5Z3O
| Structure of Snf2-nucleosome complex in ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-01-08 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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3PUN
| Crystal structure of P domain dimer of Norovirus VA207 with Lewis y tetrasaccharide | Descriptor: | Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z. | Deposit date: | 2010-12-06 | Release date: | 2011-08-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens Plos Pathog., 7, 2011
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6E7P
| cryo-EM structure of human TRPML1 with PI35P2 | Descriptor: | (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1 | Authors: | Schmiege, P, Li, X. | Deposit date: | 2018-07-27 | Release date: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9, 2018
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6E7Z
| cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2 | Descriptor: | (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 | Authors: | Schmiege, P, Li, X. | Deposit date: | 2018-07-27 | Release date: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9, 2018
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8G05
| Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | Descriptor: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | Authors: | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | Deposit date: | 2023-01-31 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14, 2023
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5DDZ
| Crystal structure of the RTA-c10-P2 complex | Descriptor: | 60S acidic ribosomal protein P2, Ricin | Authors: | Zhu, Y, Fan, X, Wang, C, Niu, L, Li, X, Teng, M. | Deposit date: | 2015-08-25 | Release date: | 2016-09-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin Sci Rep, 6, 2016
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3T89
| Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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3T88
| Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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3T8A
| Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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6E7Y
| cryo-EM structure of human TRPML1 with PI45P2 | Descriptor: | Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Schmiege, P, Li, X. | Deposit date: | 2018-07-27 | Release date: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9, 2018
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3T8B
| Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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4JEK
| Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | Descriptor: | Dibenzothiophene desulfurization enzyme C | Authors: | Zhang, L, Duan, X.L, Zhou, D.M, Li, X. | Deposit date: | 2013-02-27 | Release date: | 2013-09-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis Acta Crystallogr.,Sect.F, 69, 2013
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5DPM
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5BXJ
| Complex of the Fk1 domain mutant A19T of FKBP51 with 4-Nitrophenol | Descriptor: | P-NITROPHENOL, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Wu, D, Tao, X, Chen, Z, Han, J, Jia, W, Li, X, Wang, Z, He, Y.X. | Deposit date: | 2015-06-09 | Release date: | 2016-05-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells J. Hazard. Mater., 307, 2016
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6GQJ
| Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 18) | Descriptor: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Mast/stem cell growth factor receptor Kit | Authors: | Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | Deposit date: | 2018-06-07 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
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1WDF
| crystal structure of MHV spike protein fusion core | Descriptor: | E2 glycoprotein | Authors: | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | Deposit date: | 2004-05-14 | Release date: | 2004-06-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE J.Biol.Chem., 279, 2004
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1WDG
| crystal structure of MHV spike protein fusion core | Descriptor: | E2 glycoprotein | Authors: | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | Deposit date: | 2004-05-14 | Release date: | 2004-06-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE J.Biol.Chem., 279, 2004
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8T05
| Structure of Ciona Myomaker bound to Fab1A1 | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T07
| Structure of mouse Myomaker mutant-Y118A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T06
| Structure of mouse Myomaker mutant-R107A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T03
| Structure of mouse Myomaker bound to Fab18G7 in detergent | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T04
| Structure of mouse Myomaker bound to Fab18G7 in nanodiscs | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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3QXL
| Crystal structure of the CDC25 Domain from Ral-specific Guanine-nucleotide Exchange Factor RalGPS1a | Descriptor: | Ras-specific guanine nucleotide-releasing factor RalGPS1 | Authors: | Peng, W, Xu, J, Guan, X, Sun, Y, Li, X, Zhang, X.C, Rao, Z. | Deposit date: | 2011-03-02 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.237 Å) | Cite: | Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a. Protein Cell, 2, 2011
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4Q77
| Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus | Descriptor: | GLYCEROL, HTH-type transcriptional regulator rot | Authors: | Zhu, Y, Fan, X, Li, X, Teng, M. | Deposit date: | 2014-04-24 | Release date: | 2014-09-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of Rot, a global regulator of virulence genes in Staphylococcus aureus. Acta Crystallogr.,Sect.D, 70, 2014
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4LA1
| Crystal structure of SjTGR (thioredoxin glutathione reductase from Schistosoma japonicumi)complex with FAD | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | Authors: | Peng, Y, Wu, Q, Huang, F, Chen, J, Li, X, Zhou, X, Fan, X. | Deposit date: | 2013-06-18 | Release date: | 2014-07-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.348 Å) | Cite: | Crystal structure of SjTGR complex with FAD To be Published
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