3CGZ
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3CGY
| Crystal Structure of Salmonella Sensor Kinase PhoQ catalytic domain in complex with radicicol | Descriptor: | RADICICOL, Virulence sensor histidine kinase phoQ | Authors: | Guarnieri, M.T, Zhang, L, Shen, J, Zhao, R. | Deposit date: | 2008-03-06 | Release date: | 2008-05-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ. J.Mol.Biol., 379, 2008
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3E66
| Crystal structure of the beta-finger domain of yeast Prp8 | Descriptor: | PRP8 | Authors: | Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R. | Deposit date: | 2008-08-14 | Release date: | 2008-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3N3Z
| Crystal structure of PDE9A (E406A) mutant in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, CHLORIDE ION, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | Authors: | Hou, J, Luo, H.-B, Chen, Y, Xu, J, Zhao, R, Zou, L. | Deposit date: | 2010-05-21 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of PDE9A (E406A) mutation in complex with IBMX To be Published
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1OOI
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1OOH
| Complex of Drosophila odorant binding protein LUSH with butanol | Descriptor: | 1-BUTANOL, ACETATE ION, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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1OOF
| Complex of Drosophila odorant binding protein LUSH with ethanol | Descriptor: | ACETATE ION, ETHANOL, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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1OOG
| Complex of Drosophila odorant binding protein LUSH with propanol | Descriptor: | ACETATE ION, N-PROPANOL, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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8JED
| Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors | Descriptor: | mRNA-capping enzyme regulatory subunit OPG124 | Authors: | Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X. | Deposit date: | 2023-05-15 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors. Int.J.Biol.Macromol., 253, 2023
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3QI3
| Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691 | Descriptor: | 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Hou, J, Xu, J, Liu, M, Zhao, R, Lou, H, Ke, H. | Deposit date: | 2011-01-26 | Release date: | 2011-04-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine. Plos One, 6, 2011
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3QI4
| Crystal structure of PDE9A(Q453E) in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Hou, J, Xu, J, Liu, M, Zhao, R, Lou, H, Ke, H. | Deposit date: | 2011-01-26 | Release date: | 2011-04-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine. Plos One, 6, 2011
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8W2O
| Yeast U1 snRNP with humanized U1C Zinc-Finger domain | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ... | Authors: | Shi, S.S, Kuang, Z.L, Zhao, R. | Deposit date: | 2024-02-20 | Release date: | 2024-05-15 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. Rna, 30, 2024
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6N7P
| S. cerevisiae spliceosomal E complex (UBC4) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Nuclear cap-binding protein complex subunit 1, Nuclear cap-binding protein subunit 2, ... | Authors: | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | Deposit date: | 2018-11-27 | Release date: | 2019-09-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A unified mechanism for intron and exon definition and back-splicing. Nature, 573, 2019
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6N7R
| Saccharomyces cerevisiae spliceosomal E complex (ACT1) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ... | Authors: | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | Deposit date: | 2018-11-28 | Release date: | 2019-09-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A unified mechanism for intron and exon definition and back-splicing. Nature, 573, 2019
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6BK8
| S. cerevisiae spliceosomal post-catalytic P complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ... | Authors: | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | Deposit date: | 2017-11-07 | Release date: | 2018-02-21 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the yeast spliceosomal postcatalytic P complex. Science, 358, 2017
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5WWP
| Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13) | Descriptor: | ORF1ab, SULFATE ION, ZINC ION | Authors: | Hao, W, Wojdyla, J.A, Zhao, R, Han, R, Das, R, Zlatev, I, Manoharan, M, Wang, M, Cui, S. | Deposit date: | 2017-01-03 | Release date: | 2017-07-05 | Last modified: | 2021-09-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of Middle East respiratory syndrome coronavirus helicase PLoS Pathog., 13, 2017
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2G6Q
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6N7X
| S. cerevisiae U1 snRNP | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ... | Authors: | Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R. | Deposit date: | 2018-11-28 | Release date: | 2019-07-24 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun, 8, 2017
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7VYV
| Cryo-EM structure of Depo32, a Klebsiella phage depolymerase targets the K2 serotype K. pneumoniae | Descriptor: | Depolymerase | Authors: | Cai, R, Ren, Z, Zhao, R, Wang, X, Guo, Z, Du, R, Han, W, Ru, H, Gu, J. | Deposit date: | 2021-11-15 | Release date: | 2023-08-30 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Structural biology and functional features of phage-derived depolymerase Depo32 on Klebsiella pneumoniae with K2 serotype capsular polysaccharides. Microbiol Spectr, 11, 2023
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7VZ3
| Cryo-EM structure of Depo32, a Klebsiella phage depolymerase targets the K2 serotype K. pneumoniae | Descriptor: | Depolymerase | Authors: | Cai, R, Ren, Z, Zhao, R, Wang, X, Guo, Z, Du, R, Han, W, Ru, H, Gu, J. | Deposit date: | 2021-11-15 | Release date: | 2023-08-30 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structural biology and functional features of phage-derived depolymerase Depo32 on Klebsiella pneumoniae with K2 serotype capsular polysaccharides. Microbiol Spectr, 11, 2023
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2L6J
| Tah1 complexed by MEEVD | Descriptor: | C-terminus Hsp90 chaperone peptide MEEVD, TPR repeat-containing protein associated with Hsp90 | Authors: | Jimenez, B, Ugwu, F, Zhao, R, Orti, L, Houry, W.A, Pineda-Lucena, A. | Deposit date: | 2010-11-22 | Release date: | 2011-12-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90. J.Biol.Chem., 287, 2012
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2P8R
| Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 carrying R2303K mutant | Descriptor: | Pre-mRNA-splicing factor Prp8 | Authors: | Zhang, L, Shen, J, Guarnieri, M.T, Heroux, A, Yang, K, Zhao, R. | Deposit date: | 2007-03-22 | Release date: | 2007-05-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants Protein Sci., 16, 2007
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2P87
| Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 | Descriptor: | Pre-mRNA-splicing factor Prp8 | Authors: | Zhang, L, Shen, J, Guarnieri, M.T, Heroux, A, Yang, K, Zhao, R. | Deposit date: | 2007-03-21 | Release date: | 2007-05-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants Protein Sci., 16, 2007
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8J5J
| The crystal structure of bat coronavirus RsYN04 RBD bound to the antibody S43 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nano antibody S43 | Authors: | Zhao, R.C, Niu, S, Han, P, Qi, J.X, Gao, G.F, Wang, Q.H. | Deposit date: | 2023-04-23 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus. Zool.Res., 44, 2023
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8XS3
| Structure of MPXV B6 and D68 fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D68_heavy chain, ... | Authors: | wu, L.L, Sun, J.Q. | Deposit date: | 2024-01-08 | Release date: | 2024-06-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections. Nat Commun, 15, 2024
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