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2FDB
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BU of 2fdb by Molmil
Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c
Descriptor: Fibroblast growth factor receptor 2, fibroblast growth factor 8 isoform B
Authors:Mohammadi, M, Olsen, S.K.
Deposit date:2005-12-13
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes Dev., 20, 2006
2HYU
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BU of 2hyu by Molmil
Human Annexin A2 with heparin tetrasaccharide bound
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2HYW
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BU of 2hyw by Molmil
Human Annexin A2 with Calcium bound
Descriptor: Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2HYV
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BU of 2hyv by Molmil
Human Annexin A2 with heparin hexasaccharide bound
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystallographic analysis of calcium-dependent heparin binding to annexin A2.
J.Biol.Chem., 281, 2006
7WSO
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BU of 7wso by Molmil
Structure of a membrane protein G
Descriptor: B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, Immunoglobulin heavy constant gamma 1
Authors:Ma, X, Zhu, Y, Chen, Y, Huang, Z.
Deposit date:2022-01-30
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Cryo-EM structures of two human B cell receptor isotypes.
Science, 377, 2022
5HXG
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BU of 5hxg by Molmil
STM1697-FlhD complex
Descriptor: Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697
Authors:Li, B, Yuan, Z, Qin, L, Gu, L.
Deposit date:2016-01-30
Release date:2017-02-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystal structure of STM1697-FlhD complex
To Be Published
5IO1
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BU of 5io1 by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN Z ALPHA-1-ANTITRYPSIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1-antitrypsin
Authors:Zhou, A.
Deposit date:2016-03-08
Release date:2016-06-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Molecular Mechanism of Z alpha 1-Antitrypsin Deficiency
J. Biol. Chem., 291, 2016
2P39
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BU of 2p39 by Molmil
Crystal structure of human FGF23
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
Authors:Mohammadi, M.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
Descriptor: Fibroblast growth factor 19
Authors:Mohammadi, M.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
7U23
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BU of 7u23 by Molmil
Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form
Descriptor: Insulin-like growth factor 1 receptor, single-chain LCDV-1 viral insulin-like peptide
Authors:Kirk, N.S, Lawrence, M.C.
Deposit date:2022-02-22
Release date:2022-11-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Nat Commun, 13, 2022
3UG9
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BU of 3ug9 by Molmil
Crystal Structure of the Closed State of Channelrhodopsin
Descriptor: Archaeal-type opsin 1, Archaeal-type opsin 2, OLEIC ACID, ...
Authors:Kato, H.E, Ishitani, R, Nureki, O.
Deposit date:2011-11-02
Release date:2012-01-25
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the channelrhodopsin light-gated cation channel
Nature, 482, 2012
6RPJ
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BU of 6rpj by Molmil
A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, A non-blocking CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, ...
Authors:Gao, H, Zhou, A, Zhang, F.
Deposit date:2019-05-14
Release date:2020-07-08
Last modified:2020-11-11
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
To Be Published
7FJD
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BU of 7fjd by Molmil
Cryo-EM structure of a membrane protein(WT)
Descriptor: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
Authors:Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
Deposit date:2021-08-03
Release date:2022-07-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7FJE
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BU of 7fje by Molmil
Cryo-EM structure of a membrane protein(LL)
Descriptor: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
Authors:Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
Deposit date:2021-08-03
Release date:2022-07-27
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7FJF
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BU of 7fjf by Molmil
Cryo-EM structure of a membrane protein(CS)
Descriptor: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
Authors:Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
Deposit date:2021-08-03
Release date:2022-07-27
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7CYB
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BU of 7cyb by Molmil
Saimiri boliviensis boliviensis galectin-13 with glycerol
Descriptor: GLYCEROL, Galectin
Authors:Su, J.
Deposit date:2020-09-03
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
7CYA
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BU of 7cya by Molmil
Saimiri boliviensis boliviensis galectin-13 with lactose
Descriptor: Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.
Deposit date:2020-09-03
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
7E24
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BU of 7e24 by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase
Authors:Chen, L, Tang, J, Yuan, S.
Deposit date:2021-02-04
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7203 Å)
Cite:Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
7E28
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BU of 7e28 by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
Descriptor: Oxidoreductase
Authors:Chen, L, Tang, J, Yuan, S.
Deposit date:2021-02-05
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
7EEI
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BU of 7eei by Molmil
Structure of Rift Valley fever virus RNA-dependent RNA polymerase
Descriptor: Replicase
Authors:Wang, X, Hu, C.X.
Deposit date:2021-03-18
Release date:2021-11-17
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase.
J.Virol., 96, 2022
8WUT
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BU of 8wut by Molmil
SpCas9-MMLV RT-pegRNA-target DNA complex (initiation)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUS
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BU of 8wus by Molmil
SpCas9-MMLV RT-pegRNA-target DNA complex (termination)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUV
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BU of 8wuv by Molmil
SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUU
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BU of 8wuu by Molmil
SpCas9-pegRNA-target DNA complex (pre-initiation)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
7CN2
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BU of 7cn2 by Molmil
Subparticle refinement of human papillomavirus type 16 pesudovirus in complex with H16.001 Fab
Descriptor: Major capsid protein L1, The heavy chain variable region of H16.001 Fab fragment, The light chain variable region of H16.001 Fab fragment
Authors:He, M.Z, Li, S.W.
Deposit date:2020-07-29
Release date:2020-09-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs.
Npj Vaccines, 5, 2020

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数据于2024-10-30公开中

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