2L6J

Tah1 complexed by MEEVD

Summary for 2L6J

DescriptorTPR repeat-containing protein associated with Hsp90, C-terminus Hsp90 chaperone peptide MEEVD (2 entities in total)
Functional Keywordstetratricopeptide repeat (tpr), hsp90 co-factor, protein binding
Biological sourceSaccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
More
Cellular locationCytoplasm P25638
Total number of polymer chains2
Total molecular weight13145.8
Authors
Jimenez, B.,Ugwu, F.,Zhao, R.,Orti, L.,Houry, W.A.,Pineda-Lucena, A. (deposition date: 2010-11-22, release date: 2011-12-28, Last modification date: 2012-05-09)
Primary citation
Jimenez, B.,Ugwu, F.,Zhao, R.,Orti, L.,Makhnevych, T.,Pineda-Lucena, A.,Houry, W.A.
Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90.
J.Biol.Chem., 287:5698-5709, 2012
PubMed: 22179618 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M111.287458
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers00.1%11.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures