4TQ5
 
 | | Structure of a UbiA homolog from Archaeoglobus fulgidus | | Descriptor: | octyl beta-D-glucopyranoside, prenyltransferase | | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-06-10 | | Release date: | 2014-07-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2023 Å) | | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
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5WVE
 | | Apaf-1-Caspase-9 holoenzyme | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ... | | Authors: | Li, Y, Zhou, M, Hu, Q, Shi, Y. | | Deposit date: | 2016-12-24 | | Release date: | 2017-02-08 | | Last modified: | 2017-03-01 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6XKB
 | | Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD | | Descriptor: | S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION | | Authors: | Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-06-26 | | Release date: | 2021-01-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
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6PUA
 | | The 2.0 A Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | Authors: | Kim, Y, Maltseva, N, Stam, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-07-18 | | Release date: | 2019-09-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species.
Protein Sci., 29, 2020
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6M1S
 | | The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12o | | Descriptor: | 3-[5-[8-(ethylamino)-6-fluoranyl-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]oxy-2,2-dimethyl-propanoic acid, CHLORIDE ION, DNA gyrase subunit B, ... | | Authors: | Xu, Z.H, Zhou, Z. | | Deposit date: | 2020-02-26 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.254 Å) | | Cite: | Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.
J.Med.Chem., 63, 2020
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6M1J
 | | The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x | | Descriptor: | 1-[5-[6-fluoranyl-8-(methylamino)-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]cyclopropane-1-carboxylic acid, DIMETHYL SULFOXIDE, DNA gyrase subunit B, ... | | Authors: | Xu, Z.H, Zhou, Z. | | Deposit date: | 2020-02-26 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.701 Å) | | Cite: | Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.
J.Med.Chem., 63, 2020
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8XJV
 | | Structural basis for the linker histone H5-nucleosome binding and chromatin compaction | | Descriptor: | DNA, Histone H2A, Histone H2B 1.1, ... | | Authors: | Li, W.Y, Song, F, Zhu, P. | | Deposit date: | 2023-12-22 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction.
Cell Res., 34, 2024
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3DWH
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8AYV
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5HEC
 | | CgT structure in dimer | | Descriptor: | Putative glycosyltransferase (GalT1) | | Authors: | Zhang, H, Wu, H. | | Deposit date: | 2016-01-05 | | Release date: | 2016-08-31 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.395 Å) | | Cite: | New Helical Binding Domain Mediates a Glycosyltransferase Activity of a Bifunctional Protein.
J.Biol.Chem., 291, 2016
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2NDF
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2NDG
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2ND0
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2NCZ
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2ND1
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5TCZ
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3C8G
 | | Crystal structure of a possible transciptional regulator YggD from Shigella flexneri 2a str. 2457T | | Descriptor: | ACETATE ION, Putative transcriptional regulator | | Authors: | Tan, K, Borovilos, M, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-02-12 | | Release date: | 2008-02-19 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria.
J.Biol.Chem., 284, 2009
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5TZT
 | | Crystal structure of human CD47 ECD bound to Fab of C47B161 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy Chain of Fab C47B161, ... | | Authors: | Cardoso, R.M.F. | | Deposit date: | 2016-11-22 | | Release date: | 2017-03-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies.
Blood Cancer J, 7, 2017
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5TZ2
 | | Crystal structure of human CD47 ECD bound to Fab of C47B222 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C47B222 Fab Heavy Chain, ... | | Authors: | Cardoso, R.M.F. | | Deposit date: | 2016-11-21 | | Release date: | 2017-03-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies.
Blood Cancer J, 7, 2017
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5TZU
 | | Crystal structure of human CD47 ECD bound to Fab of B6H12.2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | Cardoso, R.M.F. | | Deposit date: | 2016-11-22 | | Release date: | 2017-03-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies.
Blood Cancer J, 7, 2017
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5VC8
 | | Crystal structure of the WHSC1 PWWP1 domain | | Descriptor: | DNA (5'-D(P*CP*TP*(DN))-3'), Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION, ... | | Authors: | Qin, S, Tempel, W, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-03-31 | | Release date: | 2017-06-28 | | Last modified: | 2021-08-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.
Biochem.Biophys.Res.Commun., 569, 2021
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3HR5
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7RVB
 | | High resolution map of molecular chaperone Artemin | | Descriptor: | Ferritin | | Authors: | Parvate, A.D, Powell, S.M, Brookreason, J.T, Novikova, I.V, Evans, J.E. | | Deposit date: | 2021-08-18 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (2.04 Å) | | Cite: | Cryo-EM structure of the diapause chaperone artemin.
Front Mol Biosci, 9, 2022
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6BPH
 | | Crystal structure of the chromodomain of RBBP1 | | Descriptor: | AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION | | Authors: | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-11-23 | | Release date: | 2017-12-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of chromo barrel domain of RBBP1.
Biochem. Biophys. Res. Commun., 496, 2018
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5GMZ
 | | Hepatitis B virus core protein Y132A mutant in complex with 4-methyl heteroaryldihydropyrimidine | | Descriptor: | (2S)-4,4-difluoro-1-[[(4S)-4-(4-fluorophenyl)-5-methoxycarbonyl-4-methyl-2-(1,3-thiazol-2-yl)-1H-pyrimidin-6-yl]methyl]pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ... | | Authors: | Xu, Z.H, Zhou, Z. | | Deposit date: | 2016-07-18 | | Release date: | 2016-08-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors
J.Med.Chem., 59, 2016
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