadVisualize
BU of 4or2 by Molmil
Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, CHOLESTEROL, ...
Authors:Wu, H, Wang, C, Gregory, K.J, Han, G.W, Cho, H.P, Xia, Y, Niswender, C.M, Katritch, V, Cherezov, V, Conn, P.J, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2014-02-10
Release date:2014-03-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
7VU5
DownloadVisualize
BU of 7vu5 by Molmil
Structure of the transmembrane domain of the CD28 dimer
Descriptor: T-cell-specific surface glycoprotein CD28
Authors:Wu, H, Cao, R, Wen, M, Ouyang, B.
Deposit date:2021-11-01
Release date:2022-03-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural characterization of a dimerization interface in the CD28 transmembrane domain.
Structure, 30, 2022
2FYT
DownloadVisualize
BU of 2fyt by Molmil
Human HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae) protein
Descriptor: Protein arginine N-methyltransferase 3, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-02-08
Release date:2006-03-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human HMT1 hnRNP methyltransferase-like 3 in complex with SAH.
To be Published
3LYI
DownloadVisualize
BU of 3lyi by Molmil
PWWP Domain of Human Bromodomain-Containing Protein 1
Descriptor: Bromodomain-containing protein 1, CYSTEINESULFONIC ACID
Authors:Lam, R, Zeng, H, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2010-02-26
Release date:2010-03-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
2RFI
DownloadVisualize
BU of 2rfi by Molmil
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide
Descriptor: Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ...
Authors:Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2007-09-30
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
5HZM
DownloadVisualize
BU of 5hzm by Molmil
Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae)
Descriptor: Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION
Authors:DONG, A, ZENG, H, WALKER, J.R, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, MIN, J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2016-02-02
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
4P7A
DownloadVisualize
BU of 4p7a by Molmil
Crystal Structure of human MLH1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Mlh1, MAGNESIUM ION, ...
Authors:Tempel, W, Lam, R, Zeng, H, Walker, J.R, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2014-03-26
Release date:2014-04-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome.
Acta Crystallogr.,Sect.F, 71, 2015
5WOD
DownloadVisualize
BU of 5wod by Molmil
De Novo Design of Covalently Constrained Meso-size Protein Scaffolds with Unique Tertiary Structures
Descriptor: 38-mer peptide
Authors:Wu, H, Wu, Y, DeGrado, W.F.
Deposit date:2017-08-01
Release date:2017-10-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1FB9
DownloadVisualize
BU of 1fb9 by Molmil
EFFECTS OF S-SULFONATION ON THE SOLUTION STRUCTURE OF SALMON CALCITONIN
Descriptor: CALCITONIN ANALOGUE
Authors:Wu, H, Mao, J, Wang, Y, Dou, H.
Deposit date:2000-07-14
Release date:2003-07-01
Last modified:2018-06-27
Method:SOLUTION NMR
Cite:Solution structure and biological activity of recombinant salmon calcitonin S-sulfonated analog
Biochem.Biophys.Res.Commun., 306, 2003
4QQK
DownloadVisualize
BU of 4qqk by Molmil
Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS
Descriptor: (5S)-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}-N~6~-carbamimidoyl-L-lysine, GLYCEROL, Protein arginine N-methyltransferase 6, ...
Authors:Dong, A, Zeng, H, He, H, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
1WM8
DownloadVisualize
BU of 1wm8 by Molmil
Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures
Descriptor: Neurotoxin BmP03
Authors:Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X.
Deposit date:2004-07-05
Release date:2004-07-27
Last modified:2018-04-18
Method:SOLUTION NMR
Cite:Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch
Acta Chim.Sinica, 58, 2000
1WT8
DownloadVisualize
BU of 1wt8 by Molmil
Solution Structure of BmP08 from the Venom of Scorpion Buthus martensii Karsch, 20 structures
Descriptor: Neurotoxin BmK X
Authors:Wu, H, Chen, X, Tong, X, Li, Y, Zhang, N, Wu, G.
Deposit date:2004-11-17
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of BmP08, a novel short-chain scorpion toxin from Buthus martensi Karsch.
Biochem.Biophys.Res.Commun., 330, 2005

222624

数据于2024-07-17公开中

PDB statisticsPDBj update infoContact PDBjnumon