6ARE

Aspergillus fumigatus Cytosolic Thiolase in complex with two tetrahedral reaction intermediates and ammonium ions

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Acetyl-CoA acetyltransferase, acetylated enzyme	polymer	399	41049.9	2	UniProt (Q4WCL5) Pfam (PF00108) Pfam (PF02803)	Aspergillus fumigatus Af293
2	C, D (C, D)	Acetyl-CoA acetyltransferase	polymer	399	41007.8	2	UniProt (Q4WCL5) Pfam (PF00108) Pfam (PF02803)	Aspergillus fumigatus Af293
3	E, I, T (A, B, D)	COENZYME A	non-polymer		767.5	3	Chemie (COA)
4	F, J, O, V (A, B, C, D)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL) PubChem (312)
5	G, H, K, L, M... (A, B, C, D)	AMMONIUM ION	non-polymer		18.0	10	Chemie (NH4) PubChem (223)
6	N, U (C, D)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT) PubChem (175)
7	S (C)	ACETYL COENZYME *A	non-polymer		809.6	1	Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977)
8	AA, BA, Y, Z (C, D, A, B)	water	water		18.0	1360	Chemie (HOH)

Sequence modifications

A, B: 1 - 398 (UniProt: Q4WCL5)

PDB	External Database	Details
Gly 0	-	expression tag

C, D: 1 - 398 (UniProt: Q4WCL5)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164115.5
Non-Polymers*	Number of molecules	20
	Total formula weight	3552.5
All*	Total formula weight	167667.9

*Water molecules are not included.