6AQP

Aspergillus fumigatus Cytosolic Thiolase: Acetylated enzyme in complex with CoA and potassium ions

Summary for 6AQP

• Entry DOI: 10.2210/pdb6aqp/pdb
• Descriptor: Acetyl-CoA acetyltransferase, COENZYME A, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: thiolase, claisen condensation, reaction intermediate, monovalent cation binding, transferase
• Biological source: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
• Total number of polymer chains: 4
• Total formula weight: 167922.71

Authors

Marshall, A.C.,Bond, C.S.,Bruning, J.B. (deposition date: 2017-08-21, release date: 2018-05-30)

• Primary citation: Marshall, A.C.,Bond, C.S.,Bruning, J.B.; Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations; Acs Catalysis, 8(3):1973-1989, 2018; DOI: 10.1021/acscatal.7b02873

Experimental method

X-RAY DIFFRACTION (1.8 Å)