6WUJ
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![BU of 6wuj by Molmil](/molmil-images/mine/6wuj) | Mitochondrial SAM complex - monomer in detergent | Descriptor: | Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein | Authors: | Ni, X, Botos, I, Diederichs, K. | Deposit date: | 2020-05-04 | Release date: | 2020-08-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis. Nat Commun, 11, 2020
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3RN5
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![BU of 3rn5 by Molmil](/molmil-images/mine/3rn5) | Structural basis of cytosolic DNA recognition by innate immune receptors | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*AP*AP*GP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*TP*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*G)-3'), ... | Authors: | Jin, T.C, Xiao, T. | Deposit date: | 2011-04-21 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
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3RNU
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![BU of 3rnu by Molmil](/molmil-images/mine/3rnu) | Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*GP*GP*CP*C)-3'), ... | Authors: | Jin, T.C, Xiao, T. | Deposit date: | 2011-04-22 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
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3RN2
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![BU of 3rn2 by Molmil](/molmil-images/mine/3rn2) | Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*TP*CP*TP*TP*TP*GP*AP*TP*GP*G)-3'), Interferon-inducible protein AIM2 | Authors: | Jin, T.C, Xiao, T. | Deposit date: | 2011-04-21 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
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3RLN
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![BU of 3rln by Molmil](/molmil-images/mine/3rln) | |
3RLO
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![BU of 3rlo by Molmil](/molmil-images/mine/3rlo) | Structural Basis of Cytosolic DNA Recognition by Innate Receptors | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, Gamma-interferon-inducible protein 16 | Authors: | Jin, T.C, Xiao, T. | Deposit date: | 2011-04-19 | Release date: | 2012-04-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
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5W0K
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![BU of 5w0k by Molmil](/molmil-images/mine/5w0k) | |
3UM3
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![BU of 3um3 by Molmil](/molmil-images/mine/3um3) | |
4FLH
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![BU of 4flh by Molmil](/molmil-images/mine/4flh) | Crystal structure of human PI3K-gamma in complex with AMG511 | Descriptor: | 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2012-06-14 | Release date: | 2012-08-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. J.Med.Chem., 55, 2012
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5WPZ
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![BU of 5wpz by Molmil](/molmil-images/mine/5wpz) | Crystal structure of MNDA PYD with MBP tag | Descriptor: | MBP-hMNDA-PYD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-22 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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6AF0
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![BU of 6af0 by Molmil](/molmil-images/mine/6af0) | Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila | Descriptor: | Cdc73 protein, Ctr9 protein, Paf1 protein | Authors: | Wang, Z, Deng, P, Zhou, Y. | Deposit date: | 2018-08-07 | Release date: | 2018-09-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XS5
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![BU of 5xs5 by Molmil](/molmil-images/mine/5xs5) | Structure of Coxsackievirus A6 (CVA6) virus procapsid particle | Descriptor: | Genome polyprotein | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Cheng, T, Li, S.W. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
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5WQ6
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![BU of 5wq6 by Molmil](/molmil-images/mine/5wq6) | Crystal Structure of hMNDA-PYD with MBP tag | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MBP tagged hMNDA-PYD, ... | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-23 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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3UM0
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![BU of 3um0 by Molmil](/molmil-images/mine/3um0) | |
3UM1
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![BU of 3um1 by Molmil](/molmil-images/mine/3um1) | |
3RAU
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![BU of 3rau by Molmil](/molmil-images/mine/3rau) | Crystal structure of the HD-PTP Bro1 domain | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | Authors: | Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T. | Deposit date: | 2011-03-28 | Release date: | 2011-09-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release. Structure, 19, 2011
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8SD3
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![BU of 8sd3 by Molmil](/molmil-images/mine/8sd3) | CryoEM structure of rat Kv2.1(1-598) wild type in nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-06 | Release date: | 2023-09-27 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Inactivation of the Kv2.1 channel through electromechanical coupling. Nature, 622, 2023
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8SDA
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![BU of 8sda by Molmil](/molmil-images/mine/8sda) | CryoEM structure of rat Kv2.1(1-598) L403A mutant in nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-06 | Release date: | 2023-09-27 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Inactivation of the Kv2.1 channel through electromechanical coupling. Nature, 622, 2023
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5XS7
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![BU of 5xs7 by Molmil](/molmil-images/mine/5xs7) | Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5 | Descriptor: | Genome polyprotein, Heavy chain of Fab 1D5, Light chain of Fab 1D5 | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
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3R9M
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![BU of 3r9m by Molmil](/molmil-images/mine/3r9m) | Crystal structure of the Brox Bro1 domain | Descriptor: | 1,2-ETHANEDIOL, BRO1 domain-containing protein BROX, FORMIC ACID | Authors: | Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T. | Deposit date: | 2011-03-25 | Release date: | 2011-09-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release. Structure, 19, 2011
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4QLC
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![BU of 4qlc by Molmil](/molmil-images/mine/4qlc) | Crystal structure of chromatosome at 3.5 angstrom resolution | Descriptor: | CITRIC ACID, DNA (167-mer), H5, ... | Authors: | Jiang, J.S, Zhou, B.R, Xiao, T.S, Bai, Y.W. | Deposit date: | 2014-06-11 | Release date: | 2015-07-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | Structural Mechanisms of Nucleosome Recognition by Linker Histones. Mol.Cell, 33 Suppl 1, 2015
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5XS4
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![BU of 5xs4 by Molmil](/molmil-images/mine/5xs4) | Structure of Coxsackievirus A6 (CVA6) virus A-particle | Descriptor: | Genome polyprotein | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
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4F1S
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![BU of 4f1s by Molmil](/molmil-images/mine/4f1s) | Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor | Descriptor: | N-(5-{[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-5-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]amino}-2-chloropyridin-3-yl)methanesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2012-05-07 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold. Bioorg.Med.Chem.Lett., 22, 2012
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3ULY
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![BU of 3uly by Molmil](/molmil-images/mine/3uly) | |
3UM2
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![BU of 3um2 by Molmil](/molmil-images/mine/3um2) | |