1H47
| Structures of MECP synthase in complex with (i) CMP and (ii) CMP and product | Descriptor: | 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-MONOPHOSPHATE, GERANYL DIPHOSPHATE, ... | Authors: | Kemp, L.E, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2003-02-24 | Release date: | 2004-10-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods Acta Crystallogr.,Sect.D, 61, 2005
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6N65
| KRAS G-quadruplex G16T mutant. | Descriptor: | KRAS G-quadruplex G16T mutant, POTASSIUM ION | Authors: | Schmidberger, J.W, Ou, A, Smith, N.M, Iyer, K.S, Bond, C.S. | Deposit date: | 2018-11-25 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A pi-stacking interactions for small-molecule recognition. Nucleic Acids Res., 48, 2020
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1GY8
| Trypanosoma brucei UDP-galactose 4' epimerase | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE 4-EPIMERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Shaw, M.P, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-04-21 | Release date: | 2003-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-Resolution Crystal Structure of Trypanosoma Brucei Udp-Galactose 4'-Epimerase: A Potential Target for Structure-Based Development of Novel Trypanocides Mol.Biochem.Parasitol., 126, 2003
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1H48
| The structure of 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase in complex with CMP and product | Descriptor: | 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Kemp, L.E, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2003-02-24 | Release date: | 2004-12-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods Acta Crystallogr.,Sect.D, 61, 2005
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1H3M
| Structure of 4-diphosphocytidyl-2C-methyl-D-erythritol synthetase | Descriptor: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLORIDE ION, PENTANE-1,5-DIAMINE | Authors: | Kemp, L.E, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-09-10 | Release date: | 2003-08-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Acta Crystallogr.,Sect.D, 59, 2003
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1GX1
| Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase | Descriptor: | 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Kemp, L.E, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-03-26 | Release date: | 2002-04-03 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of 2C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase: An Essential Enzyme for Isoprenoid Biosynthesis and Target for Antimicrobial Drug Development Proc.Natl.Acad.Sci.USA, 99, 2002
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6EEN
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4MTT
| Ni- and Zn-bound GloA2 at low resolution | Descriptor: | CHLORIDE ION, GLYCEROL, Lactoylglutathione lyase, ... | Authors: | Bythell-Douglas, R, Bond, C.S. | Deposit date: | 2013-09-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity. Chemistry, 21, 2015
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4WII
| HUMAN SPLICING FACTOR, CONSTRUCT 3 | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Splicing factor, ... | Authors: | lee, M, bond, c.s. | Deposit date: | 2014-09-26 | Release date: | 2015-04-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation. Nucleic Acids Res., 43, 2015
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4MTQ
| Ni-bound GloA2 | Descriptor: | Lactoylglutathione lyase, NICKEL (II) ION, SUCCINIC ACID | Authors: | Bythell-Douglas, R, Bond, C.S. | Deposit date: | 2013-09-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity. Chemistry, 21, 2015
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4MTR
| Zn-bound GloA2 | Descriptor: | 1,2-ETHANEDIOL, Lactoylglutathione lyase, ZINC ION | Authors: | Bythell-Douglas, R, Bond, C.S. | Deposit date: | 2013-09-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity. Chemistry, 21, 2015
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4WIK
| HUMAN SPLICING FACTOR, CONSTRUCT 2 | Descriptor: | Splicing factor, proline- and glutamine-rich | Authors: | lee, M, bond, c.s. | Deposit date: | 2014-09-26 | Release date: | 2015-04-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation. Nucleic Acids Res., 43, 2015
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4MTS
| Ni- and Zn-bound GloA2 at high resolution | Descriptor: | GLYCEROL, Lactoylglutathione lyase, NICKEL (II) ION, ... | Authors: | Bythell-Douglas, R, Bond, C.S. | Deposit date: | 2013-09-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity. Chemistry, 21, 2015
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7MMY
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5IFN
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5IFM
| Human NONO (p54nrb) Homodimer | Descriptor: | CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ... | Authors: | Knott, G.J, Bond, C.S. | Deposit date: | 2016-02-26 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry. Acta Crystallogr D Struct Biol, 72, 2016
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7LRQ
| Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region | Descriptor: | CHLORIDE ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ... | Authors: | Marshall, A.C, Bond, C.S, Mohnen, I. | Deposit date: | 2021-02-17 | Release date: | 2021-05-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains. J.Biol.Chem., 298, 2022
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3SDE
| Crystal structure of a paraspeckle-protein heterodimer, PSPC1/NONO | Descriptor: | 1,2-ETHANEDIOL, Non-POU domain-containing octamer-binding protein, Paraspeckle component 1 | Authors: | Passon, D.M, Lee, M, Bond, C.S. | Deposit date: | 2011-06-09 | Release date: | 2012-03-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation. Proc.Natl.Acad.Sci.USA, 109, 2012
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6ART
| Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with cesium ions | Descriptor: | Acetyl-CoA acetyltransferase, CESIUM ION, CHLORIDE ION, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-23 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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4HP2
| Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution | Descriptor: | DIMETHYLFORMAMIDE, Thiostrepton, diethyl ether | Authors: | Proepper, K, Holstein, J.J, Huebschle, C.B, Bond, C.S, Dittrich, B. | Deposit date: | 2012-10-23 | Release date: | 2013-10-02 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (0.64 Å) | Cite: | Invariom refinement of a new monoclinic solvate of thiostrepton at 0.64 angstrom resolution. Acta Crystallogr.,Sect.D, 69, 2013
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6ARE
| Aspergillus fumigatus Cytosolic Thiolase in complex with two tetrahedral reaction intermediates and ammonium ions | Descriptor: | ACETATE ION, ACETYL COENZYME *A, AMMONIUM ION, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-22 | Release date: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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6ARL
| Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with rubidium ions | Descriptor: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-22 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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6AQP
| Aspergillus fumigatus Cytosolic Thiolase: Acetylated enzyme in complex with CoA and potassium ions | Descriptor: | ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, CHLORIDE ION, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-21 | Release date: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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6ARF
| Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with potassium ions | Descriptor: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-22 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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6ARG
| Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with rubidium ions | Descriptor: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-22 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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