7K10

CryoEM structure of activated-form FATKIN domain of DNA-PK

Summary for 7K10

• Entry DOI: 10.2210/pdb7k10/pdb
• Related: 7K0Y
• EMDB information: 22618 22619
• Descriptor: DNA-dependent protein kinase catalytic subunit (1 entity in total)
• Functional Keywords: nhej, pikk kinase, v(d)j recombination, dna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 469673.22

Authors

Chen, X.,Gellert, M.,Yang, W. (deposition date: 2020-09-06, release date: 2021-01-06, Last modification date: 2024-03-06)

• Primary citation: Chen, X.,Xu, X.,Chen, Y.,Cheung, J.C.,Wang, H.,Jiang, J.,de Val, N.,Fox, T.,Gellert, M.,Yang, W.; Structure of an activated DNA-PK and its implications for NHEJ.; Mol.Cell, 81:801-810.e3, 2021; PubMed: 33385326; DOI: 10.1016/j.molcel.2020.12.015

Experimental method

ELECTRON MICROSCOPY (3.3 Å)