6ARE

Aspergillus fumigatus Cytosolic Thiolase in complex with two tetrahedral reaction intermediates and ammonium ions

Summary for 6ARE

• Entry DOI: 10.2210/pdb6are/pdb
• Related: 6AQP
• Descriptor: Acetyl-CoA acetyltransferase, acetylated enzyme, Acetyl-CoA acetyltransferase, COENZYME A, ... (8 entities in total)
• Functional Keywords: thiolase, claisen condensation, reaction intermediate, monovalent cation binding, transferase
• Biological source: Aspergillus fumigatus Af293; More
• Total number of polymer chains: 4
• Total formula weight: 167667.92

Authors

Marshall, A.C.,Bond, C.S.,Bruning, J.B. (deposition date: 2017-08-22, release date: 2018-05-30, Last modification date: 2025-04-02)

• Primary citation: Marshall, A.C.,Bond, C.S.,Bruning, J.B.; Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations; Acs Catalysis, 8(3):1973-1989, 2018; DOI: 10.1021/acscatal.7b02873

Experimental method

X-RAY DIFFRACTION (1.75 Å)