7X4K
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, Genome polyprotein, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3Y
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-01 | Release date: | 2023-06-07 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X35
| Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10) | Descriptor: | 8A10 heavy chain, 8A10 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7YHK
| Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | Descriptor: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | Deposit date: | 2022-07-13 | Release date: | 2022-08-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
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6L8T
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7XZO
| Formate-tetrahydrofolate ligase in complex with ATP | Descriptor: | (R,R)-2,3-BUTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Formate--tetrahydrofolate ligase, ... | Authors: | Fang, C.L, Zhang, Y. | Deposit date: | 2022-06-03 | Release date: | 2023-06-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Identification of FtfL as a novel target of berberine in intestinal bacteria. Bmc Biol., 21, 2023
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7XZN
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7XZP
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5XSJ
| XylFII-LytSN complex | Descriptor: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS, ... | Authors: | Li, J.X, Wang, C.Y, Zhang, P. | Deposit date: | 2017-06-14 | Release date: | 2017-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XSD
| XylFII-LytSN complex mutant - D103A | Descriptor: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS | Authors: | Li, J.X, Wang, C.Y, Zhang, P. | Deposit date: | 2017-06-13 | Release date: | 2017-08-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XSS
| XylFII molecule | Descriptor: | Periplasmic binding protein/LacI transcriptional regulator, beta-D-xylopyranose | Authors: | Li, J.X, Wang, C.Y, Zhang, P. | Deposit date: | 2017-06-15 | Release date: | 2017-08-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5Y9C
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5Y9E
| Crystal structure of HPV58 pentamer | Descriptor: | GLYCEROL, MAGNESIUM ION, Major capsid protein L1 | Authors: | Li, S.W, Li, Z.H. | Deposit date: | 2017-08-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.042 Å) | Cite: | Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus. MBio, 8, 2017
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5Y9F
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3EFL
| Crystal structure of the VEGFR2 kinase domain in complex with motesanib | Descriptor: | N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide, Vascular endothelial growth factor receptor 2 | Authors: | Kim, J.L, Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2008-09-09 | Release date: | 2009-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Motesanib To be Published
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7JKS
| Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ... | Authors: | Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. | Deposit date: | 2020-07-28 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
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7JKT
| Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in complex with HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core from strain d45-01dG5, ... | Authors: | Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. | Deposit date: | 2020-07-28 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
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6H86
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3U6J
| Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor | Descriptor: | N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide, Vascular endothelial growth factor receptor 2 | Authors: | Whittington, D.A, Long, A, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2011-10-12 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives. J.Med.Chem., 55, 2012
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7UBA
| Structure of fungal Hop1 CBR domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HORMA domain-containing protein, PENTAETHYLENE GLYCOL, ... | Authors: | Ur, S.N, Corbett, K.D. | Deposit date: | 2022-03-14 | Release date: | 2023-03-29 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation. Embo J., 43, 2024
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