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8CT9
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BU of 8ct9 by Molmil
CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-distal state
Descriptor: CARDIOLIPIN, Dynamin-like 120 kDa protein, mitochondrial
Authors:Du Pont, K.E, Aydin, H.
Deposit date:2022-05-13
Release date:2023-08-30
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural mechanism of mitochondrial membrane remodelling by human OPA1.
Nature, 620, 2023
5TX4
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BU of 5tx4 by Molmil
Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130
Descriptor: TGF-beta receptor type-2, Transforming growth factor beta-2
Authors:Hinck, A.P, Kim, S.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX2
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BU of 5tx2 by Molmil
Miniature TGF-beta2 3-mutant monomer
Descriptor: Transforming growth factor beta-2
Authors:Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX6
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BU of 5tx6 by Molmil
Structure of TGF-beta2 derivative with deletion of residues 52-71 and 10 single amino acid mutations (mmTGF-beta2-7M)
Descriptor: CALCIUM ION, Transforming growth factor beta-2
Authors:Petrunak, E.M, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5UR2
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BU of 5ur2 by Molmil
Crystal structure of proline utilization A (PutA) from Bdellovibrio bacteriovorus inactivated by N-propargylglycine
Descriptor: Bifunctional protein PutA, N-propargylglycine-modified flavin adenine dinucleotide
Authors:Tanner, J.J.
Deposit date:2017-02-09
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Biophysical investigation of type A PutAs reveals a conserved core oligomeric structure.
FEBS J., 284, 2017
2JVL
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BU of 2jvl by Molmil
NMR structure of the C-terminal domain of MBF1 of Trichoderma reesei
Descriptor: TrMBF1
Authors:Kopke Salinas, R, Tomaselli, S, Camilo, C.M, Valencia, E.Y, Farah, C.S, El-Dorry, H, Chambergo, F.S.
Deposit date:2007-09-20
Release date:2008-09-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal domain of multiprotein bridging factor 1 (MBF1) of Trichoderma reesei.
Proteins, 75, 2009
7NY7
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BU of 7ny7 by Molmil
Crystal structure of the Capsaspora owczarzaki macroH2A macrodomain in complex with ADP-ribose
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, Histone macroH2A1.1
Authors:Guberovic, I, Knobloch, G, Basquin, J, Buschbeck, M, Ladurner, A.G.
Deposit date:2021-03-21
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evolution of a histone variant involved in compartmental regulation of NAD metabolism.
Nat.Struct.Mol.Biol., 28, 2021
7NY6
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BU of 7ny6 by Molmil
Crystal structure of the Capsaspora owczarzaki macroH2A macrodomain
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Histone macroH2A1.1
Authors:Knobloch, G, Guberovic, I, Basquin, J, Buschbeck, M, Ladurner, A.G.
Deposit date:2021-03-21
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Evolution of a histone variant involved in compartmental regulation of NAD metabolism.
Nat.Struct.Mol.Biol., 28, 2021
4JDD
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BU of 4jdd by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-25
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
7O4O
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BU of 7o4o by Molmil
Structure of Staphylococcus aureus m1A22-tRNA methyltransferase in complex with S-adenosylhomocysteine
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Adenine(22)-N(1))-methyltransferase
Authors:Gloster, T.M, Czekster, C.M, da Silva, R.G.
Deposit date:2021-04-06
Release date:2022-04-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m 1 A22-tRNA methyltransferase TrmK.
J.Biol.Chem., 298, 2022
7O4N
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BU of 7o4n by Molmil
Structure of Staphylococcus aureus m1A22-tRNA methyltransferase in complex with S-adenosylmethionine
Descriptor: GLYCEROL, S-ADENOSYLMETHIONINE, tRNA (Adenine(22)-N(1))-methyltransferase
Authors:Gloster, T.M, Czekster, C.M, da Silva, R.G.
Deposit date:2021-04-06
Release date:2022-04-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m 1 A22-tRNA methyltransferase TrmK.
J.Biol.Chem., 298, 2022
7O4M
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BU of 7o4m by Molmil
Structure of Staphylococcus aureus m1A22-tRNA methyltransferase
Descriptor: CITRIC ACID, GLYCEROL, tRNA (Adenine(22)-N(1))-methyltransferase
Authors:Gloster, T.M, Czekster, C.M, da Silva, R.G.
Deposit date:2021-04-06
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m 1 A22-tRNA methyltransferase TrmK.
J.Biol.Chem., 298, 2022
7MK2
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BU of 7mk2 by Molmil
CryoEM Structure of NPR1
Descriptor: Regulatory protein NPR1, ZINC ION
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M, Bartesaghi, A, Zhou, P.
Deposit date:2021-04-21
Release date:2022-03-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
7MK3
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BU of 7mk3 by Molmil
Crystal structure of NPR1
Descriptor: CHLORIDE ION, GLYCEROL, Regulatory protein NPR1, ...
Authors:Cheng, J, Wu, Q, Zhou, P.
Deposit date:2021-04-21
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
4JC3
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BU of 4jc3 by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-21
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
1R03
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BU of 1r03 by Molmil
crystal structure of a human mitochondrial ferritin
Descriptor: MAGNESIUM ION, mitochondrial ferritin
Authors:Corsi, B, Santambrogio, P, Arosio, P, Levi, S, Langlois d'Estaintot, B, Granier, T, Gallois, B, Chevallier, J.M, Precigoux, G.
Deposit date:2003-09-19
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure and Biochemical Properties of the Human Mitochondrial Ferritin and its Mutant Ser144Ala
J.Mol.Biol., 340, 2004
5NQS
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BU of 5nqs by Molmil
Structure of the Arabidopsis Thaliana TOPLESS N-terminal domain
Descriptor: Protein TOPLESS
Authors:Nanao, M.H, Arevalillo, M.R, Vinos-Poyo, T, Parcy, F, Dumas, R.
Deposit date:2017-04-21
Release date:2017-07-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8SUK
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BU of 8suk by Molmil
Structure of Rhodococcus sp. USK13 DarR-c-di-AMP complex
Descriptor: DNA (5'-D(*AP*A)-3'), DarR, SULFATE ION
Authors:Schumacher, M.A.
Deposit date:2023-05-12
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8T5Y
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BU of 8t5y by Molmil
Structure of Rhodococcus sp. USK13 DarR(K44A)-cAMP complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DarR
Authors:Schumacher, M.A.
Deposit date:2023-06-14
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8SV6
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BU of 8sv6 by Molmil
Structure of the M. smegmatis DarR protein
Descriptor: Fatty acid metabolism regulator protein
Authors:Schumacher, M.A.
Deposit date:2023-05-15
Release date:2023-11-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8SVA
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BU of 8sva by Molmil
Structure of the Rhodococcus sp. USK13 DarR-20 bp DNA complex
Descriptor: DNA (5'-D(*TP*AP*GP*AP*TP*AP*CP*TP*CP*CP*GP*GP*AP*GP*TP*AP*TP*CP*TP*A)-3'), PHOSPHATE ION, TetR/AcrR family transcriptional regulator
Authors:Schumacher, M.A.
Deposit date:2023-05-15
Release date:2023-11-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8SUA
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BU of 8sua by Molmil
Structure of M. baixiangningiae DarR-ligand complex
Descriptor: 3-azanyl-3-(hydroxymethyl)-1,5,7,11-tetraoxa-6$l^{4}-boraspiro[5.5]undecan-9-ol, DarR
Authors:Schumacher, M.A.
Deposit date:2023-05-11
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8SVD
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BU of 8svd by Molmil
Structure of M. baixiangningiae DarR-DNA complex reveals novel dimer-of-dimers DNA binding
Descriptor: DNA (5'-D(P*TP*AP*GP*AP*TP*AP*CP*TP*CP*CP*GP*GP*AP*GP*TP*AP*TP*CP*TP*A)-3'), DarR
Authors:Schumacher, M.A.
Deposit date:2023-05-16
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
8U7B
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BU of 8u7b by Molmil
Crystal structure of Apo form of Short Prokaryotic Argonaute TIR-APAZ (SPARTA) heterodimer
Descriptor: MANGANESE (II) ION, PROLINE, Piwi domain-containing protein, ...
Authors:Kottur, J, Aggarwal, A.K.
Deposit date:2023-09-15
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Nucleic acid mediated activation of a short prokaryotic Argonaute immune system.
Nat Commun, 15, 2024
8TFK
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BU of 8tfk by Molmil
Cryo-EM structure of the Methanosarcina mazei glutamine synthetase (GS) with Met-Sox-P and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2023-07-11
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023

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数据于2024-07-31公开中

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