6V4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v4j by Molmil](/molmil-images/mine/6v4j) | Structure of TrkH-TrkA in complex with ATP | Descriptor: | Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | Authors: | Zhou, M, Zhang, H. | Deposit date: | 2019-11-27 | Release date: | 2020-02-12 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
|
|
6V4K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v4k by Molmil](/molmil-images/mine/6v4k) | Structure of TrkH-TrkA in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Potassium transporter peripheral membrane component, Trk system potassium uptake protein | Authors: | Zhou, M, Zhang, H. | Deposit date: | 2019-11-27 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.53004146 Å) | Cite: | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
|
|
6V4L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v4l by Molmil](/molmil-images/mine/6v4l) | Structure of TrkH-TrkA in complex with ATPgammaS | Descriptor: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | Authors: | Zhou, M, Zhang, H. | Deposit date: | 2019-11-27 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
|
|
8K5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k5r by Molmil](/molmil-images/mine/8k5r) | CDK9/cyclin T1 in complex with KB-0742 | Descriptor: | (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 | Authors: | Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.751 Å) | Cite: | Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. J.Med.Chem., 66, 2023
|
|
1J95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j95 by Molmil](/molmil-images/mine/1j95) | |
1S5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s5h by Molmil](/molmil-images/mine/1s5h) | Potassium Channel Kcsa-Fab Complex T75C mutant in K+ | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ... | Authors: | Mackinnon, R, Zhou, M. | Deposit date: | 2004-01-20 | Release date: | 2004-05-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution. J.Mol.Biol., 338, 2004
|
|
4WJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wja by Molmil](/molmil-images/mine/4wja) | Crystal Structure of PAXX | Descriptor: | Uncharacterized protein C9orf142 | Authors: | Xing, M, Yang, M, Huo, W, Feng, F, Wei, L, Ning, S, Yan, Z, Li, W, Wang, Q, Hou, M, Dong, C, Guo, R, Gao, G, Ji, J, Lan, L, Liang, H, Xu, D. | Deposit date: | 2014-09-29 | Release date: | 2015-03-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun, 6, 2015
|
|
8GS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gs3 by Molmil](/molmil-images/mine/8gs3) | Cryo-EM structure of human Neuroligin 3 | Descriptor: | Neuroligin-3 | Authors: | Zhang, H, Zhang, Z, Hou, M. | Deposit date: | 2022-09-04 | Release date: | 2023-09-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders. Front Endocrinol, 13, 2022
|
|
8GS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gs4 by Molmil](/molmil-images/mine/8gs4) | Cryo-EM structure of human Neuroligin 2 | Descriptor: | Neuroligin-2 | Authors: | Zhang, H, Zhang, Z, Hou, M. | Deposit date: | 2022-09-04 | Release date: | 2023-03-01 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders. Front Endocrinol, 13, 2022
|
|
5EUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5euf by Molmil](/molmil-images/mine/5euf) | The crystal structure of a protease from Helicobacter pylori | Descriptor: | GLYCEROL, Protease, ZINC ION | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-11-18 | Release date: | 2015-12-02 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of a protease from Helicobacter pylori To Be Published
|
|
7TBS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tbs by Molmil](/molmil-images/mine/7tbs) | Crystal Structure of the Glutaredoxin 2 from Francisella tularensis | Descriptor: | CHLORIDE ION, Glutaredoxin 2, SULFATE ION | Authors: | Kim, Y, Zhou, M, Grimshaw, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-12-22 | Release date: | 2022-01-05 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structure of the Glutaredoxin 2 from Francisella tularensis To Be Published
|
|
3ERM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3erm by Molmil](/molmil-images/mine/3erm) | |
1Y71
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y71 by Molmil](/molmil-images/mine/1y71) | X-ray crystal structure of kinase-associated protein B from Bacillus cereus | Descriptor: | Kinase-associated protein B | Authors: | Osipiuk, J, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-07 | Release date: | 2005-01-18 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-ray crystal structure of kinase-associated protein B from Bacillus cereus To be Published
|
|
1Y12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y12 by Molmil](/molmil-images/mine/1y12) | |
2ITD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2itd by Molmil](/molmil-images/mine/2itd) | Potassium Channel KcsA-Fab complex in Barium Chloride | Descriptor: | BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
|
|
1Y5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y5e by Molmil](/molmil-images/mine/1y5e) | Crystal structure of Molybdenum cofactor biosynthesis protein B | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, IMIDAZOLE, Molybdenum cofactor biosynthesis protein B | Authors: | Chang, C, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-02 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Molybdenum cofactor biosynthesis protein B TO BE PUBLISHED
|
|
2ITC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2itc by Molmil](/molmil-images/mine/2itc) | Potassium Channel KcsA-Fab complex in Sodium Chloride | Descriptor: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
|
|
2IQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2iqt by Molmil](/molmil-images/mine/2iqt) | Crystal Structure of Fructose-Bisphosphate Aldolase, Class I from Porphyromonas gingivalis | Descriptor: | Fructose-bisphosphate aldolase class 1 | Authors: | Kim, Y, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-10-14 | Release date: | 2006-11-14 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Crystal Structure of Fructose-Bisphosphate Aldolase, Class I from Porphyromonas gingivalis To be Published
|
|
6DGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dgi by Molmil](/molmil-images/mine/6dgi) | |
4MA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ma0 by Molmil](/molmil-images/mine/4ma0) | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP | Descriptor: | ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-15 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.982 Å) | Cite: | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP To be Published
|
|
4MAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mam by Molmil](/molmil-images/mine/4mam) | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP | Descriptor: | GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Phosphoribosylaminoimidazole carboxylase, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-16 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.474 Å) | Cite: | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP To be Published
|
|
4M9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m9u by Molmil](/molmil-images/mine/4m9u) | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | ACETATE ION, CHLORIDE ION, FORMIC ACID, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-15 | Release date: | 2013-08-28 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 To be Published
|
|
4MA5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ma5 by Molmil](/molmil-images/mine/4ma5) | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ATP analog, AMP-PNP. | Descriptor: | FORMIC ACID, GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-15 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.809 Å) | Cite: | The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ATP analog, AMP-PNP. To be Published
|
|
3O6D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o6d by Molmil](/molmil-images/mine/3o6d) | Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni in complex with pyridoxine-5'-phosphate | Descriptor: | PHOSPHATE ION, PYRIDOXINE-5'-PHOSPHATE, Pyridoxine 5'-phosphate synthase | Authors: | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-28 | Release date: | 2010-08-11 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-ray crystal structure of pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni. To be Published
|
|
7TAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tak by Molmil](/molmil-images/mine/7tak) | Structure of a NAT transporter | Descriptor: | GUANINE, Putative membrane protein PurT | Authors: | Weng, J, Zhou, X, Ren, Z, Chen, K, Zhou, M. | Deposit date: | 2021-12-21 | Release date: | 2023-01-25 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.79828 Å) | Cite: | Insight into the mechanism of H + -coupled nucleobase transport. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|