1GX1

Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase

Summary for 1GX1

• Entry DOI: 10.2210/pdb1gx1/pdb
• Related: 1JY8
• Descriptor: 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, ZINC ION, CYTIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: synthase, isoprenoid, lyase, isoprene biosynthesis
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 3
• Total formula weight: 53378.32

Authors

Kemp, L.E.,Bond, C.S.,Hunter, W.N. (deposition date: 2002-03-26, release date: 2002-04-03, Last modification date: 2018-02-28)

• Primary citation: Kemp, L.E.,Bond, C.S.,Hunter, W.N.; Structure of 2C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase: An Essential Enzyme for Isoprenoid Biosynthesis and Target for Antimicrobial Drug Development; Proc.Natl.Acad.Sci.USA, 99:6591-, 2002; PubMed: 11997478; DOI: 10.1073/PNAS.102679799

Experimental method

X-RAY DIFFRACTION (1.8 Å)